Interacting proteins: P19235 and P22681 |
Pubmed |
SVM Score :0.0 |
The present study demonstrates that erythropoietin ( Epo ) and IL 3 induce tyrosine phosphorylation of the SH2 / SH3 containing adapter protein CrkL and its transient association with tyrosine phosphorylated SHP 2 , Shc , and Cbl in a murine IL 3 dependent cell line , 32D , expressing the Epo receptor ( EpoR ) . ^^^ |
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Interacting proteins: P19235 and P22681 |
Pubmed |
SVM Score :0.0 |
We demonstrate here that cross linking of alpha4beta1 by anti alpha 4 antibody induces tyrosine phosphorylation of Pyk 2 , Shc , and Cbl as well as binding of the adaptor protein CrkL with Cbl in a murine hematopoietic cell line , 32D / EpoR Wt . ^^^ In addition , adhesion of 32D / EpoR Wt cells to immobilized H 296 , a recombinant fibronectin peptide specific for alpha4beta1 , induced tyrosine phosphorylation of Jak 2 , the erythropoietin receptor ( EpoR ) , and the IL 3 receptor beta subunit as well as Pyk 2 , Shc , and Cbl . ^^^ |
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Interacting proteins: P19235 and P22681 |
Pubmed |
SVM Score :0.0 |
The adapter protein APS has previously been shown to be involved in recruiting the ubiquitin E 3 ligase c Cbl to the insulin receptor , the platelet derived growth factor beta receptor and the erythropoietin receptor , leading to increased degradation of the receptors and inhibition of mitogenesis . ^^^ |
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Interacting proteins: P19235 and P22681 |
Pubmed |
SVM Score :0.0 |
NA |
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Interacting proteins: P19235 and P22681 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: P19235 and P22681 |
Pubmed |
SVM Score :0.0 |
NA |
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