| RNA polymerase 2 subunit 3 is retained in the cytoplasm by its interaction with HCR , the psoriasis vulgaris candidate gene product . ^^^ Furthermore , using human RPB 3 as bait in a yeast two hybrid system , we have isolated a novel RPB 3 cytoplasmic interacting protein , HCR . ^^^ In cycling myogenic C2C7 cells , we show that the RPB 3 protein directly interacts with HCR within the cytoplasm . ^^^ |