| Interacting proteins: P19235 and P19174 |
Pubmed |
SVM Score :0.58699396 |
| PLCgamma 1 is rapidly tyrosine phosphorylated upon EPO stimulation and associates with EPO R in an SH 2 domain dependent manner . 0.58699396^^^ |
|
| Interacting proteins: P19235 and P19174 |
Pubmed |
SVM Score :0.0 |
| RESULTS : RT PCR analysis revealed that EpoR m RNA was expressed ; furthermore , it might be alternatively spliced in VSMC . rHuEPO induced tyrosine phosphorylation of PLC gamma 1 and activation of PKC . rHuEPO inhibited not only IL 1beta induced nitrite production , but also the expression of iNOS mRNA and protein . ^^^ CONCLUSION : rHuEPO inhibits IL 1beta induced NO production by suppressing iNOS mRNA and protein expressions through EpoR , and the PLC gamma 1 and PKC pathway may be involved . . ^^^ |
|
| Interacting proteins: P19235 and P19174 |
Pubmed |
SVM Score :0.0 |
| Deficiency of Btk results in reduced and delayed phosphorylation of the EpoR , Jak 2 , and downstream signaling molecules such as Stat 5 and PLCgamma 1 as well as in decreased responsiveness to Epo . ^^^ |
|
| Interacting proteins: P19235 and P19174 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P19235 and P19174 |
Pubmed |
SVM Score :0.0 |
| NA |
|