Pubmed abstracts for Protein-Protein Interaction search result :

Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
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Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
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Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
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Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
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Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
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Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
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Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
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Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
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Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
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Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
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Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
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Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
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Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.63303216
After correcting for deep abdominal fat accumulation , no significant correlation was observed between indices of carbohydrate metabolism and plasma HDL 2 CHOL levels whereas deep abdominal fat showed significant correlations with HDL 2 CHOL levels ( P less than 0 . 05 ) after correction for indices of carbohydrate metabolism . 0.63303216^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.80042142
In contrast , HDL binding to guinea pig hepatic membranes exhibited a significant positive correlation with dietary fat quantity ( r = . 98 , P < . 001 ) , consistent with a dose response with increasing fat calories . 0.80042142^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :1.1102917
To test this , we used transiently transfected cells and compared the closely related class B scavenger receptors mouse SR BI and rat CD 36 for their ability to stimulate cholesterol efflux as both receptors bind HDL with high affinity . 1.1102917^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.70246905
CD 36 , a receptor for oxidized LDL , also binds HDL and mediates selective cholesteryl ester uptake , although much less efficiently than SR BI . 0.70246905^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
The predominant activity was oxo reductase ( conversion of cortisone to cortisol greater than cortisol to cortisone ) and was higher in omental than subcutaneous fat ( cortisone to cortisol , median 57 . 6 pmol mg 1 h 1 [ 95 % CI 25 . 8 112 . 9 ] vs 0 pmol mg 1 h 1 [ 0 0 . 6 ] , p < 0 . 001 ) . 11 beta HSD 1 oxo reductase activity was further increased ( 127 . 5 pmol mg 1 h 1 [ 82 . 1 209 ] , p < 0 . 05 ) when omental adipose stromal cells were treated with cortisol and insulin . ^^^ INTERPRETATION : Adipose stromal cells from omental fat , but not subcutaneous fat , can generate active cortisol from inactive cortisone through the expression of 11 beta HSD 1 . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
We have previously reported tissue specific alterations in 11 beta hydroxysteroid dehydrogenase type 1 ( 11 beta HSD 1 ) in obese Zucker rats predicting that reactivation of corticosterone is decreased in liver but increased in omental fat . ^^^ Adrenalectomy ( ADX ) of obese animals attenuated weight gain , normalised hepatic 11 beta HSD 1 kinetics by an effect on 5 ( max ) ( 5 ( max ) in sham operated animals , 6 . 6+ / 1 . 1 nmol / min per mg in lean vs 3 . 4+ / 0 . 6 in obese , P < 0 . 01 ; in ADX animals 5 . 9+ / 1 . 1 in lean vs 6 . 9+ / 1 . 8 in obese , NS ) , and reversed the difference in omental fat 11 beta HSD 1 activity ( 18 . 9+ / 4 . 2 % in lean ADX vs 8 . 2+ / 2 . 3 in obese ADX , P=0 . 03 ) . ^^^ Both metformin and rosiglitazone improved insulin sensitivity in obese , but not lean animals , and had no effect on 11 beta HSD 1 activity in either liver or fat . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
We hypothesized that inhibition of 11 beta HSD 1 activity in adipose tissue by GH may alter fat tissue mass through changes in local F concentrations . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
It is possible that a diet with 27 . 5 % energy from total fat including 10 . 1 % energy from monounsaturated fatty acids , P : S ratio 1 . 38 , 120 mg dietary cholesterol , 26 . 0 g dietary fibre per 1000 kcal would modulate the lipid metabolism resulting in a significant reduction in serum total cholesterol , LDL cholesterol and triglyceride with no reduction in HDL cholesterol . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
A higher excretion of dry matter , fat , nitrogen , energy , and total bile acids in ileal effluents ; a lower plasma low density lipoprotein ( LDL ) and total cholesterols ( 12 . 1 % and 9 . 0 % lower respectively ) ; but no change in plasma high density lipoprotein ( HDL ) cholesterol or apolipoproteins A 1 and B were observed in nine subjects with ileostomies when they consumed an oat bran , bread based , high fiber diet ( HFD ) as compared with a wheat flour , bread based , low fiber diet ( LFD ) for 3 wk with a crossover design . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
No significant difference was seen between the oatbran and control diet periods in body mass index , energy or fat intake , or in total cholesterol , LDL and HDL fractions , apolipoprotein A 1 and B levels , or triglyceride levels . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Studies in rat adipocytes and microsomes . 11 beta hydroxysteroid dehydrogenase type 1 ( 11 beta HSD 1 ) catalyzes the interconversion of biologically inactive 11 keto derivatives ( cortisone , 11 dehydrocorticosterone ) to active glucocorticoids ( cortisol , corticosterone ) in fat , liver , and other tissues . ^^^ Using isolated intact liver or fat microsomes , glucose 6 phosphate stimulated 11 beta HSD 1 oxo reductase , and this effect was blocked by selective inhibitors of glucose 6 phosphate transport . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
