| Interacting proteins: P17302 and P05129 |
Pubmed |
SVM Score :0.0 |
| IGF 1 induced phosphorylation of connexin 43 by PKCgamma : regulation of gap junctions in rabbit lens epithelial cells . ^^^ |
|
| Interacting proteins: P17302 and P05129 |
Pubmed |
SVM Score :0.0 |
| The objectives of these studies are to determine how LEDGF controls PKC gamma activity in normal LECs : how this control of PKC gamma regulates the phosphorylation of Connexin 43 , the inhibition of gap junction activity , and the prevention of assembly of gap junctions in LECs . ^^^ In whole cell extracts of N / N1003A cells , co immunoprecipitation assays showed a protein protein interaction between PKC gamma and Connexin 43 . ^^^ In the presence of LEDGF the activation of PKC gamma enhanced the phosphorylation of Connexin 43 by four fold compared to the absence of LEDGF . ^^^ |
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| Interacting proteins: P17302 and P05129 |
Pubmed |
SVM Score :0.0 |
| H2O2 activated PKCgamma was targeted into caveolin 1 and connexin 43 containing lipid rafts , and the PKCgamma phosphorylated the connexin 43 gap junction proteins on Ser 368 . ^^^ |
|
| Interacting proteins: P17302 and P05129 |
Pubmed |
SVM Score :0.0 |
| NA |
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