| Interacting proteins: P42680 and P16885 |
Pubmed |
SVM Score :0.0 |
| PLC gamma 2 activation in EMF stimulated cells is mediated by stimulation of the Bruton ' s tyrosine kinase ( BTK ) , a member of the Src related TEC family of protein tyrosine kinases , which acts downstream of LYN kinase and upstream of PLC gamma 2 . ^^^ PLC gamma 2 activation in EMF stimulated cells is mediated by stimulation of the Bruton ' s tyrosine kinase ( BTK ) , a member of the Src related TEC family of protein tyrosine kinases , which acts downstream of LYN kinase and upstream of PLC gamma 2 . ^^^ |
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| Interacting proteins: P42680 and P16885 |
Pubmed |
SVM Score :0.0 |
| The Tec family kinase Btk plays an important role in the regulation of phospholipase C gamma 2 ( PLC gamma 2 ) downstream of the collagen receptor glycoprotein 6 ( GPVI ) in human platelets . ^^^ Tyrosine phosphorylation of PLC gamma 2 by collagen and CRP is not altered in Tec / platelets . ^^^ However , Btk / / Tec / platelets exhibit a greater reduction in PLC gamma 2 phosphorylation than is seen in the absence of Btk , thus revealing an important role for Tec in this situation . ^^^ These results demonstrate an essential requirement for Tec and Btk in platelet activation by GPVI and reveal a functional role for Tec in the regulation of PLC gamma 2 in the absence of Btk . . ^^^ |
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| Interacting proteins: P42680 and P16885 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P42680 and P16885 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P42680 and P16885 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P42680 and P16885 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P42680 and P16885 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P42680 and P16885 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P42680 and P16885 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P42680 and P16885 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P42680 and P16885 |
Pubmed |
SVM Score :0.0 |
| NA |
|