| Interacting proteins: P20248 and P21675 |
Pubmed |
SVM Score :0.0 |
| TAFII 250 dependent transcription of cyclin A is directed by ATF activator proteins . ^^^ Here we report the mapping of an enhancer element in the cyclin A promoter ( TSRE ) that responds to mutations in TAFII 250 . ^^^ An analysis of chimeric promoter constructs reveals that the cyclin A TSRE can confer TAFII 250 dependence to the core promoter of c fos . ^^^ In addition , reciprocal hybrid promoter constructs suggest that TAFII 250 also contributes to the transcriptional properties of the cyclin A core promoter . ^^^ These defects in TAFII 250 apparently result in the down regulation of key molecules , such as cyclin A , which may be responsible for the ts 13 cell cycle arrest phenotype . . ^^^ |
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| Interacting proteins: P20248 and P21675 |
Pubmed |
SVM Score :0.0 |
| The MDM 2 C terminal region binds to TAFII 250 and is required for MDM 2 regulation of the cyclin A promoter . ^^^ There is a positive correlation between MDM 2 binding to TAFII 250 and MDM 2 activation of the cyclin A promoter . ^^^ The C terminal region of MDM 2 , which contains the Ring finger , interacts with TAFII 250 and is required for regulation of the cyclin A promoter by MDM 2 . ^^^ |
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| Interacting proteins: P20248 and P21675 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P20248 and P21675 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P20248 and P21675 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P20248 and P21675 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P20248 and P21675 |
Pubmed |
SVM Score :0.0 |
| NA |
|