A novel constraint to hyperphagia . 11 beta Hydroxysteroid dehydrogenase type 1 ( 11 beta HSD 1 ) catalyzes regeneration of active intracellular glucocorticoids in fat , liver , and discrete brain regions . ^^^ Although overexpression of 11 beta HSD 1 in adipose tissue causes hyperphagia and the metabolic syndrome , male 11 beta HSD 1 null ( 11 beta HSD 1 / ) mice resist metabolic disease on high fat ( HF ) diet , but also show hyperphagia . ^^^ We show that 11 beta HSD 1 / mice express lower hypothalamic mRNA levels of the anorexigenic cocaine and amphetamine regulated transcript and melanocortin 4 receptor , but higher levels of the orexigenic melanin concentrating hormone mRNAs than controls ( C57BL / 6J ) on a low fat diet ( 11 % fat ) . ^^^ HF ( 58 % fat ) diet promoted transient ( approximately 8 wk ) hyperphagia and decreased food efficiency in 11 beta HSD 1 / mice and decreased melanocortin 4 receptor mRNA expression in control but not 11 beta HSD 1 / mice . 11 beta HSD 1 / mice showed a HF mediated up regulation of the orexigenic agouti related peptide ( AGRP ) mRNA in the arcuate nucleus which paralleled the transient HF hyperphagia . ^^^ These data suggest that 11 beta HSD 1 in brain plays a role in the adaptive restraint of excess fat intake , in part by increasing inhibitory opioid tone on AGRP expression in the arcuate nucleus . . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
In fat fed rats , HDL were elevated during the night , suggesting a possible stimulation of their synthesis by dietary fat in the intestine . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
In general , the results demonstrated that the respondents were least knowledgeable regarding the prevalence of smoking , the gender differences in high density lipoprotein ( HDL ) cholesterol levels , the influence of body weight on lipids and the recommended percentages of calories from dietary fat . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
The small rise in total cholesterol concentration in response to the high fat diet was accounted for by a rise in HDL cholesterol . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Although total serum cholesterol , HDL cholesterol and triglyceride concentrations did not differ due to type of pork , results indicated that serum LDL cholesterol was lower ( 15 % ) and hepatic cholesterol was greater ( 15 % ) in the high oleic pork , 15 % fat group as compared with the control pork 15 % fat group . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
HDL cholesterol levels are decreased by intakes of low fat , high carbohydrate diets , a high BMI , and lack of activity and increased by intake of dietary fat , alcohol , and physical activity . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Ethnicity was not significantly associated with HDL C or subfractions after controlling for body fat distribution or fasting insulin . . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
No relationship could be found between apo ( a ) , HDL and HDL 2 cholesterol concentration and nutrient intake but HDL and HDL 2 were negatively associated with the proportion of body fat and apo ( a ) weakly with subscapular skinfold thickness . ( ABSTRACT TRUNCATED AT 250 WORDS ) . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
An interaction between fat type and dietary cholesterol was seen for HDL cholesterol concentrations . ^^^ Saturated fat and the pharmacologic level of dietary cholesterol increased plasma HDL concentrations , whereas polyunsaturated fat minimized the dietary cholesterol mediated increase . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Cases with colorectal cancer had significantly ( p less than 0 . 001 ) and substantially lower values of serum total cholesterol and particularly HDL cholesterol , but these associations did not reflect dietary practices , since protein intake and , to a lesser ( and nonsignificant ) extent , saturated fat and dietary cholesterol intake were higher among cases than among controls . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Simvastatin plus a low or high fat diet increased HDL cholesterol by 10 . 0 % and 2 . 9 % respectively ( P = 0 . 003 overall ) and reduced triglyceride concentration by 15 . 9 % and 19 % respectively ( P less than 0 . 001 ) . ^^^ On a high fat diet , simvastatin produced almost no rise in HDL 3 cholesterol whereas on a low fat diet HDL 3 cholesterol was increased by 8 . 8 % with simvastatin . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Nonsignificant differences in serum concentrations of total cholesterol , HDL cholesterol , and triglycerides between weight regainers and weight losers at the end of long term follow up suggest that some kind of adherence to weight reduction regime including physical exercise may favorably affect the lipid profile as well as body fat distribution independently on the body weight regained . . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
We hypothesized that in the absence of other major risk factors for CAD , the men with SI would have reduced plasma levels of high density lipoprotein ( HDL ) and HDL 2 subspecies due to an upper body fat distribution ( waist to hip ratio [ WHR ] ) , hyperinsulinemia , and abnormal postheparin plasma lipoprotein lipase ( LPL ) and hepatic lipase ( HL ) activities . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Overall obesity ( body fat , body fat percentage and body mass index ) or abdominal obesity ( waist / hip ratio , waist / thigh ratio and waist circumference ) and lipid levels [ high density lipoprotein ( HDL ) , low density lipoprotein ( LDL ) , very low density lipoprotein ( VLDL ) , total cholesterol and triglyceride level ] were measured in 1987 / 88 in a random Danish population sample of men and women ( N = 2987 ) , aged 35 , 45 , 55 and 65 yr . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
