| Interacting proteins: P23469 and P62993 |
Pubmed |
SVM Score :0.61632572 |
| Through its SH 2 domain , Grb 2 can constitutively associate with transmembranal PTPepsilon in mammary tumors initiated by ras or neu , and can be induced to associate with cytoplasmic PTPepsilon in Jurkat T cells following stimulation of T cell receptor signaling by pervanadate . 0.61632572^^^ |
|
| Interacting proteins: P23469 and P62993 |
Pubmed |
SVM Score :0.0 |
| In contrast with full length tm PTPepsilon and cyt PTPepsilon , p 67 and p 65 are exclusively cytoplasmic , are not phosphorylated by Neu , and do not associate with Grb 2 in unstimulated cells . p 67 and p 65 are catalytically active and can reduce Src mediated phosphorylation of the Kv2 . 1 voltage gated potassium channel , albeit with reduced efficiency which most likely results from their cytoplasmic localization . ^^^ |
|