Pubmed abstracts for Protein-Protein Interaction search result :


Interacting proteins: P23511 and P05412 Pubmed SVM Score :0.0
The effects of c Jun were abrogated by mutations in the ICE box and by co expression of dominant negative nuclear factor Y , subunit A ( NF YA ) . ^^^
Interacting proteins: P23511 and P05412 Pubmed SVM Score :0.0
Both AP 1 and Cbfa 1 like factors are required for the induction of interstitial collagenase by parathyroid hormone . ^^^ While DNA binding activity of AP 1 is increased upon PTH treatment , high basal level of Cbfa / Runt binding activity is detectable in untreated cells which is not further increased by PTH , suggesting that AP 1 and Cbfal contribute to transcriptional activation through different mechanisms . ^^^
Interacting proteins: P23511 and P05412 Pubmed SVM Score :0.0
Physical interaction of the activator protein 1 factors c Fos and c Jun with Cbfa 1 for collagenase 3 promoter activation . ^^^ Previously , we determined that the activator protein 1 ( AP 1 ) binding site and the runt domain ( RD ) binding site and their binding proteins , c Fos . c Jun and Cbfa , regulate the collagenase 3 promoter in parathyroid hormone treated and differentiating osteoblasts . ^^^ Here we show that Cbfa 1 and c Fos . c Jun appear to cooperatively bind the RD and AP 1 binding sites and form ternary structures in vitro . ^^^ In mammalian cells , overexpression of Cbfa 1 enhanced c Jun activation of AP 1 binding site promoter activity , demonstrating functional interaction . ^^^ Thus , we provide direct evidence that Cbfa 1 and c Fos . c Jun physically interact and cooperatively bind the AP 1 and RD binding sites in the collagenase 3 promoter . ^^^
Interacting proteins: P23511 and P05412 Pubmed SVM Score :0.0
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Interacting proteins: P23511 and P05412 Pubmed SVM Score :0.0
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Interacting proteins: P23511 and P05412 Pubmed SVM Score :0.0
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Interacting proteins: P23511 and P05412 Pubmed SVM Score :0.0
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Interacting proteins: P23511 and P05412 Pubmed SVM Score :0.0
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