We have conducted a crossover , randomized , double blind dietary trial that tested the hypothesis that gender influences the response of plasma lipids , in particular high density lipoprotein ( HDL ) cholesterol , to dietary fat plus cholesterol . ^^^ Importantly , women also showed a greater rise in HDL 2 cholesterol concentration with the fat / cholesterol supplement : 0 . 09 versus 0 . 03 mmol / l ( p less than 0 . 01 ) . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Selective breeding of baboons has produced families with increased plasma levels of large high density lipoproteins ( HDL 1 ) and very low ( VLDL ) and low ( LDL ) density lipoproteins when the animals consume a diet enriched in cholesterol and saturated fat . ^^^ To investigate the mechanism of accumulation of VLDL + LDL in plasma of the high HDL 1 phenotype , we selected eight half sib pairs of baboons , one member of each pair with high HDL 1 , the other member with little or no HDL 1 on the same high cholesterol , saturated fat diet . ^^^ HDL 1 phenotype , type of dietary fat , and dietary cholesterol affected plasma cholesterol and apolipoprotein ( apo ) B concentrations , whereas dietary fat alone affected plasma triglyceride and apoA 1 concentrations . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
In HDL , total cholesterol and phospholipid concentrations were greater in pigs fed 40 % of energy as fat than in pigs fed 20 % of energy as fat ( P less than 0 . 01 ) . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Body mass index correlated to baseline values and affected response to diet ; only the leanest women had significant decreases in total , LDL , and HDL 2 cholesterol in response to the low fat diet . . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
The effects of a 2 month dietary treatment ( 1 , 625 + / 177 kcal , 40 + / 2 . 3 % carbohydrate , 35 + / 3 . 7 % fat , 25 + / 2 % protein , polyunsaturated / saturated fat ratio = 1 . 02 + / 0 . 06 ) on the overall composition of serum lipids , lipoproteins and the fatty acid composition of cholesterol esters and phospholipids in very low ( VLDL ) , intermediate ( IDL ) , low ( LDL ) and high ( HDL ) density lipoprotein in 5 patients with primary familial hypertriglyceridemia type 4 were assessed . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
In experiment 1 , the amount of both apoCII and apoCIII began to increase in exoTG and to decrease in HDL after the initiation of fat infusion . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
These data suggest that the observed decrease in HDL cholesterol was not due to a reduction in very low density lipoprotein derived HDL production or to an LPL deficiency , but was consistent with reduction in chylomicron derived HDL formation following dietary fat restriction . . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
The individual milk yield was recorded daily while both the milk ( dry matter , ash , fat and protein ) and some blood parameters ( glucose , triglycerides , albumin , total protein , urea nitrogen , phospholipids , total and HDL cholesterol , calcium , phosphorus and magnesium ) were checked weekly for each subject , by standard analytical methodology . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Although the parameters of liver and fat metabolism occasionally yielded values close to the limit of the normal range , it was particularly favourable to note , that the lipoprotein fraction HDL exhibited a slightly rising tendency , whereas , at the same time , the LDL fraction dropped . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
It is concluded that , in European men and women , fat distribution may be responsible for male / female differences in serum triglycerides but that such conclusions are less clear for HDL , total and LDL cholesterol . . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
The percentage of total mass due to triacylglycerides was progressively higher from HDL 1 and HDL 3 , whereas that of phospholipids , cholesterol and combined fat was progressively lower . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
LDL and HDL became more fluid when health , free living , premenopausal women were fed reduced fat diets with higher proportions of polyunsaturated fatty acids . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Chemical analyses indicated that HDL generally contained proportionately less protein and more triglyceride , free cholesterol and apo E with saturated fat feeding than with CO diet feeding . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Risk of coronary heart disease as assessed by the body mass index , ratios of total cholesterol to HDL cholesterol , and LDL cholesterol to HDL cholesterol , was significantly lower in subjects in rural area 2 , who were agricultural workers with a high degree of physical activity , subsisting on a diet consisting mainly of plant food , despite a higher consumption of coconut , a saturated fat . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
The HITP group reduced their body fat while HDL cholesterol , HDL 2 cholesterol and apoprotein ( apo ) A 1 increased by 8 . 4 % , 30 % and 16 . 9 % respectively ( p less than 0 . 001 ) . ^^^ Body fat of MITP subjects did not change and HDL cholesterol , HDL 2 cholesterol and apo A 1 increased by 5 . 6 % ( p less than 0 . 05 ) , 17 . 1 % ( p less than 0 . 001 ) and 5 . 6 % ( p less than 0 . 05 ) , respectively . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
After estimating the basal serum levels of total cholesterol ( STC ) , triglycerides ( STG ) , high density lipoprotein ( HDL ) and low density lipoprotein ( LDL ) , the patients were given a high cholesterol and high fat breakfast ( containing 32 g fat and 527 mg cholesterol ) for 7 days . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
After the fat load , HDL cholesterol and HDL associated apo A 1 showed a significant decrease in concentration of 35 and 29 % , respectively . ^^^ In the subjects studied , the atherogenic potential of plasma increased in response to an oral fat load , characterized by a decrease in HDL cholesterol and HDL associated apo A I . . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Total plasma cholesterol ( TPC ) concentrations were 16 % lower ( p = 0 . 01 ) in the polyunsaturated fat fed group , and high density lipoprotein ( HDL ) cholesterol concentrations averaged 20 % lower ( p = 0 . 008 ) in this group between 14 and 50 months of age , while plasma apolipoprotein A 1 ( apo A 1 ) averaged 7 % lower ( p = 0 . 06 ) over this age interval in the animals . ^^^ The HDL cholesterol to apo A 1 ratio was found to be significantly lower ( p = 0 . 006 ) in the animals fed the polyunsaturated fat diet . ^^^ The saturated fat fed animals had significantly higher cholesterol concentrations in HDL 1 and significantly lower cholesterol concentrations in HDL 3 , HDL 4 , and HDL 5 . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
