| Interacting proteins: Q969T4 and P25963 |
Pubmed |
SVM Score :0.0 |
| In the presence of an E 1 SUMO 1 activating enzyme , Ubch 9 conjugated SUMO 1 to IkappaBalpha primarily on K 21 , which is also utilized for ubiquitin modification . ^^^ |
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| Interacting proteins: Q969T4 and P25963 |
Pubmed |
SVM Score :0.0 |
| In the presence of SAE1 / SAE2 , Ubch 9 , and ATP , SUMO 1 was efficiently conjugated to the protein substrate IkappaBalpha . ^^^ As SAE1 / SAE2 , Ubch 9 , SUMO 1 , and IkappaBalpha are all homogeneous , recombinant proteins , it appears that SUMO 1 conjugation of IkappaBalpha in vitro does not require the equivalent of an E 3 ubiquitin protein ligase activity . . ^^^ |
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| Interacting proteins: Q969T4 and P25963 |
Pubmed |
SVM Score :0.0 |
| Reconstitution of the conjugation reaction with highly purified proteins demonstrated that in the presence of a novel E 1 SUMO 1 activating enzyme , Ubch 9 directly conjugated SUMO 1 to 1 kappa B alpha on residues K 21 and K 22 , which are also used for ubiquitin modification . ^^^ |
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