| Interacting proteins: Q99490 and P19174 |
Pubmed |
SVM Score :0.0 |
| Phospholipase C gamma 1 is a physiological guanine nucleotide exchange factor for the nuclear GTPase PIKE . ^^^ Here , we demonstrate that PLC gamma 1 acts as a guanine nucleotide exchange factor ( GEF ) for PIKE ( phosphatidylinositol 3 OH kinase ( PI ( 3 ) K ) enhancer ) . ^^^ |
|
| Interacting proteins: Q99490 and P19174 |
Pubmed |
SVM Score :0.0 |
| The nuclear PLC gamma 1 / PIKE S / PI 3 kinase signaling pathway seems to be an extension of the crosstalk between cytoplasmic PLC gamma 1 and PI 3 kinase . ^^^ |
|
| Interacting proteins: Q99490 and P19174 |
Pubmed |
SVM Score :0.0 |
| Nerve growth factor ( NGF ) treatment leads to PIKE activation by triggering the nuclear translocation of PLC gamma 1 , which acts as a physiological guanine nucleotide exchange factor ( GEF ) for PIKE . ^^^ |
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| Interacting proteins: Q99490 and P19174 |
Pubmed |
SVM Score :0.0 |
| PIKE predominantly distributes in the brain , and nerve growth factor stimulation triggers PIKE activation by provoking nuclear translocation of PLC gamma 1 , which acts as a physiologic guanine nucleotide exchange factor ( GEF ) for PIKE through its SH 3 domain . ^^^ |
|
| Interacting proteins: Q99490 and P19174 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q99490 and P19174 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q99490 and P19174 |
Pubmed |
SVM Score :0.0 |
| NA |
|