These data suggest that even if total fat intake remains at 39 40 en % , many men show lowered LDL cholesterol if saturated fatty acid intake is minimized and that diets high in polyunsaturated fatty acids do not necessarily lower HDL cholesterol concentrations . . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Women with upper body fat obesity had higher systolic blood pressure , total cholesterol , low density lipoprotein cholesterol , triglycerides , and apolipoprotein B and lower levels of high density lipoprotein ( HDL ) and the HDL subfractions 2 and 3 . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
The mechanism ( s ) by which diets containing corn or coconut oil ( 31 % of energy as fat ) totally free of cholesterol or with 0 . 1 % added cholesterol by weight ( 0 . 3 mg / kcal ) affect plasma high density lipoprotein cholesterol ( HDL C ) , apoprotein ( apo ) A 1 levels , apo A 1 kinetics , and hepatic apo A 1 mRNA concentrations were investigated in 26 cebus monkeys . ^^^ Both the type of fat and cholesterol in the diet significantly affected HDL apo A 1 metabolism by decreasing apo A 1 fractional catabolic rate and increasing apo A 1 production rate in the coconut oil fed groups . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
No significant increase in high density lipoprotein ( HDL ) cholesterol was found in the experiments with the standard diet and the low energy diet , but in the high fat high cholesterol diet experiment the HDL cholesterol increased by 19 % and the ratio HDL cholesterol : total cholesterol from 0 . 327 to 0 . 490 . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Variables assessed throughout the study included : body weight and body mass index ; total cholesterol and HDL ; body fat ; and fat distribution as measured both by waist to hip ratio and by CT scan . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
The combination diet and the low fat diet both caused a significant reduction in HDL cholesterol . ^^^ Thus there was no significant change in the HDL ratio for the combination group and a significant decrease in this ratio for the low fat group . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
By two way ( smoking history and coronary heart disease status ) analysis of covariance , smoking history was significantly related only to subcutaneous fat disposition on the chest and abdomen independent of coronary heart disease , while coronary heart disease status was strongly related to plasma levels of insulin C peptide , VLDL , HDL , HDL 2 , and HDL 3 cholesterol , and total and VLDL triglyceride , independent of smoking history . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
The effects of dietary fat quality and cholesterol intake on expression of guinea pig hepatic membrane high density lipoprotein ( HDL ) binding sites were studied . ^^^ HDL cholesterol levels did not differ between the polyunsaturated , monounsaturated , and saturated dietary fat groups . ^^^ Dietary fat quality and dietary cholesterol intake significantly altered HDL binding to hepatic membranes with increased HDL binding to membranes of animals fed polyunsaturated fat and the high cholesterol diet . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
When the cholesterol saturation index of a fasting gallbladder bile specimen was compared to the plasma HDL cholesterol level for individual animals , a significant positive correlation was noted for animals fed polyunsaturated fat , ( r = 0 . 68 ) and for animals fed saturated fat ( r = 0 . 72 ) . ^^^ For any value of HDL cholesterol , however , the cholesterol saturation index was higher in animals fed polyunsaturated fat compared to saturated fat . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Multivariate associations were sought between risk factor levels ( total cholesterol , high density lipoprotein ( HDL ) cholesterol , triglycerides , glucose , and systolic and diastolic blood pressures ) and two sets of anthropometric variables ( four circumferences and six skinfolds ) to select a set of anthropometric indicators of body fat distribution that correlate most highly with risk of disease . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Multiple regression analyses showed that age adjusted BMI was significantly related to high density lipoprotein ( HDL ) cholesterol , low density lipoprotein ( LDL ) cholesterol , Apo A and Apo B , and blood pressure , independently of abdominal fat distribution . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
We explored the interactions between relative weight , adiposity , and preferred sites of fat accumulation in relation to disease risk , as measured by hypertensive status , blood pressure levels , and blood lipid concentrations ( total cholesterol , triglyceride and HDL cholesterol ) . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
When fish oil was substituted for two thirds of either corn oil or coconut oil , exceptional decreases occurred in plasma cholesterol and triglycerides , as well as in HDL cholesterol and apo A 1 concentrations despite the fact that the fish oil diets contained more saturated fat and less polyenes than the corn oil diet . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Because chronic exercise has been shown to augment chylomicron clearance , we measured HDL cholesterol concentrations and plasma triglyceride and retinyl palmitate responses to high ( 140 g ) and low ( 50 g ) fat meals in endurance trained men . ^^^ The magnitude of postprandial lipemia induced by both the high and the low fat meals was uniformly low compared with values reported previously for sedentary men and was not correlated with HDL cholesterol concentrations . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
