Interacting proteins: P21583 and Q9Y240 |
Pubmed |
SVM Score :0.0 |
We have used a sensitive bioassay to investigate production of granulocyte colony stimulating factor ( G CSF ) , granulocyte macrophage colony stimulating factor ( GM CSF ) , interleukin ( IL ) 3 , IL 6 and stem cell growth factor ( SCF ) , by normal and AA stroma in long term bone marrow culture ( LTBMC ) . ^^^ |
|
Interacting proteins: P21583 and Q9Y240 |
Pubmed |
SVM Score :0.0 |
After ion exchange and size exclusion chromatography , one of the active molecules was shown to react with anti mouse stem cell growth factor ( SCF ) antibody and the molecular weight was determined as 40 45 kDa by sodium dodecylsulfate polyacrylamide gel electrophoresis ( SDS PAGE ) and Western blot . ^^^ |
|
Interacting proteins: P21583 and Q9Y240 |
Pubmed |
SVM Score :0.0 |
The recombinant protein was added to liquid cultures of CD34+ human marrow cells stimulated with IL 3 alone or with both IL 3 and either insulin like growth factor 2 ( IGF 2 ) or stem cell growth factor ( SCF ) . ^^^ |
|
Interacting proteins: P21583 and Q9Y240 |
Pubmed |
SVM Score :0.0 |
In contrast , rhSCGF alpha suppressed stem cell factor ( SCF ) stimulated erythroid bursts , indicating some competitive interaction between SCGF and SCF . rhSCGF alpha was synergistic with interleukin 3 and the flt 3 ligand to enhance GM colony growth , but not synergistic with those inducing ex vivo expansion of GM progenitor cells . ^^^ |
|
Interacting proteins: P21583 and Q9Y240 |
Pubmed |
SVM Score :0.0 |
Here , we show that the c kit ligand ( KL ) , a recently identified stem cell growth factor , at concentrations 10 100 times lower than that required to promote cell proliferation , enhances the release of histamine and leukotriene C 4 in response to IgE receptor crosslinking of human lung MC . ^^^ |
|
Interacting proteins: P21583 and Q9Y240 |
Pubmed |
SVM Score :0.0 |
In this report , we have examined the expression of these integrin chain genes by mature connective tissue mast cells ( CTMC ) and by bone marrow derived mast cells ( BMMC ) differentiated from bone marrow precursor cells in the presence of interleukin ( IL ) 3 and / or the c kit ligand ( also known as mast cell growth factor and stem cell growth factor ) . ^^^ |
|
Interacting proteins: P21583 and Q9Y240 |
Pubmed |
SVM Score :0.0 |
More recently , the Sl locus has been shown to encode a ligand for c kit , which is variously known as mast cell growth factor ( MGF ) , stem cell growth factor and c kit ligand . ^^^ |
|
Interacting proteins: P21583 and Q9Y240 |
Pubmed |
SVM Score :0.0 |
The current study investigates the potential role of the growth factor kit ligand ( KL ) / stem cell growth factor and its receptor c kit in normal OSE biology and ovarian cancer . ^^^ |
|
Interacting proteins: P21583 and Q9Y240 |
Pubmed |
SVM Score :0.0 |
At the same time , rh BMP 2 were implanted into the thigh muscle of normal Kun min mice for dynamic control observation of the implantation local morphological changes , colony forming units spleen ( CFU S ) and stem cell growth factor ( SCF ) expression of the stroma cells of ectopic ossicles induced by BMP . ^^^ |
|
Interacting proteins: P21583 and Q9Y240 |
Pubmed |
SVM Score :0.0 |
RESULTS : The optimal compositions of serum substitutes and the cytokine cocktail for HSC expansion in the MNC culture system were BIT ( 4 g / L BSA , 0 . 71 microg / mL insulin , and 27 . 81 microg / mL transferrin ) , and CC 9 ( 5 . 53 ng / mL TPO , 2 . 03 ng / mL IL 3 , 16 ng / mL SCF , 4 . 43 ng / mL FL , 2 . 36 ng / mL IL 6 , 1 . 91 ng / mL G CSF , 1 . 56 ng / mL GM CSF , 2 . 64 ng / mL SCGF , and 0 . 69 ng / mL IL 11 ) in the Iscove ' s modified Dulbecco ' s medium . ^^^ |
|
