Pubmed abstracts for Protein-Protein Interaction search result :


Interacting proteins: P12821 and P21964 Pubmed SVM Score :0.0
The activities of monoamine oxidase ( MAO ) , catechol O methyltransferase ( COMT ) , phenol sulfotransferase ( PST ) , alkaline phosphatase ( AP ) , gamma glutamyl transpeptidase ( GT ) , and angiotensin converting enzyme ( ACE ) were quantitated in primary cultures of bovine brain microvessel endothelial cell monolayers and cerebral gray matter . ^^^ Significant MAO A and B , cytosolic and membrane bound COMT , PST , AP , GT , and ACE activities are demonstrated in bovine gray matter . ^^^
Interacting proteins: P12821 and P21964 Pubmed SVM Score :0.0
Angiotensin converting enzyme ( ACE ) modulates dopamine turnover in the brain and catechol O methyltransferase ( COMT ) enzyme is an important agent in the metabolic inactivation of dopamine and norepinephrine . ^^^ Functional polymorphism in the COMT and ACE genes causes variation in enzyme activities . ^^^ We investigated the relationship of COMT and ACE gene polymorphism with response to conventional neuroleptic treatment in schizophrenia . ^^^ Genotyping of the COMT and ACE genes was performed by polymerase chain reaction . ^^^ The risk of having both low activity COMT and high activity ACE genotypes was over 10 times higher ( odds ratio=10 . 89 , 95 % CI 1 . 14 103 . 98 , P=0 . 04 ) in the non responders compared to responders . ^^^
Interacting proteins: P12821 and P21964 Pubmed SVM Score :0.0
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