| Interacting proteins: P49810 and P21333 |
Pubmed |
SVM Score :0.0 |
| Based on these results , we conclude that a single inoculation of Ad 5 vectored vaccines could be used as a tool to control FMD in outbreak situations . . ^^^ |
|
| Interacting proteins: P49810 and P21333 |
Pubmed |
SVM Score :0.0 |
| Swine inoculated with 10 ( 9 ) PFU of a control Ad 5 virus lacking the IFN gene and challenged 24 h later with FMDV developed typical signs of foot and mouth disease ( FMD ) , including fever , vesicular lesions , and viremia . ^^^ |
|
| Interacting proteins: P49810 and P21333 |
Pubmed |
SVM Score :0.0 |
| Human adenovirus type 5 ( Ad 5 ) has been evaluated as a novel gene delivery vector for the development of live viral vaccines for foot and mouth disease ( FMD ) . ^^^ In this study , we constructed an Ad 5 vector co expressing the capsid precursor proteins , P 1 , of FMD virus ( FMDV ) field strains A 24 Cruzeiro and O 1 Campos and examined the neutralizing antibody responses in swine after inoculation with the vector . ^^^ However , the overall neutralizing antibody response was considerably lower than that induced by a commercial FMD vaccine or a monovalent Ad 5 A24 vaccine . . ^^^ |
|
| Interacting proteins: P49810 and P21333 |
Pubmed |
SVM Score :0.0 |
| We have demonstrated previously that swine inoculated with replication defective human adenovirus type 5 ( Ad 5 ) vector expressing porcine IFN alpha ( Ad 5 PoIFN alpha ) were completely protected from FMD virus ( FMDV ) challenge . ^^^ |
|
| Interacting proteins: P49810 and P21333 |
Pubmed |
SVM Score :0.0 |
| A second problem with current FMD vaccines is that they do not induce protective immunity quickly , a drawback that is likely to be shared by our Ad 5 vectored empty capsid vaccine . ^^^ Administration of Ad 5 pIFNalpha protects swine from FMD as early as one day post administration . ^^^ |
|
| Interacting proteins: P49810 and P21333 |
Pubmed |
SVM Score :0.0 |
| Thus , pIFN alpha enhances the long term level of protection induced by the Ad 5 FMD vaccine , supporting its use as a potential adjuvant in FMD vaccination strategies . . ^^^ |
|
| Interacting proteins: P49810 and P21333 |
Pubmed |
SVM Score :0.0 |
| We report here that the loop regions of PS 1 and PS 2 interact with nonmuscle filamin ( actin binding protein 280 , ABP 280 ) and a structurally related protein ( filamin homolog 1 , Fh 1 ) . ^^^ |
|
| Interacting proteins: P49810 and P21333 |
Pubmed |
SVM Score :0.0 |
| Detailed temperature dependence of fluorescence spectra between 5 and 70 K are presented as well as 1 . 7 K fluorescence line narrowed ( FLN ) spectra of cores , confirming that PS 2 emission is composite . ^^^ |
|
| Interacting proteins: P49810 and P21333 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P49810 and P21333 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P49810 and P21333 |
Pubmed |
SVM Score :0.0 |
| NA |
|