Pubmed abstracts for Protein-Protein Interaction search result :

Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
In order to ascertain the significance of the regenerative process observed in vitro and its predictive value as to the capabilities of oligodendrocytes to ensheathe axons , we undertook an ultrastructural and immunocytochemical characterization of the multilamellar membranes to assess whether they contain all the myelin characteristic proteins , i . e . , myelin basic protein , proteolipid protein , 2 ' , 3 ' cyclic nucleotide 3 ' phosphodiesterase and myelin associated glycoprotein . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
Analysis of B cell responses in blood showed low numbers of cells secreting IgG , IgA , or IgM antibodies against MBP , PLP , myelin associated glycoprotein , and myelin oligodendrocyte glycoprotein both in MS affected and unaffected family members . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
Sixty tumors of the central and peripheral nervous system and seven brain metastases of extracranial carcinomas were examined using the peroxidase antiperoxidase method to study the expression of myelin basic protein ( MBP ) , myelin associated glycoprotein ( MAG ) and the HNK 1 / Leu 7 epitope . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
In the CNS , myelin basic protein ( MBP ) and myelin associated glycoprotein ( MAG ) mRNA levels were the same both in IL 2 treated and in control mice . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
Early myelination in zitter rat was investigated by light and electron microscopic observations , by immunostaining for myelin basic protein ( MBP ) , proteolipid protein ( PLP ) and myelin associated glycoprotein ( MAG ) , and by morphometric analysis from the 1st to the 28th day of age . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
T 3 increases the concentrations of mRNA transcribed from the following four myelin protein genes : myelin basic protein ( Mbp ) , myelin associated glycoprotein ( Mag ) , proteolipid protein ( Plp ) , and 2 ' , 3 ' cyclic nucleotide 3 ' phosphodiesterase ( Cnp ) . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
In the past decade , the primary amino acid sequences of the four proteins making up 90 % of the protein content of central nervous system myelin ( proteolipid protein , myelin basic protein , 2 ' , 3 ' cyclic nucleotide 3 ' phosphohydrolase , and myelin associated glycoprotein ) have been determined in several species . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
We have used this technique to detect and locate mRNA for myelin basic protein ( MBP ) , proteolipid protein ( PLP ) , 2 ' , 3 ' cyclic nucleotide 3 ' phosphodiesterase ( CNPase ) and myelin associated glycoprotein ( MAG ) in oligodendrocytes of 7 day old and adult rat brains . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
Immunocytochemistry for myelin basic protein ( MBP ) , myelin associated glycoprotein ( MAG ) , and 2 ' , 3 ' cyclic nucleotide 3 ' phosphodiesterase ( CNP ) revealed `` islands ' ' of myelin sheath like reaction product in both . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
Immunohistochemistry of peripheral nerve showed deficiency of the myelin proteins P 2 and P 0 , myelin basic protein , and myelin associated glycoprotein . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
Regions of demyelination and destruction of oligodendrocytes , showed reduced immunoreactivity of myelin basic protein ( MBP ) , myelin associated glycoprotein ( MAG ) , transferrin , and carbonic anhydrase C ( CA C ) . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
Such an observation has not been made with polyclonal antisera raised against purified myelin proteins like MBP and proteolipid protein , the major protein components of the myelin membrane , or myelin associated glycoprotein . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
We determined the temporal profile of expression of the genes encoding the P 0 glycoprotein , the myelin associated glycoprotein ( MAG ) , the myelin basic protein ( MBP ) , the proteolipid protein ( PLP ) , and 2 ' , 3 ' cyclic nucleotide 3 ' phosphodiesterase ( CNP ) in the sciatic nerve of rats . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
Cellular RNA was extracted from transected and age matched control optic nerves 5 , 10 , 20 , and 40 days after surgery , and levels of the following mRNAs were determined by slot blot procedures : PLP , MBP , myelin associated glycoprotein ( MAG ) , and 2 ' , 3 ' cyclic nucleotide 3 ' phosphodiesterase ( CNP ) . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
Although message levels for the myelin associated glycoprotein showed a similar temporal pattern , levels did not decrease as greatly and subsequently increased sooner than did levels for P 0 and myelin basic protein . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
The effect of optic nerve transection on myelin protein gene expression was studied in rats following axotomy at two ages : during active myelination ( 17 days of age ) and after peak expression of the genes ( 35 days of age ) . mRNA levels for proteolipid protein , myelin basic protein and myelin associated glycoprotein were assessed by northern and dot blotting and by in situ hybridization using tissue sections and cultured individual oligodendrocytes . ^^^ Transection at 17 days caused down regulation of mRNAs for proteolipid protein , myelin basic protein and myelin associated glycoprotein by 5 days after axotomy with an increase in GFAP mRNA . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
Myelin associated glycoprotein mRNA was upregulated prior to those for P 0 and myelin basic protein which had similar time courses . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
We evaluated the B cell response in cerebrospinal fluid ( CSF ) and blood by enumerating cells secreting antibodies to myelin associated glycoprotein ( MAG ) and , for reference , to myelin basic protein ( MBP ) , two myelin components which may constitute targets for autoimmune attack in multiple sclerosis ( MS ) . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
A nonradioactive in situ hybridization procedure was employed to study the distribution of mRNAs for myelin basic protein ( MBP ) , proteolipid protein ( PLP ) , myelin associated glycoprotein ( MAG ) and 2 ' , 3 ' cyclic nucleotide 3 ' phosphodiesterase ( CNP ) in oligodendrocytes in primary cultures of mouse brain . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
Umbilical cord blood of newborns and peripheral blood of healthy adults were investigated by an immunospot assay for cells secreting IgG , IgA and IgM antibodies against myelin basic protein ( MBP ) , proteolipid protein ( PLP ) , myelin associated glycoprotein ( MAG ) and myelin oligodendrocyte glycoprotein ( MOG ) which represent putative antigens for an autoimmune attack in multiple sclerosis ( MS ) and against acetylcholine receptor ( AChR ) which is considered an important autoantigen in myasthenia gravis . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
The abundance of the mRNAs for the major myelin proteins proteolipid protein , myelin basic protein , and myelin associated glycoprotein , expressed by oligodendrocytes , were also decreased in hypothyroid brains . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
The autoradiographic signals for 2 ' , 3 ' cyclic nucleotide 3 ' phosphodiesterase ( CNP ) , myelin basic protein ( MBP ) and myelin associated glycoprotein ( MAG ) mRNAs all decreased progressively in the postoperative time course and all the signals fell below the detectable level by the 7th postoperative day . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
Cell type specific antigens that were expressed by oligodendrocytes were galactocerebroside , myelin basic protein , proteolipid protein , 2 ' 3 ' cyclic nucleotide 3 ' phosphohydrolase and myelin associated glycoprotein . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
P 0 protein , P 2 protein , 170K Mr glycoprotein and ganglioside ( GGD ) of human peripheral nerve myelin and MBP , myelin associated glycoprotein ( MAG ) of human central nerve myelin were used as antigens . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
We have studied this problem ultrastructurally in organotypic tissue culture together with light microscopic immunocytochemistry for the astrocyte marker glial fibrillary acidic protein ( GFAP ) and for 2 oligodendrocyte markers , myelin basic protein ( MBP ) and myelin associated glycoprotein ( MAG ) . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
Eleven oligodendrogliomas were examined for the presence of myelin basic protein ( MBP ) and myelin associated glycoprotein ( MAG ) . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
