| Interacting proteins: P48380 and P22670 |
Pubmed |
SVM Score :0.0 |
| The transcription factor RFX 3 directs nodal cilium development and left right asymmetry specification . ^^^ |
|
| Interacting proteins: P48380 and P22670 |
Pubmed |
SVM Score :0.0 |
| We show here that RFX 1 belongs to a previously unidentified family of DNA binding proteins of which we have cloned three members , RFX 1 , RFX 2 , and RFX 3 , from humans and mice . ^^^ In other cell lines and tissues , RFX mRNA levels are variable , particularly for RFX 2 and RFX 3 . ^^^ |
|
| Interacting proteins: P48380 and P22670 |
Pubmed |
SVM Score :0.0 |
| Using an electrophoretic mobility shift assay , we further show that RFX 1 , RFX 2 , and RFX 3 homodimers and heterodimers specifically bind to the cis element of the IL 5Ralpha promoter . ^^^ The mRNA expression of RFX 1 , RFX 2 , and RFX 3 was detected ubiquitously , but in transient transfection assays , multimerized RFX binding sites in front of a basal promoter efficiently functioned in a tissue and lineage specific manner . ^^^ |
|
| Interacting proteins: P48380 and P22670 |
Pubmed |
SVM Score :0.0 |
| Here we show that site C binds members of the ubiquitously expressed RFX family of proteins , notably RFX 1 , RFX 3 , and the associated factor MIBP 1 , whereas sites B and D both bind the B cell specific activator protein BSAP / Pax5 . ^^^ |
|
| Interacting proteins: P48380 and P22670 |
Pubmed |
SVM Score :0.0 |
| RFX 4 contains evolutionarily conserved regions , including a RFX type DNA binding domain , a dimerization domain , and other conserved regions , and is closely related to RFX 1 , RFX 2 , and RFX 3 in structure . ^^^ Immunoprecipitation analyses showed that RFX 4 interacts physically with RFX 2 , RFX 3 , and RFX 4 itself but not with RFX 1 . ^^^ RFX 4 contains evolutionarily conserved regions , including a RFX type DNA binding domain , a dimerization domain , and other conserved regions , and is closely related to RFX 1 , RFX 2 , and RFX 3 in structure . ^^^ |
|
| Interacting proteins: P48380 and P22670 |
Pubmed |
SVM Score :0.0 |
| Unexpectedly , RFX 3 , which is abundantly expressed in neuronal cells , down regulated the transactivity as well , when it was expressed in non neuronal cells . ^^^ |
|
| Interacting proteins: P48380 and P22670 |
Pubmed |
SVM Score :0.0 |
| We report the identification of regulatory factor for 10 box 3 ( RFX 3 ) as a B10 . ^^^ We showed that in vitro translated RFX 3 , as well as RFX 1 and RFX 2 , was able to bind B10 . ^^^ |
|