| Interacting proteins: P04083 and P21980 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04083 and P21980 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04083 and P21980 |
Pubmed |
SVM Score :0.0 |
| Compared with those in poorly metastatic PLA801C subline , cytokeratin 18 , tissue transglutaminase , Rho GDP dissociation inhibitor 1 , tropomyosin , fibroblast type , IL 18 and annexin 1 were significantly up regulated , while protein disulfide isomerase , heat shock protein 60 , peroxiredoxin 1 , chlorine intracellular channel protein 1 ( CLI 1 ) and creatine kinase , B chain were significantly down regulated in the highly metastatic PLA801D subline . ^^^ |
|
| Interacting proteins: P04083 and P21980 |
Pubmed |
SVM Score :0.0 |
| Calcium induced intracellular cross linking of lipocortin 1 by tissue transglutaminase in A 431 cells . ^^^ This intracellular cross linking of lipocortin 1 is suggested to be mediated by the action of tissue transglutaminase , a Ca 2 ( + ) dependent protein cross linking enzyme . ^^^ In vitro incubation of purified lipocortin 1 with tissue transglutaminase resulted in the formation of covalently cross linked lipocortin 1 dimer , tetramer , and so on . ^^^ Collectively , these findings suggest that an increase of intracellular calcium concentration results in the attachment of lipocortin 1 onto the plasma membrane phospholipids through the C terminal domain of the molecule where the membrane bound lipocortin 1 is cross linked by the action of tissue transglutaminase through the N terminal domain . . ^^^ |
|
| Interacting proteins: P04083 and P21980 |
Pubmed |
SVM Score :0.0 |
| Cross linking of lipocortin 1 and enhancement of its Ca2+ sensitivity by tissue transglutaminase . ^^^ These immunoreactive proteins were identified to be covalently cross linked multimers of lipocortin 1 , since essentially the same cross linked multimers were observed when purified lipocortin 1 was incubated with tissue transglutaminase ( TGase ) in vitro . ^^^ |
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