| Interacting proteins: P25063 and P16109 |
Pubmed |
SVM Score :0.56534871 |
| Together our data show that CD 24 serves as a ligand for P selectin under physiological flow conditions . 0.56534871^^^ |
|
| Interacting proteins: P25063 and P16109 |
Pubmed |
SVM Score :0.54276196 |
| CD 24 has been identified as a ligand for P selectin in both mouse and human cells . 0.54276196^^^ |
|
| Interacting proteins: P25063 and P16109 |
Pubmed |
SVM Score :0.0 |
| Heat stable antigen ( CD 24 ) as ligand for mouse P selectin . ^^^ |
|
| Interacting proteins: P25063 and P16109 |
Pubmed |
SVM Score :0.0 |
| Heat stable antigen ( mouse CD 24 ) supports myeloid cell binding to endothelial and platelet P selectin . ^^^ Previously , we suggested that heat stable antigen ( HSA / mouse CD 24 ) , an extensively glycosylated cell surface molecule on many mouse cells , is a ligand for P selectin . ^^^ |
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| Interacting proteins: P25063 and P16109 |
Pubmed |
SVM Score :0.0 |
| Heat stable antigen ( mouse CD 24 ) in the brain : dual but distinct interaction with P selectin and L 1 . ^^^ |
|
| Interacting proteins: P25063 and P16109 |
Pubmed |
SVM Score :0.0 |
| CD 24 , a mucin type glycoprotein , is a ligand for P selectin on human tumor cells . ^^^ We report that CD 24 , a mucin type glycosylphosphatidylinositol linked cell surface molecule on human neutrophils , pre B lymphocytes , and many tumors can promote binding to P selectin . ^^^ Latex beads coated with purified CD 24 from the two carcinoma cell lines but also neutrophils could bind specifically to P selectin IgG . ^^^ The carcinoma cells and CD 24 beads derived from these cells could bind to activated platelets or P selectin transfected Chinese hamster ovary cells ( P CHO ) in a P selectin dependent manner and this binding was blocked by soluble CD 24 . ^^^ Transfection of human adenocarcinoma cells with CD 24 enhanced the P selectin dependent binding to activated platelets . ^^^ |
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| Interacting proteins: P25063 and P16109 |
Pubmed |
SVM Score :0.0 |
| We demonstrated before that CD 24 , a Mr 35 , 000 60 , 000 mucine type glycosylphosphatidylinositol linked cell surface molecule , can function as ligand for P selectin and that the sialylLex carbohydrate is essential for CD 24 mediated rolling of tumor cells on P selectin . ^^^ A 125 FucTVII single transfectants expressing sialylLex but not CD 24 did not show P selectin mediated lung arrest . ^^^ |
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| Interacting proteins: P25063 and P16109 |
Pubmed |
SVM Score :0.0 |
| We hypothesise that the decreased survival of NSCLC patients with strongly CD 24 positive tumours is related to an enhanced propensity of haematogenous metastasis formation , which might be P Selectin mediated . . ^^^ |
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| Interacting proteins: P25063 and P16109 |
Pubmed |
SVM Score :0.0 |
| The CD62P receptor and its soluble form sP selectin is a marker of platelet ( PLT ) activation , and constitutes a ligand for CD 24 antigen of neoplastic cells and tumor stroma components . ^^^ |
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| Interacting proteins: P25063 and P16109 |
Pubmed |
SVM Score :0.0 |
| Inhibition of human CD 24 binding to platelet bound P selectin by monoclonal antibody . ^^^ CD 24 , one of the mucin type ligands of P selectin , is expressed in various adenocarcinomas and may mediate the interaction between platelets and cancer cells . ^^^ To demonstrate the involvement and specificity of P selectin and / or CD 24 in the interaction , we adapted a fluorometric binding procedure to assay the binding of calcein AM labeled platelets to DU 145 cells grown on 96 well microplates in the presence or absence of antibodies against CD 24 or P selectin . ^^^ In conclusion , our results indicate that P selectin ligand CD 24 mediates the binding of platelets to prostate cancer line DU 145 cells in vitro . ^^^ |
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| Interacting proteins: P25063 and P16109 |
Pubmed |
SVM Score :0.0 |
| The glycosylphosphatidylinositol anchored membrane protein CD 24 functions as an adhesion molecule for P selectin and L 1 and plays a role in B cell development and neurogenesis . ^^^ Furthermore , in addition to promoting binding to P selectin , CD 24 expression also indirectly stimulated cell adhesion to fibronectin , collagens 1 and 4 , and laminin through the activation of alpha3beta1 and alpha4beta1 integrin activity . ^^^ |
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| Interacting proteins: P25063 and P16109 |
Pubmed |
SVM Score :0.0 |
| Except for its role as a ligand for P selectin on carcinoma and myeloid cells , a specific function for CD 24 has not been determined . ^^^ |
|
| Interacting proteins: P25063 and P16109 |
Pubmed |
SVM Score :0.0 |
| Functionally , CD 24 enhances the metastatic potential of malignant cells , because it has been identified as a ligand of P selectin , an adhesion receptor on activated endothelial cells and platelets . ^^^ |
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| Interacting proteins: P25063 and P16109 |
Pubmed |
SVM Score :0.0 |
| In monocytic ESb MP cells the molecule serves as a ligand for P selectin and triggering with CD 24 specific antibodies can activate VLA 5 / L1 mediated cell adhesion in these cells . ^^^ |
|
| Interacting proteins: P25063 and P16109 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P25063 and P16109 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P25063 and P16109 |
Pubmed |
SVM Score :0.0 |
| NA |
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