The loss of myelin associated glycoprotein ( MAG ) and myelin basic protein ( MBP ) was compared by quantitative immunocytochemistry in demyelinating lesions of measles encephalomyelitis ( ME ) , multiple sclerosis ( MS ) , and progressive multifocal leukoencephalopathy ( PML ) . ^^^ A quantitation of myelin associated glycoprotein and myelin basic protein loss in different demyelinating diseases . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
Acute lesions were studied for differences in the distribution of myelin basic protein ( MBP ) and myelin associated glycoprotein ( MAG ) . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
Oligodendrocytes , the myelin forming cells of the central nervous system , were cultured from newborn rat brain and optic nerve to allow us to analyze whether two transmembranous myelin proteins , myelin associated glycoprotein ( MAG ) and proteolipid protein ( PLP ) , were expressed together with myelin basic protein ( MBP ) in defined medium with low serum and in the absence of neurons . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
Myelin associated glycoprotein ( MAG ) , 2 ' , 3 ' cyclic nucleotide 3 ' phosphodiesterase ( CNPase ) activity , myelin basic protein ( BP ) , and proteolipid protein ( PLP ) were quantitated in the brains of 20 day old Jimpy and control mice . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
Cell mediated immunity to myelin associated glycoprotein , proteolipid protein , and myelin basic protein in multiple sclerosis . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
Myelin basic protein ( BP ) , proteolipid protein ( PLP ) , myelin associated glycoprotein ( MAG ) , and 2 ' , 3 ' cyclic nucleotide 3 ' phosphodiesterase ( CNPase ) activity were quantitated in the brains and spinal cords of normal and myelin deficient ( md ) rats at 8 , 12 , 18 , and 25 days of age . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
The cellular and subcellular localization of the neural cell adhesion molecules L 1 , N CAM , and myelin associated glycoprotein ( MAG ) , their shared carbohydrate epitope L2 / HNK 1 , and the myelin basic protein ( MBP ) were studied by pre and post embedding immunoelectron microscopic labeling procedures in developing mouse sciatic nerve . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
Immunoprecipitates for myelin basic protein and / or myelin associated glycoprotein were found in oligodendrocytes , in their processes and associated to the myelin . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
The myelin associated glycoprotein ( MAG ) was quantitated in the CNS and PNS of quaking mice and the levels compared to the levels of myelin basic protein ( MBP ) and 2 ' : 3 ' cyclic nucleotide 3 ' phosphodiesterase ( CNPase ) activity . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
At birth , the clinically affected lambs had diffuse spinal cord hypomyelination , confirmed by immunocytochemical staining for myelin associated glycoprotein and myelin basic protein . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
Myelin associated glycoprotein ( Leu 7 ) , myelin basic protein ( MBP ) , S 100 protein , and , in most cases , glial fibrillary acidic protein ( GFAP ) and HLA DR / Ia ( LN 3 ) immunoreactivity were evaluated immunohistochemically using commercially available antibodies on 53 benign nerve sheath tumors and 12 sarcomas . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
Myelin associated glycoprotein ( MAG ) , myelin basic protein ( MBP ) , and proteolipid protein ( PLP ) were quantitated by immunoassays in nine plaque , inner periplaque , outer periplaque , and normal appearing white matter regions from brains of five multiple sclerosis patients and compared with the levels found in white matter samples of control subjects matched for age , postmortem time , and brain region . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
Oligodendrocytes were characterized by immunofluorescent staining with antibodies for the following markers : galactocerebroside , myelin basic protein , proteolipid protein , myelin associated glycoprotein and 2 ' , 3 ' cyclic nucleotide phosphohydrolase . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
Vibratome sections of brain were incubated with antisera to myelin basic protein ( MBP ) , myelin associated glycoprotein ( MAG ) , 2 ' : 3 ' cyclic nucleotide 3 ' phosphodiesterase ( CNP ) ( EC 3 . 1 . 4 . 37 ) , PLP , a synthetic PLP peptide , glial fibrillary acidic protein ( GFAP ) , and transferrin . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
The major myelin proteins were identified by antibodies on Western immunoblots , as were the 2 ' 3 ' cyclic nucleotide 3 ' phosphodiesterase ( CNP ) , actin , tubulin , myelin associated glycoprotein ( MGP ) and the 21 . 5 kDA MBP . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
In order to explore the virus host interactions , the histological features of the demyelinating disease were correlated with the spatial and temporal distribution of viral transcripts and the expression of oligodendrocyte specific genes ( myelin basic protein , proteolipid protein , myelin associated glycoprotein , and 2 ' , 3 ' cyclic nucleotide 3 ' phosphohydrolase ) in the spinal cord of diseased mice . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
Immunohistochemical examination using the myelin proteins , myelin basic protein and myelin associated glycoprotein , failed to show any difference in staining characteristics from normal , in contrast to the marked increase in glial fibrillary acidic protein accompanying the division of astrocytes . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
To study distributions of myelin associated glycoprotein ( MAG ) , myelin basic protein ( MBP ) , and glial fibrillary acidic protein ( GFAP ) in these lesions , paraffin and semithin epon sections of CNS from eight of these guinea pigs were immuno stained with antisera to these proteins according to the peroxidase antiperoxidase ( PAP ) method . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
Antibodies of the IgM , IgG and IgA class directed against one or more of the particulate fraction proteins tubulin , myelin basic protein , 69 K neurofilament protein , glial fibrillary acidic protein , myelin associated glycoprotein or Wolfgram protein were present in 94 , 54 and 47 % , respectively , of multiple sclerosis sera examined . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
Cells with oligodendrocyte like morphology that appear in large numbers throughout fresh lesions after acute myelin breakdown and before new myelin formation were found to express galactocerebroside , carbonic anhydrase , and 2 ' , 3 ' cyclic nucleotide 3 ' phosphohydrolase but not myelin associated glycoprotein or myelin basic protein . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
Staining patterns with myelin associated glycoprotein and myelin basic protein also suggest that normal myelination occurs in grafts transplanted to the brains of Quaking mice . . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
These markers were glial fibrillary acidic protein , myelin basic protein , myelin associated glycoprotein , neuron specific enolase , neurofilament protein , and fibronectin . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
The amount of myelin basic protein ( MBP ) in the brainstem of affected 4 week old pups was 2 . 6 % of that in age matched controls , while the levels of 2 ' 3 ' cyclic nucleotide phosphodiesterase ( CNP ) and myelin associated glycoprotein ( MAG ) were 10 % and 15 % of the control levels , respectively . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
Our results indicate that : overall incorporation expressed as cpm / mg of protein remains essentially constant and independent of the state of adhesion or time in culture ; B3 . f cells keep a low profile in the synthesis of the major myelin proteins but have a high uptake of precursors into 2 ' , 3 ' cyclic nucleotide phosphodiesterase , actin , and tubulin ; adhesion of oligodendrocytes to a polylysine substratum activates the synthesis and phosphorylation of myelin basic protein , and the synthesis and acylation of proteolipid protein and DM 20 ; over time in culture there is an increased synthesis and accumulation of these proteins and of myelin associated glycoprotein . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
Analysis revealed a lack of myelin specific lipids , but showed a residual immunoreactivity for myelin basic protein , myelin associated glycoprotein , and 2 ' , 3 ' cyclic nucleotide 3 ' phosphodiesterase . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
