Interacting proteins: Q9H6Q3 and P22681 |
Pubmed |
SVM Score :0.92928292 |
In antigen receptor stimulated cells , SLAP 2 associated with several tyrosine phosphorylated proteins , including the ubiquitin ligase Cbl . 0.92928292^^^ |
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Interacting proteins: Q9H6Q3 and P22681 |
Pubmed |
SVM Score :0.80685314 |
SLAP 2 interacts with Cbl in vivo in a phosphorylation independent manner and with ZAP 70 and T cell receptor zeta chain upon T cell receptor activation . 0.80685314^^^ |
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Interacting proteins: Q9H6Q3 and P22681 |
Pubmed |
SVM Score :0.71017375 |
Following stimulation of primary thymocytes with anti CD 3 and anti CD 28 , SLAP 2 coimmunoprecipitates with tyrosine phosphorylated c Cbl and an unidentified protein of approximately 72 kDa . 0.71017375^^^ |
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Interacting proteins: Q9H6Q3 and P22681 |
Pubmed |
SVM Score :0.50503997 |
The SLAP 2 5 transcript encodes a putative protein of 210 amino acids that lacks the c Cbl interaction region , and consequently is impaired in its ability to both bind to c Cbl , and inhibit TCR signalling relative to SLAP 2 . . 0.50503997^^^ |
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Interacting proteins: Q9H6Q3 and P22681 |
Pubmed |
SVM Score :0.0 |
SLAP 2 also bound c Cbl , with the interaction being mediated , at least in part , by the unique C terminal domain of SLAP 2 . ^^^ |
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