| Interacting proteins: P15336 and P27361 |
Pubmed |
SVM Score :0.0 |
| TNFalpha stimulation of endothelial cells induces transient phosphorylation of both ATF 2 and c JUN and induces marked activation of the c JUN N terminal kinase ( JNK 1 ) and p 38 but not extracellular signal regulated kinase ( ERK 1 ) . ^^^ |
|
| Interacting proteins: P15336 and P27361 |
Pubmed |
SVM Score :0.0 |
| The analysis of two distinct mitogen activated protein kinase pathways shows that stress activated protein kinase Jun N terminal kinase activation , resulting in the phosphorylation of ATF 2 , c Jun , and JunD , is required not only for the IL 1 but also for the TPA dependent induction , while the extracellular signal related kinase 1 ( ERK 1 ) and ERK 2 activation is involved in the TPA but not in the IL 1 dependent stimulation of the uPA enhancer . . ^^^ |
|
| Interacting proteins: P15336 and P27361 |
Pubmed |
SVM Score :0.0 |
| Decreased proliferation correlated with cell cycle independent inhibition of ERK 1 expression in ATF 2 clones . ^^^ Genetic and pharmacologic inhibition of ERK 1 activity was sufficient to reproduce the effects of ATF 2 on cell cycle progression and proliferation . ^^^ |
|
| Interacting proteins: P15336 and P27361 |
Pubmed |
SVM Score :0.0 |
| In vitro kinase assays revealed that ERK 1 , ERK 2 and MSK 1 , like p 38 kinase and JNK 2 , directly phosphorylate ATF 2 at Thr 71 , but addition of RSK 2 or Akt 1 had almost no effect . ^^^ |
|
| Interacting proteins: P15336 and P27361 |
Pubmed |
SVM Score :0.0 |
| CONCLUSION : The data from this study indicate that both p 38 and ERK 1 are spatially regulated in different uterine regions during pregnancy / labor and suggest that they may be involved in regulating the activity of ATF 2 isoforms and their subsequent effects on myometrial function . . ^^^ |
|
| Interacting proteins: P15336 and P27361 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P15336 and P27361 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P15336 and P27361 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P15336 and P27361 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P15336 and P27361 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P15336 and P27361 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P15336 and P27361 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P15336 and P27361 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P15336 and P27361 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P15336 and P27361 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P15336 and P27361 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P15336 and P27361 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P15336 and P27361 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P15336 and P27361 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P15336 and P27361 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P15336 and P27361 |
Pubmed |
SVM Score :0.0 |
| NA |
|