| Interacting proteins: P43246 and P23508 |
Pubmed |
SVM Score :0.0 |
| No evidence for linkage was found with markers near MSH 2 , MLH 1 , MCC , APC , HMPS , CDKN2A , JP 1 , PTEN , KRAS 2 , TP 53 , or LKB 1 . ^^^ |
|
| Interacting proteins: P43246 and P23508 |
Pubmed |
SVM Score :0.0 |
| The MCC APC region could be formally excluded as the locus for HNPCC in seven families . ^^^ Based on haplotypes for MCC and APC the added pairwise logarithm of odds score for all nine families was 22 . 57 at the recombination fraction of 0 . 00 using more stringent criteria for the HNPCC phenotype and 22 . 67 for less stringent criteria . ^^^ |
|
| Interacting proteins: P43246 and P23508 |
Pubmed |
SVM Score :0.0 |
| To determine if the MCC , DCC or p 53 gene is associated with susceptibility to hereditary non polyposis colorectal cancer ( HNPCC ) , these genes in normal cells from 12 HNPCC patients were analysed by polymerase chain reaction single strand conformation polymorphism analysis . ^^^ Only one of nine HNPCC cancers showed mutations in the MCC and p 53 genes on the same analysis . ^^^ |
|
| Interacting proteins: P43246 and P23508 |
Pubmed |
SVM Score :0.0 |
| Linkage analysis shows that these susceptibility genes are different from the mouse homologs of the genes known to be somatically mutated in human colon cancer ( KRAS 2 , TP 53 , DCC , MCC , APC , MSH 2 , and probably also MLH 1 ) . ^^^ |
|
| Interacting proteins: P43246 and P23508 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P43246 and P23508 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P43246 and P23508 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P43246 and P23508 |
Pubmed |
SVM Score :0.0 |
| NA |
|