| We found that stomatin co immunoprecipitated and co localized with ASIC proteins in heterologous cells . ^^^ Moreover , stomatin altered the function of ASIC channels . ^^^ Stomatin potently reduced acid evoked currents generated by ASIC 3 without changing steady state protein levels or the amount of ASIC 3 expressed at the cell surface . ^^^ In contrast , stomatin accelerated the desensitization rate of ASIC 2 and heteromeric ASICs , whereas current amplitude was unaffected . ^^^ |