| Interacting proteins: P17936 and P08253 |
Pubmed |
SVM Score :0.0 |
| Blockade of the type 1 IGF receptor expression in human prostate cancer cells inhibits proliferation and invasion , up regulates IGF binding protein 3 , and suppresses MMP 2 expression . ^^^ |
|
| Interacting proteins: P17936 and P08253 |
Pubmed |
SVM Score :0.0 |
| Purified human MMPs ( principally MMP 1 and MMP 3 ) degraded IGFBP 3 in solution ; MMP 3 produced a pattern of IGFBP 3 degradation products identical in size to the fragments produced by pregnancy serum . ^^^ Furthermore , the combined addition of antihuman MMP 1 IgG and anti human MMP 3 IgG to rat pregnancy serum blocked almost completely the degradation of 125I rhIGFBP 3 , suggesting that these two MMPs are the principal MMPs involved in IGFBP 3 degradation in rat pregnancy serum . ^^^ |
|
| Interacting proteins: P17936 and P08253 |
Pubmed |
SVM Score :0.0 |
| The differences in levels of MMP 1 , IGFBP 2 , IGFBP 3 , and IGFBP proteolytic activity were quantified using densitometric analyses of the ASM tissue extracts that were separated on sodium dodecyl sulfate polyacrylamide gel electrophoresis . ^^^ In addition , IGFBP 2 and IGFBP 3 , which we have previously demonstrated to be proteolytic substrates of MMP 1 , were found to be cleaved in asthmatic airway tissue extracts . ^^^ |
|
| Interacting proteins: P17936 and P08253 |
Pubmed |
SVM Score :0.0 |
| MMP 1 and 2 activities increased and IGFBP 3 was degraded in heart hypertrophied by isoproterenol . ^^^ |
|
| Interacting proteins: P17936 and P08253 |
Pubmed |
SVM Score :0.0 |
| Moreover , they produce significant amounts of TGF beta 1 , TGF beta 2 , IGFBP 3 , and MMP 2 proteins . ^^^ |
|
| Interacting proteins: P17936 and P08253 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P17936 and P08253 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P17936 and P08253 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P17936 and P08253 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P17936 and P08253 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P17936 and P08253 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P17936 and P08253 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P17936 and P08253 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P17936 and P08253 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P17936 and P08253 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P17936 and P08253 |
Pubmed |
SVM Score :0.0 |
| NA |
|