| Interacting proteins: P18847 and P15336 |
Pubmed |
SVM Score :0.0 |
| ATF 2 and ATF 3 were considerably smaller ( molecular weights approximately 1 , 355 and 1 , 060 , respectively ) . ^^^ |
|
| Interacting proteins: P18847 and P15336 |
Pubmed |
SVM Score :0.0 |
| In addition , ATFa , ATF 2 , and ATF 3 interact directly with NF kappa B in vitro , linking two unrelated families of transcription factors in a novel protein protein interaction . ^^^ |
|
| Interacting proteins: P18847 and P15336 |
Pubmed |
SVM Score :0.0 |
| After 40 min of renal ischemia followed by reperfusion for as little as 5 min , binding of ATF 2 and c Jun , but not ATF 3 or CREB ( cAMP response element binding protein ) , to oligonucleotides containing either an ATF / cAMP response element ( ATF / CRE ) or the jun2TRE from the c jun promoter , was significantly increased . ^^^ |
|
| Interacting proteins: P18847 and P15336 |
Pubmed |
SVM Score :0.0 |
| Significantly , co transfection of DNAs expressing ATF 2 and c Jun activates the ATF 3 promoter . ^^^ |
|
| Interacting proteins: P18847 and P15336 |
Pubmed |
SVM Score :0.0 |
| However , transient co expression of ATF 3 but not ATF 2 selectively attenuates the FGF 2 component of induction . ^^^ |
|
| Interacting proteins: P18847 and P15336 |
Pubmed |
SVM Score :0.0 |
| The protein complexes interacting with CREL were not recognized by antibodies specific for CRE binding proteins CREB 1 and CREB 2 , or activating transcription factors ATF 1 , ATF 2 and ATF 3 . ^^^ |
|
| Interacting proteins: P18847 and P15336 |
Pubmed |
SVM Score :0.0 |
| METHODS : The adult rat optic nerve was crushed intraorbitally , and expression profiles of ATF 3 , ATF 2 , and phosphorylated c Jun ( p c Jun ) were examined by immunohistochemistry and ISH . ^^^ A higher degree of colocalization was observed for ATF 3 and c Jun than the modest codetection for ATF 2 and c Jun . ^^^ |
|
| Interacting proteins: P18847 and P15336 |
Pubmed |
SVM Score :0.0 |
| Gel shift , immunoprecipitation , and cotransfection assays demonstrated that a complex ( or complexes ) containing ATF 2 , c Jun , and ATF 3 increased binding to the ATF / CRE site in the homocysteine treated cells and activated the ATF 3 gene expression , while ATF 3 appeared to repress its own promoter . ^^^ |
|
| Interacting proteins: P18847 and P15336 |
Pubmed |
SVM Score :0.0 |
| The total level of CREB 1 , ATF 2 , and ATF 3 was notably reduced . ^^^ |
|
| Interacting proteins: P18847 and P15336 |
Pubmed |
SVM Score :0.0 |
| In addition , DNA binding experiments demonstrate that the 170 CRE element displays a clear cell type specific occupation with binding activities for ATF 2 and ATF 3 being specific to Heps . ^^^ |
|
| Interacting proteins: P18847 and P15336 |
Pubmed |
SVM Score :0.0 |
| Induction of ATF 3 by ionizing radiation is mediated via a signaling pathway that includes ATM , Nibrin 1 , stress induced MAPkinases and ATF 2 . ^^^ Via these kinases , IR activates ATF 2 , one of the transcription factors acting on the atf 3 promoter . ^^^ As IR does not enhance ATF 2 phosphorylation in ATM and Nibrin 1 deficient cells , both ATF 2 and ATF 3 seem to play an important role in the protective response of human cells to IR . . ^^^ |
|
| Interacting proteins: P18847 and P15336 |
Pubmed |
SVM Score :0.0 |
| Using in situ hybridization and immunohistochemistry , we compared the expression profile of ATF 3 with those of ATF 2 and c Jun after middle cerebral artery ( MCA ) occlusion . ^^^ |
|
| Interacting proteins: P18847 and P15336 |
Pubmed |
SVM Score :0.0 |
| Inhibition of P p 38 with SB 203580 prevents phosphorylation of ATF 2 , a transcription factor for ATF 3 in LKs . ^^^ |
|
| Interacting proteins: P18847 and P15336 |
Pubmed |
SVM Score :0.0 |
| We found that GDNF has an opposing effect on ATF 2 and ATF 3 expression . ^^^ It dramatically downregulates increased levels of ATF 3 in response to injury , whereas the expression of ATF 2 , which is normally reduced after injury , is completely preserved in GFAP GDNF mice . ^^^ |
|
| Interacting proteins: P18847 and P15336 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P18847 and P15336 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P18847 and P15336 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P18847 and P15336 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P18847 and P15336 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P18847 and P15336 |
Pubmed |
SVM Score :0.0 |
| NA |
|