| RFX 1 , a putative alpha Adducin interacting protein in a human kidney library . ^^^ Yeast two hybrid screen showed a specific interaction between human alpha Adducin and the regulatory factor for 10 box ( RFX 1 ) , a nuclear protein that down regulates the expression of several proteins in non neuronal cells . ^^^ The binding of alpha Adducin to RFX 1 and their nuclear co localization suggests that Adducin can have a role in modulating the transcriptional regulating activity of RFX I . . ^^^ |