| Silencing ELKS expression by RNA interference blocked induced expression of NF kappaB target genes , including the NF kappaB inhibitor IkappaBalpha and proinflammatory genes such as cyclo oxygenase 2 and interleukin 8 . ^^^ ELKS likely functions by recruiting IkappaBalpha to the IKK complex and thus serves a regulatory function for IKK activation . . ^^^ |