To study how viruses interact with oligodendroglia and produce demyelination , we immunostained paraffin and epon sections of lesions from patients with progressive multifocal leukoencephalopathy ( PML ) with antisera to papovaviruses , oligodendroglial myelin associated glycoprotein ( MAG ) , and myelin basic protein ( MBP ) according to the peroxidase antiperoxidase method . ^^^ Distribution of papovavirus , myelin associated glycoprotein , and myelin basic protein in progressive multifocal leukoencephalopathy lesions . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
The walls of the vacuoles were stained with the myelin basic protein but not with the myelin associated glycoprotein or the glial fibrillary acidic protein immunostains . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
To compare distributions of oligodendroglial myelin associated glycoprotein ( MAG ) and myelin basic protein ( BP ) during demyelination in acute experimental allergic encephalomyelitis ( EAE ) . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
A temporal series of demyelinating lesions in experimental canine distemper virus ( CDV ) infection was examined with immunohistological techniques demonstrating myelin basic protein ( MBP ) , myelin associated glycoprotein ( MAG ) , and glial fibrillary acidic protein ( GFAP ) on serial sections . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
Sections of the central nervous system of the leukodystrophic mouse mutants ' jimpy ' ( jp ) and ' myelin deficient ' ( mld ) , as well as of healthy littermates , were immunostained for glial fibrillary acidic protein ( GFA ) , myelin basic protein ( MBP ) and myelin associated glycoprotein ( MAG ) . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
One case of each of the following human leukodystrophies was examined immunocytochemically with antisera against myelin basic protein ( MBP ) , myelin associated glycoprotein ( MAG ) and gliofibrillary acidic protein ( GFA ) : Metachromatic leukodystrophy ( MLD ) , connatal adrenoleukodystrophy ( ALD ) , sudanophilic leukodystrophy of the adult ( SLD ) and connatal Pelizaeus Merzbacher disease ( PMD ) . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
Cerebrospinal fluid ( CSF ) from 40 multiple sclerosis ( MS ) patients was tested by solid phase radioimmunoassay ( RIA ) for ability to bind 2 common structural components of myelin and oligodendroglia , i . e . , to bind myelin basic protein ( MBP ) and myelin associated glycoprotein ( MAG ) . ^^^ CSF antibodies to myelin basic protein and to myelin associated glycoprotein in multiple sclerosis . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
Mixed glial cell cultures from neonatal dog cerebellum were harvested daily between 3 and 21 days after seeding and studied with immunocytochemical techniques for the demonstration of myelin associated glycoprotein ( MAG ) and myelin basic protein ( MBP ) . ^^^ Myelin associated glycoprotein is produced before myelin basic protein in cultured oligodendrocytes . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
Perineuronal satellite oligodendrocytes in the mouse have been investigated immunocytochemically using antisera to myelin basic protein and myelin associated glycoprotein . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
Myelin basic protein and myelin associated glycoprotein in chronic , relapsing experimental allergic encephalomyelitis . ^^^ One micron plastic sections of spinal cords from SJL / J mice with chronic relapsing experimental allergic encephalomyelitis ( EAE ) were reacted immunocytochemically with antiserum to myelin basic protein and myelin associated glycoprotein . ^^^ The distribution of myelin basic protein and myelin associated glycoprotein in myelin sheaths was compared in acute and chronic areas of demyelination . ^^^ Myelin associated glycoprotein was seen periaxonally in both normal myelin sheaths and sheaths which showed extensive splitting and ballooning as seen with toluidine blue stain and myelin basic protein antiserum . ^^^ At least at the level of the light microscope , myelin basic protein antiserum gave intense staining of myelin while antiserum to myelin associated glycoprotein showed little or no affinity to stain the myelin sheath itself , in contrast to other recent electron microscope observations . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
Active plaques from 4 patients with multiple sclerosis were examined for myelin associated glycoprotein ( MAG ) and myelin basic protein ( MBP ) using the peroxidase antiperoxidase ( PAP ) immunocytochemical procedure applied to paraffin sections . ^^^ The distribution of myelin associated glycoprotein and myelin basic protein in actively demyelinating multiple sclerosis lesions . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
Monoclonal antibodies against P 0 , myelin basic protein , or myelin associated glycoprotein were generated by fusing mouse myeloma cells with spleen cells from BALB / c mice immunized with central and peripheral nervous system myelin proteins . ^^^ Clone C6B5 ( iso type IgM ) secreted antibody ( ies ) that bound to both myelin basic protein and myelin associated glycoprotein , although binding of antibody to myelin basic protein as detected by the immunoblot technique appeared to be much less than to the myelin associated glycoprotein . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
The pattern of perivenular demyelination was also determined in 4 cases of measles encephalomyelitis using antibodies to myelin associated glycoprotein and myelin basic protein and a Luxol fast blue stain . ^^^ The pattern of loss of myelin associated glycoprotein and myelin basic protein in regions of perivenular demyelination resembles that reported in experimental allergic encephalomyelitis . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
The process of remyelination in the superior cerebellar peduncles of mice following demyelination with Cuprizone was studied immunohistochemically using antisera to myelin basic protein ( MBP ) and myelin associated glycoprotein ( MAG ) . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
In agreement with the close correlation between intrathecal IgG production and anti MBP ( myelin basic protein ) and anti MAG ( myelin associated glycoprotein ) antibody activity in the CSF of active MS cases , and parallel to the reduction of intrathecal IgG synthesis resulting from corticosteroids medication , we have found a significant reduction of anti MBP and anti MAG antibody activity expressed per 0 . 5 micrograms of CSF IgG in the same group of 40 MS patients subjected to high dose prednisone therapy . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
Myelin basic protein ( MBP ) and myelin associated glycoprotein ( MAG ) were localized immunocytochemically in 20 micrometers thick Vibratome and 1 micrometer thick Epon sections at 15 , 20 , 25 , and 30 days in vitro . ^^^ Myelin basic protein ( MBP ) and myelin associated glycoprotein ( MAG ) were localized immunocytochemically in 20 micrometers thick Vibratome and 1 micrometer thick Epon sections at 15 , 20 , 25 , and 30 days in vitro . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
Although T cell responses to the quantitatively major myelin proteins , myelin basic protein ( MBP ) and proteolipid protein ( PLP ) , are likely to be of importance in the course of multiple sclerosis ( MS ) , cell mediated autoimmune responses to other myelin antigens , in particular quantitatively minor myelin antigens , such as myelin associated glycoprotein ( MAG ) and the central nervous system specific myelin oligodendrocyte glycoprotein ( MOG ) , could also play a prevalent role in disease initiation or progression . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
Vibratome sections of cervical spinal cord from 15 human abortuses ranging in age from 15 to 24 gestational weeks ( GW ) were probed with immunohistochemical methods using antibodies to myelin basic protein ( MBP ) , 2 ' , 3 ' cyclic nucleotide 3 ' phosphodiesterase ( CNPase ) , and myelin associated glycoprotein ( MAG ) . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
Abnormal T cell responses to myelin components including myelin basic protein ( MBP ) , proteolipid protein ( PLP ) , and myelin associated glycoprotein ( MAG ) have been implicated in the pathogenesis of multiple sclerosis . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
The elution was monitored of the two major protein components , i . e . myelin basic protein ( MBP ) and proteolipid protein ( PLP ) , as well as of minor components , viz . myelin associated glycoprotein ( MAG ) and myelin / oligodendrocyte glycoprotein ( MOG ) . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
These proteins include myelin basic protein , myelin oligodendrocyte glycoprotein , and myelin associated glycoprotein . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
