| Interacting proteins: P68104 and P19174 |
Pubmed |
SVM Score :1.0442177 |
| Direct interaction between EF 1alpha and PLC gamma 1 was confirmed by the in vitro binding experiment using purified PLC gamma 1 . 1.0442177^^^ In vivo interaction between EF 1alpha and PLC gamma 1 was confirmed by the immunoprecipitation experiment using anti EF 1alpha antibody . 0.98093013^^^ Furthermore , from the in vitro binding experiment , we could demonstrate that the carboxyl terminal region of EF 1alpha is involved in the interaction with PLC gamma 1 , and that both SH 2 and SH 3 domains of PLC gamma 1 are required for the interaction with EF 1alpha . 0.82275574^^^ The interaction between EF 1alpha and PLC gamma 1 was enhanced by EGF treatment . 0.68021259^^^ |
|
| Interacting proteins: P68104 and P19174 |
Pubmed |
SVM Score :0.60011828 |
| So the PH domain of PLC gamma 1 binds to both EF 1alpha and PIP ( 2 ) . 0.60011828^^^ |
|
| Interacting proteins: P68104 and P19174 |
Pubmed |
SVM Score :0.0 |
| However , even at concentrations of 0 . 1 to 1000 microM , no significant inhibitions were observed against other SH 2 domains binding such as the growth factor receptor binding protein 2 ( Grb 2 ) SH 2 domain to phosphopeptide of Shc and phospholipase Cgamma 1 ( PLCgamma 1 ) SH 2 domain to translational elongation factor 1alpha ( EF1alpha ) C terminal . ^^^ |
|