| Interacting proteins: P16885 and P29353 |
Pubmed |
SVM Score :0.63334322 |
| Upon Epo stimulation , the tyrosine phosphorylated PLC gamma 2 was found to be associated with the tyrosine phosphorylated Grb 2 associated binder ( GAB ) 2 , SHC and SHP 2 proteins . 0.63334322^^^ |
|
| Interacting proteins: P16885 and P29353 |
Pubmed |
SVM Score :0.0 |
| Activation of human neutrophils by Mycobacterium tuberculosis H37Ra involves phospholipase C gamma 2 , Shc adapter protein , and p 38 mitogen activated protein kinase . ^^^ Several tyrosine phosphorylated proteins were associated with the PLC gamma 2 precipitates from Mtb stimulated neutrophils , of which pp 46 was characterized as the Shc adapter protein . ^^^ A role for PLC gamma 2 Shc association in the generation of ROI is supported by the observations that stimulation with Mtb causes the activation of p 38 mitogen activated protein kinase ( MAPK ) , a downstream target of the Shc / Ras signaling cascade , and that the effect of genistein on ROI production coincided with its ability to inhibit both PLC gamma 2 Shc association and p 38 MAPK activation . ^^^ Taken together , these results indicate that stimulation of neutrophils with Mtb triggers the tyrosine phosphorylation of PLC gamma 2 and its association with Shc , and that such association is critical for the Mtb stimulated ROI production through activating p 38 MAPK . . ^^^ |
|
| Interacting proteins: P16885 and P29353 |
Pubmed |
SVM Score :0.0 |
| Baseline Lyn PTK activity is substantially reduced , and slg cross linking fails to activate Lyn , Syk , Pl 3 K , PLC gamma 2 , Vav , Shc , and MAPK . ^^^ |
|
| Interacting proteins: P16885 and P29353 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P16885 and P29353 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P16885 and P29353 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P16885 and P29353 |
Pubmed |
SVM Score :0.0 |
| NA |
|