Similarly , incorporation of an amino acid precursor into the myelin associated glycoprotein ( MAG ) was increased by GM 3 treatment , but incorporation into myelin basic protein ( MBP ) was not affected . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
Peptide sequences from human myelin basic protein ( MBP ) , proteolipid protein ( PLP ) , myelin associated glycoprotein ( MAG ) , and myelin oligodendrocyte glycoprotein have been identified that bind to and form stable complexes with HLA A 2 . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
We focused on myelin basic protein ( MBP ) and myelin associated glycoprotein ( MAG ) gene expression . ^^^ Limited postnatal ethanol exposure permanently alters the expression of mRNAS encoding myelin basic protein and myelin associated glycoprotein in cerebellum . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
The expression of other myelin genes ( myelin basic protein , MBP ; myelin associated glycoprotein , MAG ; UDP galactose ceramide galactosyl transferase , CGT ) is unimpaired on the RNA level . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
The levels of mRNAs were 1 ) down regulated to basal levels ( P 0 and MBP mRNAs ) , 2 ) down regulated to undetectable levels ( myelin associated glycoprotein mRNAs ) , 3 ) upregulated ( mRNAs encoding 2 ' 3 ' cyclic nucleotide phosphodiesterase and beta actin ) , or 4 ) not stringently controlled by the removal of Schwann cell axonal contact ( proteolipid protein mRNAs ) . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
In addition to myelin basic protein ( MBP ) , other minor components of myelin , such as myelin associated glycoprotein ( MAG ) , may be important autoantigens in MS . ^^^ The T lymphocyte response against myelin associated glycoprotein and myelin basic protein in patients with multiple sclerosis . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
The antigen specific T cells were assessed by enumerating cells secreting interferon gamma ( IFN gamma ) in response to the myelin components P 0 , P 2 , myelin basic protein ( MBP ) and myelin associated glycoprotein ( MAG ) , and to 4 selected MBP peptides . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
Myelin basic protein ( MBP ) , proteolipid protein ( PLP ) , myelin associated glycoprotein ( MAG ) , and 2 ' , 3 ' cyclic nucleotide 3 ' phosphodiesterase ( CNP ) were measured by densitometric scanning of western blots . ^^^ Myelin basic protein ( MBP ) , proteolipid protein ( PLP ) , myelin associated glycoprotein ( MAG ) , and 2 ' , 3 ' cyclic nucleotide 3 ' phosphodiesterase ( CNP ) were measured by densitometric scanning of western blots . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
In serum free conditions , TGF beta blocked both Schwann cell myelination and the expression of the myelin related molecules galactocerebroside , P 0 , myelin associated glycoprotein , and myelin basic protein . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
In Krox 20 / mice , Schwann cells wrap their cytoplasmic processes only one and a half turns around the axon , and although they express the early myelin marker , myelin associated glycoprotein , late myelin gene products are absent , including those for protein zero and myelin basic protein . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
The final product , which migrated as two bands of molecular weight 28 kDa and 58 kDa , was highly pure as shown also by specific reactivity with monoclonal anti MOG antibodies on immunoblots in the absence of any detectable reactivity with antibodies specific for myelin basic protein , proteolipid protein and myelin associated glycoprotein . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
Numbers of IL 2 secreting cells were higher in MS patients compared to patients with AM + TH after stimulation with myelin proteolipid protein ( PLP ) , myelin associated glycoprotein ( MAG ) and myelin oligodendrocyte glycoprotein ( MOG ) , but not after stimulation with myelin basic protein ( MBP ) . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
To analyze Ag specific T cell autoimmunity in the newborn , umbilical cord blood cells of newborns were investigated by an immunospot assay for occurrence and numbers of cells secreting IFN gamma after short term culture in presence of myelin basic protein ( MBP ) , proteolipid protein , myelin associated glycoprotein , nicotinic acetylcholine receptor and the synthetic MBP amino acid sequences 1 20 , 63 88 , and 110 128 . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
Two putative human oligodendroglioma cell lines were examined for the expression of the oligodendrocyte associated genes , 2 ' , 3 ' cyclic nucleotide 3 ' phosphodiesterase , myelin basic protein , myelin proteolipid proteins , and myelin associated glycoprotein . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
The present study also shows that a restricted infection of oligodendrocytes with CDV down regulates the transcription of the major myelin genes coding for proteolipid protein , myelin basic protein ( MBP ) and myelin associated glycoprotein in a very similar way . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
Oligodendroglial trophic factor , therefore , generates a population of somewhat ' immature ' oligodendroglia , which are galactocerebroside , myelin associated glycoprotein and 2 ' , 3 ' cyclic nucleotide 3 ' phosphodiesterase positive but myelin basic protein and proteolipid protein negative . . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
Within 6 days in vitro they form extensive membranous sheets and acquire myelin associated glycoprotein ( MAG ) , proteolipid protein ( PLP ) , and myelin basic protein ( MBP ) . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
However , the temporospatial relationship of expression of two other major myelin proteins , proteolipid protein ( PLP ) and myelin associated glycoprotein ( MAG ) to that of MBP during fetal development has not been assessed in human tissues . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
In this review , the phosphorylation characteristics of myelin basic protein , protein zero ( P 0 ) , myelin associated glycoprotein and 2 ' 3 ' cyclic nucleotide 3 ' phosphodiesterase are summarized . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
In particular , the message for myelin basic protein ( and , in the case of treatment from days 3 to 6 , also that for myelin associated glycoprotein ) was decreased in cultures exposed to IFN gamma , and further depressed in cultures treated with IFN gamma and TNF alpha , while TNF alpha alone was ineffective . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
However , both PDGF treated and control oligodendrocytes exhibited myelin associated glycoprotein , proteolipid protein , and myelin basic protein immunoreactivity . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
Whole mounts of optic nerve , chiasm , and optic tract were sectioned horizontally and incubated with antibodies to myelin basic protein ( MBP ) , proteolipid protein ( PLP ) , myelin associated glycoprotein ( MAG ) , `` Rip , ' ' and the neurite inhibitory protein ( IN 1 ) , followed by visualization with diaminobenzidine and a peroxidase conjugated secondary antibody . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
As analyzed by indirect immunofluorescence , the A2B5 surface marker is absent , they express galactocerebroside and myelin specific proteins , such as myelin basic protein ( MBP ) , myelin associated glycoprotein ( MAG ) , proteolipidprotein ( PLP ) , and Wolfgram protein ( WP ) , but do not exhibit astrocytic properties , such as the expression of vimentin or the glial fibrillary acidic protein ( GFAP ) . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
Therefore , we examined the immunocytochemical staining pattern of antibodies directed against three proteins that are found along axons : myelin basic protein ( MBP ) , myelin associated glycoprotein ( MAG ) , and neuron glia cell adhesion molecule ( L 1 ) . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
Semiquantitative Western blotting was applied to measure serum IgM and IgG titers against specific myelin proteins , including P 2 , P 0 , myelin basic protein ( MBP ) , myelin associated glycoprotein ( MAG ) and PMP 22 . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
Using in situ hybridization of cultured rat OLG we found that mRNAs are localized to at least three different locations : 1 ) to the perinuclear region [ myelin associated glycoprotein ( MAG ) mRNA ] ; 2 ) mainly to the processes ( the mRNA for the 14 kDa isoform of MBP ) ; and 3 ) to both the perinuclear region and the primary processes [ 2 ' , 3 ' cyclic nucleotide phosphodiesterase ( CNPase ) and proteolipid protein ( PLP ) mRNAs ] . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
