| Interacting proteins: P17275 and P84022 |
Pubmed |
SVM Score :1.8626681 |
| We provide evidence for off DNA interactions between Smad 3 and both c Jun and JunB accompanied with reduced Smad 3 DNA interactions . 1.8626681^^^ |
|
| Interacting proteins: P17275 and P84022 |
Pubmed |
SVM Score :0.95579352 |
| Finally , we have determined that off DNA interactions between Smad 3 and both c Jun and JunB result in the reduction of Smad3 / DNA interactions . 0.95579352^^^ |
|
| Interacting proteins: P17275 and P84022 |
Pubmed |
SVM Score :0.72047015 |
| We demonstrate that Smad and AP 1 complexes specifically bind to their cognate cis elements and do not interact with each other on DNA , whereas off DNA interactions occur between Smad 3 and both c Jun and JunB . 0.72047015^^^ |
|
| Interacting proteins: P17275 and P84022 |
Pubmed |
SVM Score :0.64038333 |
| Smad 3 interacts with JunB and Cbfa1 / Runx2 for transforming growth factor beta 1 stimulated collagenase 3 expression in human breast cancer cells . 0.64038333^^^ |
|
| Interacting proteins: P17275 and P84022 |
Pubmed |
SVM Score :0.0 |
| Activation of the PAI 1 promoter by TGF beta or prostaglandin F 2 alpha , and transactivation by c Jun or JunB were not inhibited by dominant negative Smad 3 , supporting the specificity of this mutant . ^^^ |
|
| Interacting proteins: P17275 and P84022 |
Pubmed |
SVM Score :0.0 |
| Two JunB SBEs are arranged as an inverted repeat that is transactivated in response to Smad 3 and Smad 4 co overexpression and shows inducible binding of a Smad 3 and Smad 4 containing complex in nuclear extracts from TGF beta treated cells . ^^^ |
|
| Interacting proteins: P17275 and P84022 |
Pubmed |
SVM Score :0.0 |
| In vitro binding studies demonstrate that both Smad 3 and Smad 4 bind all three Jun family members : JunB , cJun , and JunD . ^^^ |
|
| Interacting proteins: P17275 and P84022 |
Pubmed |
SVM Score :0.0 |
| Antisense transfection experiments indicated that c Jun and JunB were involved in the synergistic effect , and endogenous c Jun physically associated with Smad 3 during a combined EGF / TGF beta treatment . ^^^ |
|
| Interacting proteins: P17275 and P84022 |
Pubmed |
SVM Score :0.0 |
| Expression levels of activator protein 1 family members ( c jun , junB , junD , and c fos ) and transforming growth factor ( TGF ) alpha were significantly lower in TPA treated Smad 3 ( / ) skin , cultured keratinocytes , and papillomas , as compared with Smad 3 ( + / + ) controls . ^^^ |
|
| Interacting proteins: P17275 and P84022 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P17275 and P84022 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P17275 and P84022 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P17275 and P84022 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P17275 and P84022 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P17275 and P84022 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P17275 and P84022 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P17275 and P84022 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P17275 and P84022 |
Pubmed |
SVM Score :0.0 |
| NA |
|