| Human ltk receptor tyrosine kinase binds to PLC gamma 1 , PI 3 K , GAP and Raf 1 in vivo . ^^^ Western blot analysis revealed that the wild type ltk protein was tyrosine phosphorylated in vivo and associated with SH 2 containing proteins , PLC gamma 1 , p 85 subunit of PI 3 K and GAP , in vivo . ^^^ |