For the group fed the diet enriched in monounsaturated fat compared to saturated fat , whole plasma and LDL cholesterol concentrations were significantly lower while high density lipoprotein ( HDL ) cholesterol concentrations were not affected . ^^^ For the group fed the diet enriched in polyunsaturated fat compared to saturated fat , both LDL and HDL cholesterol concentrations were significantly lower than in the group fed saturated fat . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
No changes were seen in body weight , body fat , arm muscle circumference , fasting plasma glucose , insulin , growth hormone , triglyceride , nonesterified fatty acids , or HDL cholesterol . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
A low fat diet decreases high density lipoprotein ( HDL ) cholesterol levels by decreasing HDL apolipoprotein transport rates . ^^^ Upon changing from high to low intake of saturated fat and cholesterol the mean HDL C decreased 29 % from 56 + / 13 ( SD ) to 40 + / 10 mg / dl , while apo A 1 levels fell 23 % from 139 + / 22 to 107 + / 22 mg / dl ( both P less than 0 . 001 ) . ^^^ In contrast , within each diet the HDL C and apo A 1 levels were inversely correlated with apo A 1 FCR both on the high fat ( r = 0 . 85 and 0 . 77 , P less than 0 . 001 and = 0 . 002 , respectively ) and low fat diets ( r = 0 . 67 and 0 . 48 , P = 0 . 012 and 0 . 098 , respectively ) but not with apo A 1 TR . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
The Ath 1 gene determines the levels of high density lipoprotein ( HDL ) lipid in response to a high fat diet challenge as well as susceptibility to diet induced atherosclerosis in mice ( Paigen et al . 1987 . ^^^ When challenged with a high fat diet , the susceptible strain C57BL / 6 exhibited a marked decrease in the levels of HDL cholesterol and apolipoprotein A 1 ( apoA 1 ) , the major protein of HDL , whereas the resistant strains C3H and BALB / c maintained high levels of both . ^^^ We conclude that the Ath 1 gene results in a rapid decrease in both HDL lipid and HDL apolipoprotein levels in the susceptible strain in response to the high fat diet and that this is mediated primarily at the level of HDL catabolism . . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Urban Puriscal residents had a significantly lower fitness level ; increased body fat , total cholesterol , and triglyceride levels ; decreased HDL cholesterol in men ; and higher apo B levels in women compared with rural Puriscal residents . ^^^ Puriscal residents consumed less animal fat and more carbohydrate than did Framingham residents , and these differences were associated with a 21 % lower LDL cholesterol level , a 12 % lower HDL cholesterol level , a 29 % lower apo A 1 level , a 25 % higher triglyceride level , a 16 % higher apo B level , and a 17 % smaller LDL particle size . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Further studies of high density lipoprotein ( HDL ) composition , 3 hydroxy 3 methyl glutaryl coenzyme A reductase ( HMG CoA reductase ) activity and 125I labeled human low density lipoprotein ( LDL ) turnover were done in the group fed the low fat diet without added cholesterol / cholic acid . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Psyllium hydrophilic mucilloid ( Metamucil , Procter and Gamble , Cincinnati , OH ) , a bulk laxative , when used as a dietary supplement in combination with a low fat diet , can lower total serum cholesterol and low density lipoprotein ( LDL ) cholesterol , and raise high density lipoprotein ( HDL ) cholesterol in hypercholesterolemic patients . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Mean plasma concentrations of low density lipoprotein cholesterol and low density lipoprotein total mass ( analytic ultracentrifuge ) , and high density lipoprotein ( HDL ) cholesterol and HDL total mass , did not change significantly on exchanging fat type . ^^^ However , HDL 2 cholesterol concentration was 50 % higher and HDL 3 cholesterol concentration was 7 % lower for polyunsaturated compared with monounsaturated fat . ^^^ Mean total mass of HDL 2 was also 23 . 5 % higher and concentration of apolipoprotein B was 5 . 4 % lower on transfer to the polyunsaturated fat diet . ^^^ Contrary to frequent assertions , we find no advantage with respect to plasma HDL concentrations in using predominantly monounsaturated rather than polyunsaturated fats in subjects who consumed reduced fat , solid food diets . . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Although it has been suggested that dietary polyenes lower total plasma cholesterol , including HDL , and that saturated fat increases both these pools of cholesterol , the current data represents the first evidence that a specific saturated fatty acid , i . e . , palmitic acid , may enhance HDL production . . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
The aims of our study were to investigate the effect of dietary palm oil on the levels of lipoprotein lipase , hepatic lipase , fat distribution ( in the aorta and liver ) , and total cholesterol , HDL , LDL , and triacylglycerol levels in young rats ( 70 g body wt ) over a period of 10 weeks . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
To determine the metabolic regulation of the apoproteins of high density lipoproteins ( HDL ) by estrogen and progesterone , 12 ovariectomized and hysterectomized baboons were fed a high cholesterol , high fat diet and were divided into four groups . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Eight items , i . e . total cholesterol ( TC ) , high density lipoprotein ( HDL ) cholesterol , triglyceride , percentage of alpha LP and beta LP , beta LP concentration , lecithin cholesterol acyl transferase ( LCAT ) , and agarose and polyacrylamide gel electrophoresis of both species were assayed before and after feeding a high fat , high cholesterol diet . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Ordinarily , HDL 1 , a fraction of HDL enriched in apoE , is a minor fraction of plasma , but in human subjects and experimental animals eating diets high in fat and cholesterol and in patients with homozygous familial hypercholesterolemia ( HFH ) or CETP deficiency , HDL 1 ( or HDLc ) concentrations in plasma are increased . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
