| Interacting proteins: P18827 and P21246 |
Pubmed |
SVM Score :0.52286381 |
| Purified N syndecan binds in vitro with high affinity to several extracellular regulatory ligands , including basic fibroblast growth factor , the secreted adhesive protein heparin binding growth associated molecule , and a novel collagen like protein secreted by Schwann cells . 0.52286381^^^ |
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| Interacting proteins: P18827 and P21246 |
Pubmed |
SVM Score :0.0 |
| In many epithelio mesenchymal organs MK and HB GAM were codistributed with syndecan 1 , a cell surface proteoglycan . ^^^ In limb buds and facial processes , MK , HB GAM , and syndecan 1 were localized to the apical epithelium and the adjacent proliferating mesenchyme . ^^^ Both MK and HB GAM bound syndecan 1 in solid phase assays in a heparan sulfate dependent manner . ^^^ Neither MK nor HB GAM stimulated mesenchymal cell proliferation or induced syndecan 1 expression . ^^^ Taken together these results indicate that MK and HB GAM may play regulatory roles in differentiation and morphogenesis of the vertebrate embryo , particularly in epithelio mesenchymal organs , and suggest molecular interactions with syndecan 1 . . ^^^ |
|
| Interacting proteins: P18827 and P21246 |
Pubmed |
SVM Score :0.0 |
| The distribution patterns of FGFR 1 and PTN overlapped considerably with those of syndecan 1 and 3 mRNAs , respectively . ^^^ |
|
| Interacting proteins: P18827 and P21246 |
Pubmed |
SVM Score :0.0 |
| Stronger binding of MK and PTN to the CS chains of syndecan 4 than those of syndecan 1 was revealed , supporting the structural and functional differences . ^^^ The involvement of the core protein was also shown in the binding of MK and PTN to syndecan 1 , suggesting the possibility of cooperation with the HS and / or CS chains in the binding of these growth factors and their delivery to the cell surface receptors . . ^^^ |
|
| Interacting proteins: P18827 and P21246 |
Pubmed |
SVM Score :0.0 |
| NA |
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