| METHODS : The tissue samples of 42 primary ovarian epithelial carcinoma , 29 benign ovarian tumor and 11 normal ovarian tissue were used to determine the expression of VEGF , VEGFR 1 , VEGFR 2 , P STAT 1 , P STAT 3 , P STAT 5 and P STAT 6 proteins by immunohistochemical staining . ^^^ In endothelial cells , the expression of VEGFR 1 and P STAT 5 closely correlated with each other , as well as VEGFR 2 and P STAT 3 . ^^^ However , in ovarian carcinoma cells , expressions of VEGF , VEGFR 1 and VEGFR 2 were significantly correlated with P STAT 3 and P STAT 5 , but not with P STAT 1 and P STAT 6 . ^^^ |