They assume that the relationship between change in adiposity and change in HDL cholesterol in men who have lost fat by running is the same as the cross sectional difference in HDL cholesterol between naturally fat and lean sedentary men . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Percentage body fat and body mass index showed a positive correlation with total plasma cholesterol and plasma triacyglycerol and a negative correlation with percentage HDL cholesterol for males and females . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
In high fat fed compared to low fat fed animals , HTGL activities were higher , and high density lipoprotein ( HDL ) cholesterol concentrations and the percentages of HDL2b were also higher . ^^^ Significantly lower HTGL activities were found in females compared to males fed the low fat diets , and females had a significantly greater proportion of total HDL in the HDL2b subfraction . ( ABSTRACT TRUNCATED AT 250 WORDS ) . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
In animals fed the atherogenic diet containing saturated fat and cholesterol , the injection of both LPS and TNF also resulted in a significant decrease in the CE content of LDL and HDL . ^^^ However , the plasma total cholesterol levels did not change in the animals fed saturated fat and cholesterol because the decrease in CE content of LDL and HDL was offset by an increase in very low density lipoprotein ( VLDL ) CE . ( ABSTRACT TRUNCATED AT 250 WORDS ) . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Baboons from some families have a higher concentration of plasma high density lipoproteins ( HDL ) on a chow diet and accumulate large HDL ( HDL 1 ) when challenged with a high cholesterol and high saturated fat ( HCHF ) diet . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Serum levels of the plant sterols , campesterol and sitosterol , exhibited positive correlations with the polyunsaturated / saturated fatty acid ratio of dietary fat , the linoleic acid contents of plasma and dietary lipids , the amount of dietary plant sterols ( as indicated by fecal output ) , fractional and absolute absorption of dietary cholesterol , and HDL cholesterol , but were inversely related to the overall cholesterol synthesis and VLDL cholesterol . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Boys from populations with higher carbohydrate and lower fat intake had lower low density lipoprotein ( LDL ) cholesterol levels ( univariate regression coefficient ( + / standard error , 0 . 028 + / 0 . 009 mmol / liter for each percent of energy from carbohydrate ; p less than 0 . 01 , n = 13 ) , but they also had higher fasting triglycerides ( 0 . 010 + / 0 . 002 mmol / liter for each percent of energy from carbohydrate ; p less than 0 . 01 , n = 13 ) and lower HDL cholesterol levels ( 0 . 022 + / 0 . 003 mmol / liter for each percent of energy from carbohydrate ; p less than 0 . 001 , n = 13 ) . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Whereas generalized obesity and body fat distribution are associated with lipid levels , fat distribution ( or a characteristic influencing fat patterning ) can be an important determinant of sex differences in levels of triglycerides , HDL cholesterol , and apolipoproteins B and A I . . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
The body mass index , total percentage of body fat , maximal oxygen uptake , diet , and sex were not significant predictors of the HDL 2 level when added to this model , whereas the original variables remained significant predictors . ^^^ We conclude that HDL 2 levels are inversely correlated with truncal fat , plasma insulin levels , and the presence of glucose intolerance and are not independently associated with sex or total body fat . . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Exploratory analyses revealed , for example , associations of the increase in total physical activity with an increase in the HDL C / total C ratio ( r = 0 . 46 ; P less than 0 . 001 ) , and of the change in estimated body fat content with an opposed change in the HDL C / total C ratio ( r = 0 . 40 ; P less than 0 . 001 ) , or an inverse relationship of the change in subcutaneous fat with a change in the HDL 2 C level ( r = 0 . 39 ; P less than 0 . 001 ) . ^^^ Multivariable regression analysis suggested that much of the effect of jogging on HDL C was apparently mediated through a decrease in body fat content . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Progeny of certain baboon sires accumulate lipoproteins in high density lipoprotein 1 ( HDL 1 ) when challenged with a high cholesterol , high saturated fat diet . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Isocaloric substitution of polyunsaturated fat for saturated fat reduces concentrations of total plasma cholesterol and high density lipoproteins ( HDL ) in nonhuman primates . ^^^ The biochemical mechanisms through which polyunsaturated fat lowers plasma HDL concentrations are not well understood but must involve changes in HDL production or HDL clearance from plasma , or both . ^^^ Animals fed polyunsaturated fat at either cholesterol level had lower plasma concentrations of total cholesterol and HDL cholesterol . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
The synthetic low fat diet did not produce HDL C levels as high as those found in mice fed chow , but resulted in similar VLDL / LDL C levels . ^^^ As reported earlier , when consuming a high fat diet C57BL / 6J mice have significantly lower HDL C and apoA 1 levels than C3H / HeJ mice . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
On the soya bean fat diet , high density lipoprotein ( HDL ) cholesterol decreased by 15 % ( range 6 35 % ) and plasma triacylglycerols decreased by 25 % ( range 13 37 % ) . ^^^ Results of the present study show that even when the proportion of total fat in the diet is low , a high intake of linoleic acid lowers both total plasma cholesterol and HDL cholesterol , while a high intake of saturated fat elevates both these lipid fractions . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
