| In this study human VDAC 1 was used as a bait protein in a two hybrid screening , which is based on the Sos recruitment system ( SRS ) . hVDAC 1 interacts with the dynein light chain Tctex 1 and the heat shock protein peptide binding protein 74 ( PBP 74 ) / mitochondrial heat shock protein 70 ( mtHSP 70 ) / glucose regulated protein 75 ( GRP 75 ) / mortalin in vivo . ^^^ |