| Interacting proteins: P18847 and P19838 |
Pubmed |
SVM Score :0.70600944 |
| In addition , ATFa , ATF 2 , and ATF 3 interact directly with NF kappa B in vitro , linking two unrelated families of transcription factors in a novel protein protein interaction . 0.70600944^^^ |
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| Interacting proteins: P18847 and P19838 |
Pubmed |
SVM Score :0.0 |
| The immunohistochemical expression of cellular markers of neuronal damage ( activating transcription factor 3 ) or activation ( phosphorylated p 38 mitogen activated kinase , NF kappa B p 65 ) in dorsal root ganglia ( DRG ) tended to increase with both cytokine injections . ^^^ |
|
| Interacting proteins: P18847 and P19838 |
Pubmed |
SVM Score :0.0 |
| DNMT 1 knockdown also leads to an induction of a set of genes that are implicated in genotoxic stress response such as NF kappaB , JunB , ATF 3 , and GADD45beta ( growth arrest DNA damage 45beta gene ) . ^^^ |
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| Interacting proteins: P18847 and P19838 |
Pubmed |
SVM Score :0.0 |
| A splice variant of stress response gene ATF 3 counteracts NF kappaB dependent anti apoptosis through inhibiting recruitment of CREB binding protein / p300 coactivator . ^^^ Our study revealed that ATF3deltaZip2 counteracts anti apoptotic activity of NF kappaB , at least in part , by displacing positive cofactor CBP / p300 and provides insight into the mechanism by which ATF 3 regulates cell fate through alternative splicing in stress response . . ^^^ |
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| Interacting proteins: P18847 and P19838 |
Pubmed |
SVM Score :0.0 |
| Using null cells for ATF 3 and for the p 65 subunit of NF kappaB , we showed that induction of apoptosis by PKR at late times of infection was dependent on ATF 3 expression and regulated by NF kappaB activation . ^^^ |
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| Interacting proteins: P18847 and P19838 |
Pubmed |
SVM Score :0.0 |
| Promoter analysis of the putative ATF 3 regulated gene cluster demonstrated an over representation of closely apposed ATF 3 and NF kappaB binding sites , which was verified by chromatin immunoprecipitation and hybridization to a DNA microarray . ^^^ ATF 3 and Rel ( a component of NF kappaB ) were shown to bind to the regulatory regions of these genes upon macrophage activation . ^^^ A kinetic model of Il 6 and Il12b messenger RNA expression as a function of ATF 3 and NF kappaB promoter binding predicted that ATF 3 is a negative regulator of Il 6 and Il12b transcription , and this hypothesis was validated using Atf 3 null mice . ^^^ |
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| Interacting proteins: P18847 and P19838 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P18847 and P19838 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P18847 and P19838 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P18847 and P19838 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P18847 and P19838 |
Pubmed |
SVM Score :0.0 |
| NA |
|