To assess the role of thyroid hormone on myelin gene expression , we have studied the effect of hypothyroidism on the mRNA steady state levels for the major myelin protein genes : myelin basic protein ( MBP ) , proteolipid protein ( PLP ) , myelin associated glycoprotein ( MAG ) and 2 ' : 3 ' cyclic nucleotide 3 ' phosphodiesterase ( CNP ) in different rat brain regions , during the first postnatal month . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
Autoimmune encephalomyelitis was induced by the adoptive transfer of CD4+ T line cells specific for either myelin basic protein , myelin oligodendrocyte glycoprotein ( MOG ) , myelin associated glycoprotein , S 100 beta , or glial fibrillary acidic protein . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
As expected , Western blot analysis indicates that in adult heterozygous TrJ animals , the level of PMP 22 is markedly decreased , similar to myelin basic protein and protein zero , whereas myelin associated glycoprotein is largely unaffected . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
By contrast , antibodies to periaxonal and structural components of myelin , such as MBP and myelin associated glycoprotein , are ineffective in inducing such MBP degradation . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
Plasma membrane processes of oligodendrocytes deficient in PLP and MBP , but not in myelin associated glycoprotein ( MAG ) , spirally wrap large diameter axons , tightly adhering at their extracytosolic surfaces and forming a pseudo compacted myelin . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
Immunohistochemical staining methods and antibodies against bovine proteolipid protein ( PLP ) , synthetic tridecapeptide of bovine PLP , human myelin basic protein ( MBP ) , human myelin associated glycoprotein ( MAG ) ; and 2 . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
Our previous analysis of the T cell reactivity to myelin antigens in a group of 24 patients with multiple sclerosis ( MS ) and 16 control individuals revealed that the autoimmune response to myelin oligodendrocyte glycoprotein ( MOG ) predominates in MS over that to myelin basic protein ( MBP ) , proteolipid protein or myelin associated glycoprotein , suggesting a prevalent role for the autoimmune response to MOG in the pathogenesis of MS . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
The developmental changes in expression of steady state mRNA that encode proteins that are important for myelination ( myelin basic protein , myelin associated glycoprotein , proteolipid protein , UDP galactose : ceramide galactosyltransferase ) and glial fibrillary acidic protein were investigated in the brain of the twitcher mouse , a model of human globoid cell leukodystrophy . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
Calcium activated neutral proteinase ( calpain ) is believed to participate in myelin protein degradation because known calpain substrates [ myelin basic protein ( MBP ) ; myelin associated glycoprotein ] are degraded in this disease . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
Molecular analysis revealed significant differences in the expression of neurofilament , neural cell adhesion molecule , myelin associated glycoprotein , and myelin basic protein . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
In addition , the expression of several major myelin proteins , including five isoforms of myelin basic protein , four isoforms of cyclic nucleotide 3 ' phosphodiesterase , and myelin associated glycoprotein , was markedly reduced in the brains of c myc transgenic mice as revealed by immunocytochemistry and by two dimensional immunoblots . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
Steady state levels of mRNA for myelin associated glycoprotein , myelin basic protein , and ceramide galactosyltransferase were already profoundly depressed after 1 week of Cuprizone exposure and were only 10 20 % of control values after 2 weeks . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
In all tracts , and at all developmental ages examined , apoptotic cells expressed the markers of mature oligodendrocytes , such as myelin basic protein , myelin associated glycoprotein , and the Rip antigen , but not chondroitin sulfate proteoglycan , a marker of oligodendrocyte precursors . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
In this study we determined the temporal expression pattern of PMP 22 in comparison to galactocerebroside ( GalC ) and myelin associated glycoprotein ( MAG ) , early constituents of PNS myelin , and to protein zero ( P 0 ) and myelin basic protein ( MBP ) , late components of myelin . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
We compared the expression of PMP 22 , P 0 , myelin basic protein ( MBP ) and myelin associated glycoprotein ( MAG ) in nerve biopsies from a 1 year old heterozygous Tr mouse ( Tr / + ) with that of a control mouse of the same age . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
Affected bitransgenic mice exhibited multiple hypomyelinated lesions in the white matter that did not stain with myelin specific antibodies against myelin basic protein , proteolipid protein , CNPase , and myelin associated glycoprotein . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
The MOBP 81 protein is found in myelin and in another subcellular fraction , whereas other myelin proteins , including MBP , 2 ' , 3 ' cyclic nucleotide 3 ' phosphodiesterase , and myelin associated glycoprotein , are largely restricted to myelin . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
We performed linkage analysis of MS to markers in chromosomal regions that include the genes encoding myelin basic protein ( MBP ) , proteolipid protein ( PLP ) , myelin associated glycoprotein ( MAG ) , oligodendrocyte myelin glycoprotein ( OMGP ) , and myelin oligodendrocyte glycoprotein ( MOG ) in a well characterized population of 65 multiplex MS families consisting of 399 total individuals , 169 affected with MS and 102 affected sibpairs . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
We have examined the lack of PMP 22 or Cx 32 on the distribution of other components of the myelin sheath including myelin basic protein ( MBP ) , E cadherin , and myelin associated glycoprotein ( MAG ) , as well as the delayed rectifying potassium channel Kv1 . 1 as an intrinsic membrane protein of axons . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
Dissociated oligodendrocytes , cultured for 18 hours to reflect their in vivo differentiation , express MBP and surface myelin associated glycoprotein at the same frequency as wild type . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
Others have indicated that myelin composition may also vary with respect to myelin basic protein ( MBP ) and proteolipid protein ( PLP ) , and the small ( S ) and large ( L ) isoforms of myelin associated glycoprotein ( MAG ) . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
Although all tested proteins could be floated to a low density fraction , proteolipid protein ( PLP ) , myelin basic protein ( MBP ) and myelin associated glycoprotein ( MAG ) were solubilized by the detergent extraction , and connexin 32 ( Cx 32 ) and oligodendrocyte specific protein ( OSP ) met only some of the criteria for DIGCEMs . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
The levels of connexin 32 ( Cx 32 ) and myelin associated glycoprotein ( MAG ) , two components of the incisures , are inversely proportional to the levels of MBP in sciatic nerves of mice affected by the shiverer ( shi ) mutation , while protein zero ( P 0 ) and peripheral membrane protein 22 ( PMP 22 ) , two structural components of compact myelin , remain constant . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
Double ( plp / mag / ) and triple ( plp / mbp / mag / ) null allelic mouse lines deficient in proteolipid protein ( PLP ) , myelin associated glycoprotein ( MAG ) , and myelin basic protein ( MBP ) were generated and characterized genetically , biochemically , and morphologically including their behavioral capacities . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
Immunohistochemical analysis of taiep brains and spinal cords revealed a gradual decrease in levels of several myelin proteins including myelin basic protein ( MBP ) , proteolipid protein ( PLP ) , myelin associated glycoprotein ( MAG ) , and 2 ' , 3 ' cyclic nucleotide 3 ' phosphodiesterase . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
Antibodies to myelin associated glycoprotein ( MAG ) , asialo GM 1 , beta 2 glycoprotein 1 , cardiolipin and myelin basic protein ( MBP ) were measured by ELISA . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
