Pubmed abstracts for Protein-Protein Interaction search result :


Interacting proteins: P17302 and P27361 Pubmed SVM Score :0.0
TPA treatment ( 10 ng / ml for 30 min ) of WB F 344 rat liver epithelial cells strongly activated p 42 and p 44 ERK 1 and 2 , blocked gap junction mediated fluorescent dye coupling , and induced connexin 43 hyperphosphorylation and gap junction internalization . ^^^
Interacting proteins: P17302 and P27361 Pubmed SVM Score :0.0
These events include alterations in connexin 43 ( Cx 43 ) phosphorylation , disruption of beta actin binding to Cx 43 , and the induced interaction of Cx 43 with the c Src tyrosine kinase , extracellular signal regulated kinase 1 and 2 , and mitogen activated protein kinase phosphatase 1 . . ^^^
Interacting proteins: P17302 and P27361 Pubmed SVM Score :0.0
Dichlorobiphenyl decreases amplitude and synchronization of uterine contractions through MAPK 1 mediated phosphorylation of GJA 1 ( connexin 43 ) and inhibition of myometrial gap junctions . ^^^ The present study examined the hypothesis that inhibition of myometrial gap junctions through MAPK 1 induced phosphorylation of GJA 1 ( connexin 43 ) leads to inhibition of spontaneous phasic uterine contractions by 2 , 2 ' dichlorobiphenyl ( 2 , 2 ' DCB ) . ^^^ Western blotting showed about a 4 . 5 fold increase in phosphorylation of GJA 1 at S 255 , a MAPK 1 site , after exposure to 100 microM 2 , 2 ' DCB compared to untreated and solvent controls . ^^^ Therefore , this study suggests that 2 , 2 ' DCB decreases amplitude and synchronization of uterine contractions mediated through MAPK 1 mediated phosphorylation of GJA 1 and subsequent inhibition of myometrial gap junctions . . ^^^
Interacting proteins: P17302 and P27361 Pubmed SVM Score :0.0
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Interacting proteins: P17302 and P27361 Pubmed SVM Score :0.0
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Interacting proteins: P17302 and P27361 Pubmed SVM Score :0.0
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Interacting proteins: P17302 and P27361 Pubmed SVM Score :0.0
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Interacting proteins: P17302 and P27361 Pubmed SVM Score :0.0
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