| Interacting proteins: P41225 and P26367 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P41225 and P26367 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P41225 and P26367 |
Pubmed |
SVM Score :0.88439872 |
| The proximal half of the LE 9 sequence contains three plausible sites of HMG domain recognition , and HMG domain containing transcription factors Sox 2 and Sox 3 activated LE 9 synergistically with Pax 6 . 0.88439872^^^ |
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| Interacting proteins: P41225 and P26367 |
Pubmed |
SVM Score :0.0 |
| Fate mapping shows that the transcriptional regulators Otx 2 , Pax 6 and Sox 3 are expressed in the presumptive lens ectoderm prior to lens differentiation . ^^^ Otx 2 appears first , followed by Pax 6 , during the stages of lens bias ( late neural plate stages ) ; expression of Sox 3 follows neural tube closure and lens specification . ^^^ Activation of Otx 2 , Pax 6 and Sox 3 in competent ectoderm occurs in response to the early inducing tissue , the anterior neural plate . ^^^ |
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| Interacting proteins: P41225 and P26367 |
Pubmed |
SVM Score :0.0 |
| Ectopic Sox 3 expression leads to ectopic expression of Pax 6 and Eya 1 in embryonic ectoderm and causes ectopic lens and otic vesicle formation . ^^^ |
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| Interacting proteins: P41225 and P26367 |
Pubmed |
SVM Score :0.0 |
| In animal cap assays , XmafB can induce Pax 6 , Xlens 1 and Sox 3 expression , but XL maf fails to induce Pax 6 and Xlens 1 expression . ^^^ |
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| Interacting proteins: P41225 and P26367 |
Pubmed |
SVM Score :0.0 |
| We analyzed the spatiotemporal pattern of expression of 15 transcription factors ( Six 1 , Six 4 , Eya 1 , Sox 3 , Sox 2 , Pax 6 , Pax 3 , Pax 2 , Pax 8 , Dlx 3 , Msx 1 , FoxI1c , Tbx 2 , Tbx 3 , Xiro 1 ) during placode development in Xenopus laevis from neural plate to late tail bud stages . ^^^ |
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| Interacting proteins: P41225 and P26367 |
Pubmed |
SVM Score :0.0 |
| Analysis of gene expression after knockdown of xMADML revealed significant alterations in the expression of some genes , including Pax 6 , xSix 3 , Sox 2 , and Sox 3 , suggesting that xMADML plays a role in regulating gene expression during development of the eye . ^^^ |
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