| Interacting proteins: P19235 and P16885 |
Pubmed |
SVM Score :0.0 |
| Here , we analyzed the involvement of phosphatidylinositol ( PtdIns ) 3 kinase in GPI hydrolysis through PLC gamma 2 tyrosine phosphorylation in response to Epo in FDC P 1 cells transfected with a wild type ( WT ) erythropoietin receptor ( Epo R ) . ^^^ |
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| Interacting proteins: P19235 and P16885 |
Pubmed |
SVM Score :0.0 |
| We examined the role of the Src kinase Lyn in phospholipase C gamma 2 ( PLC gamma 2 ) and phosphatidylinositol ( PI ) 3 kinase activation in erythropoietin ( Epo ) stimulated FDC P 1 cells transfected with a wild type ( WT ) Epo receptor ( Epo R ) . ^^^ We showed that two inhibitors of Src kinases , PP 1 and PP 2 , abolish both PLC gamma 2 tyrosine phosphorylation and PI 3 kinase activity in WT Epo R FDC P 1 cells . ^^^ We also demonstrated that Epo phosphorylated Lyn is associated with tyrosine phosphorylated PLC gamma 2 and PI 3 kinase in WT Epo R FDC P 1 stimulated cells . ^^^ |
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| Interacting proteins: P19235 and P16885 |
Pubmed |
SVM Score :0.0 |
| We showed that erythropoietin induced rapid glycosylphosphatidylinositol ( GPI ) hydrolysis and tyrosine phosphorylation of phospholipase C ( PLC ) gamma ( 2 ) in FDC P 1 cells transfected with the wild type erythropoietin receptor . ^^^ |
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