| Interacting proteins: P17096 and P06493 |
Pubmed |
SVM Score :0.0 |
| Since both human and murine HMGI / Y proteins , similarly to the insect HMGI protein , possess phosphorylation sites for Cdc 2 and MAP kinases that intersperse the AT hook DNA binding motifs , our results may reflect a general mechanism that regulates the properties and function of this class of putative transcriptional regulators . . ^^^ |
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| Interacting proteins: P17096 and P06493 |
Pubmed |
SVM Score :0.0 |
| Concurrently with a reduction in the Cdc 2 kinase activity at the shift to endoreduplication , significant changes were found in the level and mobility of the HMG I / Y protein ; the faster migrating forms were , at least partly , hypophosphorylated . ^^^ Purified maize HMG I / Y protein was found to be phophorylated in vitro by the Cdc 2 kinase and bound efficiently to the gamma zein promoter AT rich tract ( gammaZ AT ) . ^^^ These data suggest that during maize endosperm development transcription and perhaps replication are controlled , at least partly , by the activity of the Cdc 2 kinase and the interplay between histone H 1 and HMG I / Y proteins . . ^^^ |
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| Interacting proteins: P17096 and P06493 |
Pubmed |
SVM Score :0.0 |
| Phosphorylation by casein kinase 2 , Cdc 2 , and other kinases attenuates the DNA binding affinity of HMGI / Y and the extent of perturbation in DNA structure induced by HMGI / Y binding . ^^^ |
|
| Interacting proteins: P17096 and P06493 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P17096 and P06493 |
Pubmed |
SVM Score :0.0 |
| NA |
|