| Interacting proteins: P20700 and P17252 |
Pubmed |
SVM Score :0.0 |
| The possibility of PKC beta ( 2 ) being an apoptotic lamin kinase in these cells was further suggested by lamin B 1 bound PKC delta being inactive or only slightly active and by PKC alpha not combining with the lamin . . ^^^ |
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| Interacting proteins: P20700 and P17252 |
Pubmed |
SVM Score :0.0 |
| In particular , we have found that amino acids 200 217 of the CaLB domain are essential for binding lamin B 1 , as a synthetic peptide corresponding to this stretch of amino acids prevented the interaction between the CaLB domain of PKC alpha and lamin B 1 . ^^^ In agreement with the results of other investigators , we have determined that binding of regulatory elements of PKC alpha to lamin B 1 does not require the presence of cofactors such as PS and Ca ( 2+ ) . ^^^ We have also found that the binding site of lamin B 1 for PKC alpha is localized in the carboxyl terminus of the lamin . ^^^ |
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