Pubmed abstracts for Protein-Protein Interaction search result :

Interacting proteins: P21917 and P14867	Pubmed	SVM Score :0.0
The possible association of GABRA 1 with the psychopathology of major psychoses was tested both alone and in interaction with DRD 4 . ^^^ Four hundred and sixty one inpatients affected by major psychoses were assessed by the operational criteria checklist for psychotic illness ( OPCRIT ) and were also typed for the DRD 4 and GABRA 1 variants using PCR techniques . ^^^ GABRA 1 variants did not significantly influence the association of DRD 4 with delusional symptoms . ^^^
Interacting proteins: P21917 and P14867	Pubmed	SVM Score :0.0
The aim of this study is to investigate the influence of dopamine receptor D 2 ( DRD 2 ) , D 4 exon 3 ( DRD 4 ) , and gamma aminobutyric acid type A ( GABA ( A ) ) receptor alpha 1 subunit ( GABRA 1 ) gene variants on the efficacy of lithium prophylaxis in mood disorders . ^^^ Patients with mood disorders ( N = 125 : bipolar subtype , n = 100 ; major depressive disorder subtype , n = 25 ) were followed prospectively for an average of 53 months and were typed for DRD 2 ( Ser311 / Cys311 : n = 121 , VNTR : n = 63 ) , DRD 4 ( n = 125 ) and GABRA 1 ( n = 61 ) variants using polymerase chain reaction ( PCR ) techniques . ^^^ DRD 2 , DRD 4 and GABRA 1 variants were not associated with response to lithium . ^^^ DRD 2 , DRD 4 and GABRA 1 variants therefore do not appear to be associated with the outcome of lithium prophylaxis in mood disorders . . ^^^