| Interacting proteins: P24863 and Q00526 |
Pubmed |
SVM Score :0.0 |
| Here we show that a non cdk 8 associated cellular pool of cyclin C combines with cdk 3 to stimulate pRb phosphorylation at S807 / 811 during the G0 / G1 transition , and that this phosphorylation is required for cells to exit G 0 efficiently . ^^^ |
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| Interacting proteins: P24863 and Q00526 |
Pubmed |
SVM Score :0.0 |
| Cyclin C binds the cyclin dependent kinases CDK 8 and CDK 3 , which regulate mRNA transcription and the cell cycle , respectively . ^^^ A conserved region explains promiscuous binding of cyclin C to CDK 8 and CDK 3 , and a non conserved region may be responsible for discrimination of CDK 8 against other CDKs involved in transcription . ^^^ |
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