Interacting proteins: P21583 and Q9Y240 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: Q9Y240 and P21583 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: Q9Y240 and P21583 |
Pubmed |
SVM Score :0.0 |
Here , we show that the c kit ligand ( KL ) , a recently identified stem cell growth factor , at concentrations 10 100 times lower than that required to promote cell proliferation , enhances the release of histamine and leukotriene C 4 in response to IgE receptor crosslinking of human lung MC . ^^^ |
|
Interacting proteins: Q9Y240 and P21583 |
Pubmed |
SVM Score :0.0 |
In this report , we have examined the expression of these integrin chain genes by mature connective tissue mast cells ( CTMC ) and by bone marrow derived mast cells ( BMMC ) differentiated from bone marrow precursor cells in the presence of interleukin ( IL ) 3 and / or the c kit ligand ( also known as mast cell growth factor and stem cell growth factor ) . ^^^ |
|
Interacting proteins: Q9Y240 and P21583 |
Pubmed |
SVM Score :0.0 |
More recently , the Sl locus has been shown to encode a ligand for c kit , which is variously known as mast cell growth factor ( MGF ) , stem cell growth factor and c kit ligand . ^^^ |
|
Interacting proteins: Q9Y240 and P21583 |
Pubmed |
SVM Score :0.0 |
We have used a sensitive bioassay to investigate production of granulocyte colony stimulating factor ( G CSF ) , granulocyte macrophage colony stimulating factor ( GM CSF ) , interleukin ( IL ) 3 , IL 6 and stem cell growth factor ( SCF ) , by normal and AA stroma in long term bone marrow culture ( LTBMC ) . ^^^ |
|
Interacting proteins: Q9Y240 and P21583 |
Pubmed |
SVM Score :0.0 |
After ion exchange and size exclusion chromatography , one of the active molecules was shown to react with anti mouse stem cell growth factor ( SCF ) antibody and the molecular weight was determined as 40 45 kDa by sodium dodecylsulfate polyacrylamide gel electrophoresis ( SDS PAGE ) and Western blot . ^^^ |
|
Interacting proteins: Q9Y240 and P21583 |
Pubmed |
SVM Score :0.0 |
The recombinant protein was added to liquid cultures of CD34+ human marrow cells stimulated with IL 3 alone or with both IL 3 and either insulin like growth factor 2 ( IGF 2 ) or stem cell growth factor ( SCF ) . ^^^ |
|
Interacting proteins: Q9Y240 and P21583 |
Pubmed |
SVM Score :0.0 |
The current study investigates the potential role of the growth factor kit ligand ( KL ) / stem cell growth factor and its receptor c kit in normal OSE biology and ovarian cancer . ^^^ |
|
Interacting proteins: Q9Y240 and P21583 |
Pubmed |
SVM Score :0.0 |
At the same time , rh BMP 2 were implanted into the thigh muscle of normal Kun min mice for dynamic control observation of the implantation local morphological changes , colony forming units spleen ( CFU S ) and stem cell growth factor ( SCF ) expression of the stroma cells of ectopic ossicles induced by BMP . ^^^ |
|
Interacting proteins: Q9Y240 and P21583 |
Pubmed |
SVM Score :0.0 |
In contrast , rhSCGF alpha suppressed stem cell factor ( SCF ) stimulated erythroid bursts , indicating some competitive interaction between SCGF and SCF . rhSCGF alpha was synergistic with interleukin 3 and the flt 3 ligand to enhance GM colony growth , but not synergistic with those inducing ex vivo expansion of GM progenitor cells . ^^^ |
|
Interacting proteins: Q9Y240 and P21583 |
Pubmed |
SVM Score :0.0 |
RESULTS : The optimal compositions of serum substitutes and the cytokine cocktail for HSC expansion in the MNC culture system were BIT ( 4 g / L BSA , 0 . 71 microg / mL insulin , and 27 . 81 microg / mL transferrin ) , and CC 9 ( 5 . 53 ng / mL TPO , 2 . 03 ng / mL IL 3 , 16 ng / mL SCF , 4 . 43 ng / mL FL , 2 . 36 ng / mL IL 6 , 1 . 91 ng / mL G CSF , 1 . 56 ng / mL GM CSF , 2 . 64 ng / mL SCGF , and 0 . 69 ng / mL IL 11 ) in the Iscove ' s modified Dulbecco ' s medium . ^^^ |
|