| Interacting proteins: P51636 and P20936 |
Pubmed |
SVM Score :0.0 |
| Six genes such as beta tubulin , high mobility group ( nonhistone chromosomal ) protein 1 , connective tissue growth factor , insulin like growth factor binding protein 2 , alpha tubulin , and RAS related gene were overexpressed in CAP therapy resistance group , whereas seven genes such as CD 9 antigen , alpha 2 macroglobulin , caveolin 2 , interleukin 1 receptor antagonist , Rho GTPase activating protein 1 , reticulon 3 , cyclin dependent kinase 10 , keratin 7 were underexpressed in CAP therapy resistance group . ^^^ |
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| Interacting proteins: P51636 and P20936 |
Pubmed |
SVM Score :0.0 |
| In support of this notion , we identify several SH 2 domain containing proteins , namely c Src , NCK , and Ras GAP , that interact with caveolin 2 in a phosphorylation dependent manner . ^^^ Furthermore , our co immunoprecipitation experiments show that caveolin 2 and Ras GAP are constitutively associated in c Src expressing NIH 3T3 cells , but not in untransfected NIH 3T3 cells . . ^^^ |
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| Interacting proteins: P51636 and P20936 |
Pubmed |
SVM Score :0.0 |
| PURPOSE : To demonstrate the interactions of PKCgamma with caveolin ( Cav ) 1 and connexin ( Cx ) 43 in lipid rafts and its regulation of gap junctions . ^^^ Overexpression of PKCgamma enhanced green fluorescent protein ( EGFP ) increased the interaction of PKCgamma EGFP with Cav 1 and Cx 43 and decreased gap junction Cx 43 plaques without exogenous growth factors . ^^^ Overexpression of a loss of function PKCgamma mutant did not decrease gap junction Cx 43 plaques or cause redistribution in lipid rafts , even though the PKCgamma mutant still interacted with Cav 1 and Cx 43 . ^^^ CONCLUSIONS : Activation of PKCgamma by TPA or IGF 1 stimulated the interaction of PKCgamma with Cav 1 and Cx 43 in lipid rafts , causing Cx 43 , Cav 1 , and PKCgamma to redistribute within the lipid rafts , and this resulted in a decrease in gap junction plaques . . ^^^ |
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| Interacting proteins: P51636 and P20936 |
Pubmed |
SVM Score :0.0 |
| Three SH 2 domain containing proteins , c Src , Nck , and Ras GAP , were found to associate with Cav 2 in a phosphorylation dependent manner . ^^^ |
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| Interacting proteins: P51636 and P20936 |
Pubmed |
SVM Score :0.0 |
| NA |
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| Interacting proteins: P51636 and P20936 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P51636 and P20936 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P51636 and P20936 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P51636 and P20936 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P51636 and P20936 |
Pubmed |
SVM Score :0.0 |
| NA |
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