| Actin binding protein 280 binds the stress activated protein kinase ( SAPK ) activator SEK 1 and is required for tumor necrosis factor alpha activation of SAPK in melanoma cells . 1.0094941^^^ SEK 1 , a dual specificity protein kinase that serves as one of the immediate upstream activators of the stress activated protein kinases ( SAPKs ) , associates specifically with the actin binding protein , ABP 280 , in vitro and in situ . 0.98394553^^^ |