At 5 , 15 , 30 and 60 days after repair , 5 mm nerve segments distal to the repair were collected , and western blotting was used to measure myelin associated glycoprotein , myelin basic protein and low molecular weight neurofilament protein . ^^^ However , in the neurotrophin 4 group there was a significant increase ( to several times basal values ) in myelin associated glycoprotein and myelin basic protein at 5 15 days . ^^^ We conclude that neurotrophin 4 regulates the expression of myelin associated glycoprotein , myelin basic protein , and to a lesser extent low molecular weight neurofilament protein , during peripheral nerve regeneration . . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
Here we show that in rats that overexpress PLP , impairment of PLP transport from the cell body to the processes interferes with the translocation of other membrane proteins such as myelin associated glycoprotein ( MAG ) and myelin oligodendrocyte glycoprotein ( MOG ) , but not with peripherally translated MBP . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
Lipocalin type prostaglandin ( PG ) D synthase ( L PGDS ) , a protein expressed in mature OLs , was progressively upregulated in twitcher OLs ; whereas expression of OL associated proteins such as carbonic anhydrase 2 , myelin basic protein , and myelin associated glycoprotein was downregulated during demyelination in twitcher brains . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
Myelin associated glycoprotein levels were reduced in optic nerves of dt ( Tg 4 ) mice , and myelin basic protein levels were altered in optic nerves , sciatic nerves , and spinal cords of affected mice . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
In the presence of aTf , cells developed a multipolar morphology and showed an increased expression of O ( 4 ) , MBP , O ( 1 ) and myelin associated glycoprotein compared to controls . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
The antigens were myelin basic protein ( MBP ) , myelin associated glycoprotein ( MAG ) , ganglioside ( GM 1 ) , sulfatide ( SULF ) , chondroitin sulfate ( CONSO 4 ) , myelin oligodendrocyte glycoprotein ( MOG ) , alpha , beta crystallin ( alpha , beta CRYS ) , neurofilament proteins ( NAFP ) , tubulin and three cross reactive peptides , Chlamydia pneumoniae ( CPP ) , streptococcal M protein ( STM6P ) and milk butyrophilin ( BTN ) . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
The lack of PLP is accompanied by deficits in the other myelin proteins of the central nervous system , including myelin basic protein , myelin associated glycoprotein , and cyclic nucleotide phosphodiesterase . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
To further our understanding of the functions of the major myelin proteins , myelin basic protein ( MBP ) and proteolipid protein ( PLP ) , and other myelin proteins , such as 2 ' 3 ' cyclic nucleotide 3 ' phosphodiesterase ( CNP ) and myelin associated glycoprotein ( MAG ) , bovine brain myelin was extracted with Triton 10 100 , and protein complexes in the detergent soluble fraction were isolated by coimmunoprecipitation and sucrose density gradient sedimentation . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
Proteins situated on the periaxonal myelin membrane such as myelin associated glycoprotein disappeared early , within a few days after lesion , concomitantly with cytoskeletal axonal proteins , whereas compact myelin and outer myelin membrane proteins such as MBP and Nogo A remained for long intervals in the degenerating tracts . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
Double labeling experiments with antibodies against myelin basic protein showed no overlapping , while overlapping immunoreactivity was observed with antibodies against myelin associated glycoprotein . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
An immunohistochemical study , which can detect the specific expression of PLP , myelin basic protein , myelin associated glycoprotein , and platelet derived growth factor receptor alpha subunit in brain tissues , showed that the myelination was almost the same as that of age matched controls . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
RESULTS : In cytokine pretreated cultures , only 2 . 6 + / 1 . 1 % of total cells survived after a total of 9 days in vitro , whereas in untreated cultures most cells differentiated as shown by expression of myelin basic protein , myelin associated glycoprotein , 2 , 3 cyclic nucleotide 3 phosphodiesterase , and myelin oligodendrocyte specific protein . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
Serum samples were collected and analyzed with the enzyme linked immunosorbent assay ( ELISA ) technique for antibodies to myelin basic protein , myelin associated glycoprotein , ganglioside GM 1 , sulfatide , myelin oligodendrocyte glycoprotein , alpha B crystallin , chondroitin sulfate , tubulin , and neurofilament . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
Biochemical analysis revealed reduced myelin associated glycoprotein , myelin basic protein , and NF 155 protein levels in myelin and myelin derived rafts . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
Mouse mutants deficient in the myelin associated glycoprotein ( MAG ) and myelin basic protein ( MBP ) display subtle and severe myelin pathologies in the central nervous system ( CNS ) , respectively . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
These antibodies , which recognize myelin basic protein ( MBP ) , proteolipid protein ( PLP ) , myelin associated glycoprotein ( MAG ) , myelin oligodendrocyte glycoprotein ( MOG ) , oligodendrocyte specific protein ( OSP ) , 2 ' , 3 ' cyclic nucleotide 3 ' phosphodiesterase ( CNP ) , and transaldolase ( TAL ) , have been identified mostly in cerebrospinal fluid and in serum . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
Schwann cells change their gene and protein expression in response to mechanical stimuli as shear stress decreases the expression of myelin associated glycoprotein and myelin basic protein mRNA and protein for in vitro promyelinating Schwann cells . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
Shear stress alters the expression of myelin associated glycoprotein ( MAG ) and myelin basic protein ( MBP ) in Schwann cells . ^^^ Thus , we sought to determine how pure Schwann cells responded to a sustained shear stress in the form of laminar fluid flow by evaluating for proliferation , expression of S 100 , myelin associated glycoprotein ( MAG ) , and myelin basic protein ( MBP ) . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
METHODS : The expression of cyclic nucleotide phosphodiesterase , glial fibrillary acidic protein , myelin associated glycoprotein , myelin basic protein , and myelin proteolipid protein were assessed in the superior frontal gyrus and the primary motor cortex of control , uncomplicated alcoholic , and cirrhotic alcoholic cases . ^^^ RESULTS : Overall , the expression of cyclic nucleotide phosphodiesterase , glial fibrillary acidic protein , myelin associated glycoprotein , and myelin basic protein were significantly lower in the cirrhotic alcoholic cases compared with controls , with a similar tendency for myelin proteolipid protein . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
Immunohistochemical studies revealed significantly reduced levels of PLP / DM20 and other major myelin components such as myelin basic protein ( MBP ) , myelin associated glycoprotein ( MAG ) , and 2 ' , 3 ' cyclic nucleotide 3 ' phosphodiesterase ( CNP ) in shp myelin . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
These results were confirmed by : ( 1 ) myelin basic protein ( MBP ) immunohistochemistry ; ( 2 ) western blotting of myelin associated glycoprotein ( MAG ) and MBP ; ( 3 ) qRT PCR analyses of myelin associated oligodendrocytic basic protein ( MOBP ) , MAG , MBP and proteolipid protein ( PLP ) in hippocampus , cortex and spinal cord ; ( 4 ) quantitation of ethanolamine and choline plasmalogens , all core myelin components ; ( 5 ) evaluation of myelin content in brain sections employing toluidine blue staining ; and ( 6 ) ultrastructural evaluation of myelin sheath thickness via electron microscopy . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
Patients with both HMSN 1 and the other polyneuropathies had few cells in peripheral blood and in bone marrow producing antibodies binding to P 2 , MAG and MBP in a solid phase immunospot assay . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
The T cell repertoire in MS thus includes , besides myelin basic protein , proteolipid protein and myelin oligodendrocyte glycoprotein , also MAG and , in addition , measles and mumps virus . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
Relative to myelin purified from the same starting material , the 0 . 8M subfraction was enriched in MAG , CNPase , carbonic anhydrase and Na+ , K+ ATPase but was extremely low in PLP and MBP . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
