Interacting proteins: P16871 and P52333 |
Pubmed |
SVM Score :0.0 |
In addition , IL 4Ralpha , gamma ( c ) , and Jak 3 , but not IL 2Rbeta or IL 7Ralpha , were expressed in BMMCs . ^^^ |
|
Interacting proteins: P16871 and P52333 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: P16871 and P52333 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: P16871 and P52333 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: P16871 and P52333 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: P16871 and P52333 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: P16871 and P52333 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: P16871 and P52333 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: P16871 and P52333 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: P16871 and P52333 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: P16871 and P52333 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: P16871 and P52333 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: P16871 and P52333 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: P16871 and P52333 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: P16871 and P52333 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: P16871 and P52333 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: P16871 and P52333 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: P16871 and P52333 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: P16871 and P52333 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: P16871 and P52333 |
Pubmed |
SVM Score :0.0 |
In response to IL 7 stimulation , Jak 3 phosphorylation was markedly reduced in both patient cells as well as in COS cells reconstituted with mutant IL 7R alpha . ^^^ |
|
Interacting proteins: P16871 and P52333 |
Pubmed |
SVM Score :0.0 |
In particular , defects in gammac , JAK 3 and IL7RA have been analysed in terms of development of novel diagnostic tools as well as of new therapeutic agents for the treatment of autoimmune diseases and graft versus host disease . ^^^ |
|
Interacting proteins: P16871 and P52333 |
Pubmed |
SVM Score :0.0 |
Mutations in genes required for T cell development : IL7R , CD 45 , IL2RG , JAK 3 , RAG 1 , RAG 2 , ARTEMIS , and ADA and severe combined immunodeficiency : HuGE review . ^^^ Mutations in any of eight known genes : IL2RG , ARTEMIS , RAG 1 , RAG 2 , ADA , CD 45 , JAK 3 , and IL7R cause SCID . ^^^ |
|
Interacting proteins: P16871 and P52333 |
Pubmed |
SVM Score :0.0 |
By examining different strains of mice with targeted mutations , we now observe that the signaling pathway leading from IL 7Ralpha to rearrangement of the TCR gamma locus requires the gammac receptor chain and the gammac associated Janus kinase Jak 3 . ^^^ |
|