We conclude that even normolipidemic obese subjects have greater postprandial lipemia and triglyceride enrichment of HDL after ingestion of a high fat meal . ( ABSTRACT TRUNCATED AT 400 WORDS ) . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
An earlier study has demonstrated a significant relationship between the increase in HDL concentrations and spontaneous changes in food intake , specifically an increased fat intake . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Plasma lipid concentrations and high density lipoprotein ( HDL ) subclass distributions were evaluated in 22 newborn infants nourished with intravenous ( 4 ) fat . ^^^ Based on baseline ( prior to 4 fat ) HDL subclass profiles determined by gradient gel electrophoresis ( GGE ) , infants fell into two classes , one with two or more pronounced peaks within the normal HDL spectrum ( group 1 , 17 subjects ) and the other with highly unusual HDL distribution ( group 2 , five subjects ) . ^^^ HDL cholesterol , however , did not change with 4 fat where mean values for groups 1 and 2 at baseline , 4 low fat and high fat were : group 1 , 31 . 2 + / 7 . 1 , 30 . 0 + / 8 . 8 , and 36 . 6 + / 16 . 7 mg / dl , respectively ; and group 2 , 20 . 0 + / 7 . 8 , 20 . 2 + / 7 . 4 , and 19 . 8 + / 8 . 8 mg / dl , respectively . ^^^ Unlike HDL cholesterol levels that remained constant with 4 fat , apolipoprotein ( apo ) AI concentrations increased significantly : group 1 , 73 . 0 + / 11 . 0 , 88 . 3 + / 15 . 9 , and 93 . 1 + / 21 . 9 mg / dl , respectively ; and group 2 , 31 . 8 + / 10 . 5 , 41 . 0 + / 12 . 8 , and 59 . 3 + / 18 . 5 mg / dl , respectively . ^^^ In group 1 infants , 4 fat is associated with an increase in larger sized particles , particularly in the ( HDL2b ) gge range ; in group 2 there is an increase in ( HDL3b ) gge and ( HDL3c ) gge components and a disappearance of particles that fall outside of the size range of normal HDL . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
This was in agreement with our hypothesis that the total amount of fat in the diet is a determinant of HDL cholesterol . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
However , few significant associations were observed between the proportion of abdominal fat estimated by the waist / hip circumference ratio ( WHR ) and the lipoprotein lipid profile ( r = . 45 and r = . 44 , P less than . 05 with HDL triglyceride ( TG ) and LDL apo B / LDL cholesterol ratio , respectively ) . ( ABSTRACT TRUNCATED AT 250 WORDS ) . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
In the G 2 individuals the percentage of corporal fat had a direct correlation to the blood levels of triglycerides and VLDL cholesterol , and an inverse correlation to the HDL cholesterol blood level . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
As plasma TG and HDL CHOL are negatively correlated , the associations between obesity , the regional distribution of body fat , plasma TG levels , and plasma lipoprotein concentration and composition were studied in a sample of 76 premenopausal women ( 52 obese and 24 non obese ) . ^^^ Partial correlation analyses revealed that both fat mass and abdominal fat accumulation significantly contributed to VLDL TG and HDL CHOL variances . ^^^ After control for WHR , body fat mass showed no significant association with plasma HDL TG levels , whereas the WHR was positively correlated with HDL TG levels ( p less than 0 . 05 ) . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
It should be stressed that both the accumulation of beta VLDL and alterations in HDL ( reduction in typical HDL and an increase in HDL with apo E ) are associated with accelerated atherogenesis in animals fed high levels of fat and cholesterol . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Rabbits fed cholesterol free , low fat , semipurified diets have more cholesterol and protein in serum low density lipoprotein ( LDL ) relative to high density lipoprotein ( HDL ) than rabbits fed Chow diet . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Role of hepatic triglyceride lipase activity in the association between intra abdominal fat and plasma HDL cholesterol in obese women . ^^^ Intra abdominal fat content is an important variable in the association between regional body fat distribution and plasma high density lipoprotein ( HDL ) cholesterol levels . ^^^ These results suggest that the high H TGL activity in obese women with excess deep abdominal fat could be responsible for the reduction in plasma HDL 2 cholesterol levels . ( ABSTRACT TRUNCATED AT 250 WORDS ) . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Within annual age groups , neither plasma LDL cholesterol nor HDL cholesterol were correlated with percent body fat or either of the ' fat pattern ' indices in each sex . ^^^ In 51 children with serial data 5 years apart , changes with age in HDL cholesterol had significant negative correlations with changes in the ' fat pattern ' indices that were independent of changes in percent body fat in the boys , but not in the girls . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Adjustment for differences in body mass index and fat distribution between the centers did not reduce the differences in cardiovascular risk factors between the different centers but instead revealed that serum cholesterol levels were lowest in the centers of southern Europe ( Italy ) and that HDL cholesterol levels were higher . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Extreme high carbohydrate fat restricted diets cause a fall in HDL as well as in LDL , and the decrease in HDL can not be completely prevented by the presence of fibre in the diet . ( ABSTRACT TRUNCATED AT 250 WORDS ) . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Compared to the modified fat diet , the US 74 diet caused an increase in the ratio of total to HDL serum cholesterol , liver microsomal free cholesterol , fecal cholesterol and hepatic microsomal cholesterol 7 alpha hydroxylase activity and a decrease in hepatic microsomal HMGR activity . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