Myelin gene expression ( P 0 , MBP , P 2 , and MAG ) was investigated during Wallerian degeneration and in the presence or absence of subsequent axonal regeneration and remyelination . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
A recent study on the relative disappearance of MAG versus MBP in primary and recurrent lesions of Theiler ' s infection had shown that numerous mononuclear cells in meninges and perivascular spaces specifically bound anti MAG antibody . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
Twenty eight oligodendrogliomas and seven oligoastrocytomas were immunotested by the peroxidase antiperoxidase ( PAP ) method with antiglial fibrillary acidic protein ( GFAP ) serum , anti Leu 7 monoclonal antibody ( Mab ) , anti myelin associated glycoprotein ( MAG ) Mab , anti myelin basic protein ( MBP ) serum , anti carbonic anhydrase C ( CA C ) serum and anti neuron specific enolase ( NSE ) serum . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
We analyzed the location and abundance of transcripts for the 4 CNS myelin protein genes , myelin basic protein ( MBP ) , proteolipid protein ( PLP ) , myelin associated glycoprotein ( MAG ) , and 2 ' , 3 ' cyclic nucleotide phosphohydrolase ( CNP ) , in the mouse cervical spinal cord from the time of rapid myelination until adulthood ( 8 45 d ) . ^^^ In contrast , MAG and the MBP exon 2 containing transcripts ( coding for the 21 . 5 and 17 kDa MBP isoforms ) decreased sharply between 8 and 20 d , suggesting that high levels of these transcripts are needed primarily during the initiation of myelination . ^^^ PLP , MAG , and CNP transcripts were clustered in the oligodendrocyte cell body , while MBP mRNAs were scattered throughout the cell body and processes . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
The expression of myelin protein genes in Schwann cells has been studied in situ hybridization . 35S UTP labelled , antisense and sense RNA probes to the major protein Po , myelin basic protein ( MBP ) , myelin associated glycoprotein ( MAG ) and proteolipid protein ( PLP ) were employed with paraffin embedded sections , teased fibres and dissociated Schwann cells from sciatic nerves of rats . ^^^ The expression of MAG and PLP mRNA was markedly lower than Po and MBP . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
Evaluation of antibody ( Ab ) responses at the cellular level , thereby bypassing draw backs inherent in determinations of circulating Ab levels , such as Ab binding to target , revealed that in one MS patient group , 57 % had , in CSF , cells secreting IgG Ab against myelin basic protein ( MBP ) and , in another MS group , 55 % had , in CSF , cells producing IgG Ab against myelin associated glycoprotein ( MAG ) ; both MBP and MAG are possible targets for immune attack in MS . ^^^ Anti MBP and anti MAG IgG antibody secreting cells could occur in parallel or independently . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
Double labelling studies demonstrated that MBP and MAG were produced by the same cells . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
We applied this technique to measure the relative variations of the MBP , Po , and MAG mRNA sequences in the normal trembler mouse model . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
PKC inhibition resulting from long term exposure to 4 beta phorbol 12 , 13 dibutyrate ( 4 beta PDB ) reduced steady state levels of MBP , PLP , MAG , CNP , and PKC alpha mRNAs , as detected by slot blots or in situ hybridization , and downregulated the oligodendrocyte specific markers O 4 , galactosyl cerebroside , and the major constituent proteins MBP and PLP , as detected by immunocytochemistry . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
MAG , myelin basic protein ( MBP ) , 2 ' , 3 ' cyclic nucleotide 3 ' phosphodiesterase ( CNP ) , proteolipid protein ( PLP ) and glial fibrillary acidic protein ( GFAP ) were quantified by western blot analysis in whole homogenates of spinal cords and hemispheres from affected goats at 1 , 3 and 6 days of age and from normal controls . ^^^ In mutant spinal cords , the deficits of MAG , CNP and PLP measured in whole homogenates corresponded reasonably well with the decreased myelin yields , but the levels of MBP were consistently much closer to control levels than those of the other myelin proteins . ^^^ In homogenates of mutant hemispheres , MAG , MBP , PLP and CNP were undetectable or at trace levels in comparison to controls . ( ABSTRACT TRUNCATED AT 250 WORDS ) . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
MS is characterized by elevated numbers of T cells recognizing MBP , PLP , MAG and MOG as well as the synthetic MBP amino acid sequences 1 20 , 63 88 , 89 101 , 96 118 , 110 128 and 148 165 , without immunodominance for any of these components . ^^^ PLP , MOG and MAG reactive T cells are strongly enriched in the patients ' CSF , as previously also shown for MBP reactive T cells . ^^^ Peripheral nerve trauma in form of diagnostic sural nerve biopsy is accompanied by transient elevation in blood of T cells recognizing MBP and MAG which are common to the central and peripheral nervous system , and to the peripheral nerve myelin proteins P 0 and P 2 . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
Because proteins can serve as excellent markers for the myelin formation process , we examined the developmental expression of several important myelin proteins ( PLP / DM 20 , MBP , CNP , MAG , and MOG ) in both pt mutant and control rabbit brain homogenates . ^^^ Expression of the investigated proteins occurs in rabbits as follows : CNP and MAG are already present at the early postnatal stage ; PLP / DM 20 and MBP appear about the 10th postnatal day ; MOG , expressed last , has been detected on the 28th postnatal day . ^^^ Whereas the MBP , CNP , MAG , and MOG content is only slightly reduced in mature pt mutant brain homogenates ( 80 90 % of control values ) , the amount of PLP corresponds to approximately 30 40 % of that present in controls . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
In our previous work , we presented developmental studies on the expression of several myelin specific proteins ( PLP / DM 20 , MBP , CNP , MAG , and MOG ) in the brain homogeates of both pt mutant and age matched control Chinchilla rabbits aged 1 120 postnatal days . ^^^ Whereas the content of CNP , MBP , and MAG in isolated myelin membrane fractions seemed close to normal , a drastic PLP deficiency was observed . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
We report here novel features of this disease , in particular a selective lack of detectable MAG in a large proportion of myelinated fibres containing P 0 , myelin basic protein ( MBP ) and periaxin . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
Of the known Schwann cell proteins , MBP , P 2 , MAG , PLP , PO , PMP 22 and Connexin 32 , gene defects of the latter three have recently been shown to be responsible for some forms of hereditary sensory and motor neuropathies . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
The levels of mRNA for MAG , MBP and PLP in affected goat spinal cords compared with those of controls were equally decreased to approximately 50 % for the three myelin proteins . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
These include MBP , PLP , MOG , MAG , CNP and S 100 . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
The cellular / regional expression of myelin specific proteins : PLP , MBP , CNP ase , MAG and MOG was investigated in the brains of 14 and 42 days old control and pt mutant rabbits . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
Western blot analyses of sciatic nerve homogenates showed that the levels of MBP , MAG , and P 0 were not significantly different in control and mutant animals . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
We show that MAG deficient Schwann cells do myelinate DRG neurons in vitro and express the myelin specific glycolipid galactocerebroside ( Gal C ) and the myelin proteins P 0 and MBP . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
Likewise , concentrations of myelin specific proteins ( MBP , myelin proteolipid protein , MAG , and 2 ' , 3 ' cyclic nucleotide , 3 ' phosphodiesterase ) were not significantly different in Igf 1 ( / ) and WT mice . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
Concomitantly , as investigated by RT PCR analysis , the transcriptional activity of c fos and c jun was stimulated , without altering mRNA expression of the myelin specific genes MBP , MAG , and PLP . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
Consistent with this hypothesis , Schwann cells in adult P 0 / mice display a novel molecular phenotype : PMP 22 expression is down regulated , MAG and PLP expression are up regulated , and MBP expression is unchanged . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
