Interacting proteins: Q08881 and P22681 |
Pubmed |
SVM Score :0.0 |
Initial studies with T cell lysates indicated that the Itk SH 3 domain bound Cbl , Fyn , and other tyrosine phosphoproteins from TCR stimulated Jurkat cells . ^^^ Under conditions of increased detergent stringency Sam 68 , Wiskott Aldrich Syndrome protein , and hnRNP K , but not Cbl and Fyn , were bound to the Itk SH 3 domain . ^^^ |
|
Interacting proteins: Q08881 and P22681 |
Pubmed |
SVM Score :0.0 |
Phosphorylation of LAT creates binding sites for the Src homology 2 ( SH 2 ) domains of other proteins , including PLC gamma 1 , Grb 2 , Gads , Grap , 3BP2 , and Shb , and indirectly binds SOS , c Cbl , Vav , SLP 76 , and Itk . ^^^ |
|
Interacting proteins: Q08881 and P22681 |
Pubmed |
SVM Score :0.0 |
Stimulation of surface CD 28 molecules on mast cells with anti CD 28 mAbs induced tyrosine phosphorylation of cellular proteins , including several protein tyrosine kinases and their substrates , such as Itk / Emt ( Emt ) , Btk , Syk , c Cbl , Shc , and Vav . ^^^ |
|
Interacting proteins: Q08881 and P22681 |
Pubmed |
SVM Score :0.0 |
NA |
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