| Interacting proteins: Q13017 and P20936 |
Pubmed |
SVM Score :0.0 |
| The N terminal portion of p 190 B contained several motifs characteristic of a GTPase domain , while its C terminus contained a Rho GAP domain . ^^^ |
|
| Interacting proteins: Q13017 and P20936 |
Pubmed |
SVM Score :0.0 |
| To date , two distinct genes coding for Ras GAP binding phosphoproteins of 190kDa , p 190 A and p 190 B , have been cloned from mammalian cells . ^^^ Like the p 190 B exon , the first exon of p 190 A is extremely large ( 3 . 7 kb in length ) , encoding both the GTPase and middle domains ( residues 1 1228 ) , but not the remaining GAP domain , suggesting a high conservation of genomic structure between two p 190 genes . ^^^ |
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| Interacting proteins: Q13017 and P20936 |
Pubmed |
SVM Score :0.0 |
| P 190 B Rho GTPase activating protein overexpression disrupts ductal morphogenesis and induces hyperplastic lesions in the developing mammary gland . p 190 B Rho GTPase activating protein is essential for mammary gland development because p 190 B deficiency prevents ductal morphogenesis . ^^^ These data demonstrate that precise control of p 190 B Rho GTPase activating protein activity is critical for normal branching morphogenesis during mammary gland development . . ^^^ |
|
| Interacting proteins: Q13017 and P20936 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q13017 and P20936 |
Pubmed |
SVM Score :0.0 |
| NA |
|