Neither myelin yields , nor levels of myelin basic protein and proteolipid protein , were decreased in comparison to control levels in 14 month old MAG null mice . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
We propose here that myelin basic protein ( MBP ) is prerequisite , which is more diffusely expressed than MAG in early stages of myelination . ^^^ MBP deficient mice show significant reduction of MAG positive immature oligodendroglia at early stages of myelination , although significant increase of such cells is noted in the adult . ^^^ The present study suggests that MBP is required for the regulation of MAG expression in oligodendroglia , involving Fyn therein . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
This was correlated with markedly reduced expression of the myelin proteins , proteolipid protein ( PLP ) , myelin basic protein ( MBP ) , 2 ' , 3 cyclic nucleotide 3 ' phosphodiesterase , and both large ( L ) and small ( S ) isoforms of myelin associated glycoprotein ( MAG ) . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
Myelination detected by immunostaining with anti myelin basic protein ( MBP ) antibody and anti myelin associated glycoprotein ( MAG ) antibody remained normal in the medial region of the corpus callosum . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
MBP , MOG , PLP , MAG ) , the presence of reactive T cells in blood and , further enriched , in the cerebrospinal fluid ( CSF ) , large numbers of B cells in the CSF secreting antibodies of multiple but unknown specificities , an increase of mononuclear cells ( MNC ) expressing and secreting both pro and anti inflammatory cytokines , including Th 1 cytokines interferon gamma ( IFN gamma ) and interleukin ( IL ) 6 , the Th 2 related IL 4 and IL 10 , and the Th 3 driven TGF beta , elevated numbers of MNC in both blood and CSF expressing a spectrum of metalloproteinases and their inhibitors , as well as many other aberrations . ^^^ Furthermore , a complete epitope spread affecting MBP , MOG , PLP , MAG and other myelin components is already present in ON . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
In this study , the steady state levels of mRNA and protein for five Schwann cell markers ( PMP 22 , P 0 , MBP , MAG , and LNGF R ) were assessed in primary Schwann cells and six representative Schwann cell lines ( RT 4 D6P2T , JS 1 , RSC 96 , R 3 , S 16 , and S16Y ) . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
We followed the expression and localization of L MAG in comparison to myelin basic protein ( MBP ) during myelination in dissociated embryonic rat brain cell cocultures . ^^^ Using immunofluorescence microscopy , we observed L MAG and MBP in oligodendrocyte ( OL ) cell bodies and processes before and at the onset of myelination . ^^^ At advanced stages of myelination , L MAG immunostaining decreased , and subsequently disappeared from OL soma and myelinated internodes , whereas MBP immunoreactivity decreased only in the OL soma . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
However , p 38 inhibition interfered with an early stage in myelination , thereby preventing ascorbate induced increases in the levels of mRNAs encoding MBP , MAG , and P ( 0 ) and reducing laminin deposition . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
The spinal cords of these Tg mice showed lower levels of the myelin proteins MAG and CNPase and of the 21 kDa isoform of MBP prior to the development of vacuoles . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
Myelin oligodendrocyte glycoprotein ( MOG ) , proteolipid protein ( PLP ) , MAPK , and some phosphotyrosine containing proteins were found to co cluster with GalC and MBP , but myelin associated glycoprotein ( MAG ) and phosphatidylinositol 4 , 5 bisphosphate ( PIP ( 2 ) ) did not . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
Genes identified in these lists included several genes that have been previously studied : MBP , Myelin PLP , NMDA receptor , MAG , astrocytic protein , Notch 3 , APP , Senescence , proteasome , Ferritin , signaling , cell cycle , iNOS , Chemokine , splicing , synapse , protein tags , and ribosomal proteins . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
In addition , cells were analysed by immunocytochemistry for A2B5 as well . as by RT PCR [ corrected ] and western blot analysis of the [ corrected ] myelin specific proteins [ corrected ] MBP , MAG and CNP . ^^^ Protein expression of MBP , MAG and CNP as well as mRNA expression , of MAG and MBP were considerably reduced after administration of INF and TNF . ^^^ Moreover , corticosteroids alleviated the cytokine induced inhibition in protein and mRNA expression [ corrected ] of MBP , MAG and CNP . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
At the molecular level , we find that Olig 1 regulates transcription of the major myelin specific genes , Mbp , Plp 1 , and Mag , and suppresses expression of a major astrocyte specific gene , Gfap . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
In addition , we examined how expression levels among the studied OMR genes are interrelated . mRNA of MAG , CNP , SOX 10 , CLDN 11 , and PMP 22 , but not MBP and MOBP , was reduced in the hippocampus and anterior cingulate cortex but not in the putamen of patients with schizophrenia . ^^^ Correlation and factor analyses revealed that mRNA levels for genes that did exhibit differential expression in schizophrenia ( MAG , CNP , SOX 10 , CLDN 11 , and PMP 2 ) , as opposed to those that did not ( MOBP and MBP ) , loaded on separate factors . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
In the brain of 14 day old transgenic mice , the DM 20 mRNA level was decreased , whereas the PLP , MBP , CNP , and MAG mRNA levels were increased . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
Here we show that human QKI mRNA levels can account for a high proportion ( 47 % ) of normal interindividual mRNA expression variation ( and covariation ) of six oligodendrocyte related genes ( PLP 1 , MAG , MBP , TF , SOX 10 , and CDKN1B ) in 55 human brain autopsy samples from individuals without psychiatric diagnoses . ^^^
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
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Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
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Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
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Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
NA
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
NA
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
NA
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
NA
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
NA
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
NA
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
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Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
NA
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
NA
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
NA
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
NA
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
NA
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
NA
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
NA
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
NA
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
NA
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
NA
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
NA
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
NA
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
NA
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
NA
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
NA
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
NA
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
NA
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
NA
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
NA
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
NA
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
NA
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
NA
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
NA
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
NA
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
NA
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
NA
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
NA
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
NA
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
NA
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
NA
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
NA
Interacting proteins: P20916 and P02686	Pubmed	SVM Score :0.0
NA