| Interacting proteins: P23560 and P16870 |
Pubmed |
SVM Score :0.0 |
| Sorting and activity dependent secretion of BDNF require interaction of a specific motif with the sorting receptor carboxypeptidase e . ^^^ Modeling and binding studies showed interaction of the acidic residues in the BDNF motif with two basic residues in the sorting receptor , carboxypeptidase E ( CPE ) . ( 35 ) S labeling experiments demonstrated that activity dependent secretion of BDNF from cortical neurons was obliterated in CPE knockout mice . ^^^ |
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| Interacting proteins: P23560 and P16870 |
Pubmed |
SVM Score :0.0 |
| New evidence shows that interaction between a motif in the tertiary structure of BDNF and the sorting receptor carboxypeptidase E directs this neurotrophin to the regulated secretory pathway . . ^^^ |
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