| Interacting proteins: O95999 and P20749 |
Pubmed |
SVM Score :0.0 |
| Our findings suggest that , although BCL 2 and BCL 6 are most often implicated in DLBCL , the possibility of the disruptions of BCL 3 , BCL 8 , BCL 9 , and BCL 10 as a `` primary event ' ' in DLBCL can not be ruled out . ^^^ Overall , M FISH has enhanced our ability to provide a comprehensive karyotypic analysis , and has helped in defining the importance of BCL 3 , BCL 8 , BCL 9 , and BCL 10 carrying breakpoints in DLBCL . . ^^^ |
|
| Interacting proteins: O95999 and P20749 |
Pubmed |
SVM Score :0.0 |
| The time courses of expression suggest that Bcl 2 and Bcl 10 ( L ) promote survival early in the response , whereas Bcl 3 acts later in the response . . ^^^ |
|
| Interacting proteins: O95999 and P20749 |
Pubmed |
SVM Score :0.0 |
| Bcl 10 is up regulated by NF kappaB and phosphorylated by Akt 1 and then complexes with Bcl 3 to enter the nucleus . ^^^ This study also demonstrates that Akt 1 , activated by TNFalpha , phosphorylates Bcl 10 at Ser 218 and Ser 231 and that phosphorylated Bcl 10 subsequently complexes with Bcl 3 to enter the nucleus . ^^^ Either inhibition of Akt 1 or depletion of Bcl 3 blocks Bcl 10 nuclear translocation . ^^^ |
|
| Interacting proteins: O95999 and P20749 |
Pubmed |
SVM Score :0.0 |
| NA |
|