| Interacting proteins: Q13507 and P19174 |
Pubmed |
SVM Score :0.0 |
| Recently , we reported that phospholipase Cgamma 1 ( PLC gamma 1 ) binds to and regulates TRPC 3 channels , components of agonist induced Ca2+ entry into cells . ^^^ We have developed a gestalt algorithm to detect hitherto ' invisible ' PH and PH like domains , and now report that the partial PH domain of PLC gamma 1 interacts with a complementary partial PH like domain in TRPC 3 to elicit lipid binding and cell surface expression of TRPC 3 . ^^^ |
|
| Interacting proteins: Q13507 and P19174 |
Pubmed |
SVM Score :0.0 |
| In a recent issue of Nature , van Rossum et al . report binding of a `` split ' ' pleckstrin homology ( PH ) domain from phospholipase C gamma ( 1 ) to the TRPC 3 ion channel . ^^^ |
|
| Interacting proteins: Q13507 and P19174 |
Pubmed |
SVM Score :0.0 |
| Structural characterization of the split pleckstrin homology domain in phospholipase C gamma 1 and its interaction with TRPC 3 . ^^^ Multiple biochemical and biophysical experiments have argued against a direct interaction between TRPC 3 and the C terminal half of the PLC gamma 1 split PH domain . ^^^ |
|
| Interacting proteins: Q13507 and P19174 |
Pubmed |
SVM Score :0.0 |
| NA |
|