| Interacting proteins: P23771 and P25791 |
Pubmed |
SVM Score :0.0 |
| Lmo 2 and GATA 3 associated expression in intraembryonic hemogenic sites . ^^^ To further understand the mechanisms involved in the generation of definitive hemopoietic stem cells , we analysed the expression of the hemopoietic related transcription factors Lmo 2 and GATA 3 during the early steps of mouse development ( 7 12 dpc ) , with a particular emphasis on intraembryonic hemogenic sites . ^^^ We show here that both Lmo 2 and GATA 3 are present in the intraembryonic regions known to give rise to hemopoietic precursors in vitro and in vivo , suggesting that they act together at key points of hemopoietic development . ( 1 ) Lmo 2 and GATA 3 are expressed in the caudal mesoderm during the phase of intraembryonic precursors determination . ( 2 ) A highly transient concomitant expression is observed in the caudal intraembryonic definitive endoderm , suggesting that these factors are involved in the specification of intraembryonic hemopoietic precursors . ( 3 ) Lmo 2 and GATA 3 are expressed within the hemopoietic clusters located in the aortic floor during fetal liver colonisation . ^^^ |
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| Interacting proteins: P23771 and P25791 |
Pubmed |
SVM Score :0.0 |
| Levels of Scl , Rbtn 2 , GATA 1 , and Ldb 1 expression were comparable in AML and APL blasts , while the levels of expression of Rbtn 1 , GATA 2 , and GATA 3 were absent or markedly lower in APL cells . ^^^ |
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| Interacting proteins: P23771 and P25791 |
Pubmed |
SVM Score :0.0 |
| We assigned the expression of GATA 2 , GATA 3 , and lmo 2 to AGM HSC , whereas erythromyeloid progenitors express only GATA 2 . ^^^ |
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| Interacting proteins: P23771 and P25791 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P23771 and P25791 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P23771 and P25791 |
Pubmed |
SVM Score :0.0 |
| NA |
|