A recent study has established a strong association between the plasma HDL 2 level and the ability to clear dietary fat from the circulation . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Weight reduction and fat restriction can lower blood pressure , help control hyperglycemia , and improve the LDL cholesterol HDL cholesterol ratio . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Untreated mice had small granules of HDL in the hepatocellular cytoplasm , which appeared more pronounced after oral administration of fat . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
As compared with the high carbohydrate diet , the high monounsaturated fat diet resulted in lower mean plasma glucose levels and reduced insulin requirements , lower levels of plasma triglycerides and very low density lipoprotein cholesterol ( lower by 25 and 35 percent , respectively ; P less than 0 . 01 ) , and higher levels of high density lipoprotein ( HDL ) cholesterol ( higher by 13 percent ; P less than 0 . 005 ) . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Twelve subjects ( 6 women , 6 men ) were given 120 g fat orally for 2 h to study its effect on serum high density lipoproteins ( HDL ) , HDL subfractions and apoproteins A 1 and A 2 . ^^^ In conclusion , the response of HDL 2 to fat meal is more pronounced in women than in men and it seems to be dependent on fasting LPL activity which is higher in women than in men . ^^^ Further , the alterations in postprandial composition of HDL subfractions can be modified by the composition of fat meal . . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
To determine whether altered hepatic secretion of HDL is part of the mechanism by which polyunsaturated fat lowers plasma HDL concentration , we have studied HDL secretion in the isolated perfused livers of African green monkeys fed an atherogenic diet containing either safflower oil as the polyunsaturated fat or butter as the saturated fat . ^^^ We conclude that the perfused monkey liver produces a variety of nascent HDL that are relatively unmodified by the post secretory metabolic events which normally occur in blood plasma in vivo , and that livers of polyunsaturated fat fed monkeys secrete fewer plasma HDL precursor particles than do those of saturated fat fed monkeys . . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
There were significant interactions between HDL 1 class and both dietary cholesterol and saturated fat in their effects on other lipoprotein fractions . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Effect of daily intake of carbohydrate , protein and fat on serum levels of HDL cholesterol and apolipoproteins A 1 and A 2 ] . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
A significant effect ( P less than 0 . 05 ) of dietary fat on plasma total and HDL cholesterol was observed between the end of wk 2 and 7 . ^^^ Low fat intake resulted in 17 + / 2 mg / dL lower total cholesterol and 10 + / 1 mg / dL lower HDL cholesterol than the usual fat intake . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
In contrast , a high fat diet ( 75 % fat ) produced a decrease ( P less than . 01 ) in the concentration of VLDL cholesterol and VLDL triglyceride with increases ( P less than . 01 ) in HDL protein concentration and in HDL cholesterol concentrations that arose largely from an increase ( P less than . 001 ) in HDL 2 cholesterol . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Occupation of husband and body mass index were associated with fat distribution and triglycerides and HDL cholesterol . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
This study performed on 146 healthy men aged 30 55 years involved in recreational training for several years has demonstrated a relationship between an approximate metabolic cost of leisure time sports activities with an energy expenditure greater than 5 kcal / min ( greater than 21 kJ ) and the total coronary risk score , % body fat , HDL cholesterol concentration , smoking frequency , and aerobic capacity indices . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
In boys , total and HDL cholesterol changed in parallel , from low values in populations in developing countries with low fat , high carbohydrate diets to high values in affluent populations . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Effects of saturated and polyunsaturated dietary fat on the concentrations of HDL subpopulations in African green monkeys . ^^^ The effect of the type of dietary fat on the concentrations and compositions of high density lipoprotein ( HDL ) subpopulations was studied in groups of African green monkeys consuming 40 % of calories as fat supplied as saturated fat ( P / S = 0 . 3 ) or polyunsaturated fat ( P / S = 2 . 2 ) in the presence of either 0 . 8 mg or 0 . 03 mg cholesterol / kcal . ^^^ Plasma HDL cholesterol concentrations were lower in polyunsaturated fat fed animals . ^^^ Polyunsaturated fat fed animals had lower concentrations of the large , cholesterol rich HDL2b subpopulation , as well as higher concentrations of intermediate size HDL ( HDL2a and HDL3a on the high cholesterol diet ; HDL3a and HDL3b on the low cholesterol diet ) . ^^^ Consistent with the observed fat related redistribution of HDL mass , the saturated fat fed monkeys had higher apo A I / apo A 2 ratios . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
The effects of saturated fat , compared to unsaturated fat , on both VLDL + LDL and HDL cholesterol levels were similar in both lines . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
The relatively high HDL and HDL 2 cholesterol concentrations , low LDL cholesterol concentration , reduced fat intake , increased ratio of dietary polyunsaturated / saturated fat , relatively frequent use of alcohol , and lack of obesity in West Indians accorded with their low SMR from CHD . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
In contrast , the Low Fat diet significantly lowered HDL cholesterol whereas the High Mono diet did not . ^^^ Therefore , a solid food diet rich in monounsaturated fatty acids is equivalent to a low fat , high carbohydrate diet for cholesterol lowering but does not reduce the HDL cholesterol level . . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
We conclude that 8 11 months of exercise training in previously sedentary men enhances fat tolerance and increases HDL cholesterol concentrations by prolonging HDL survival . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
A moderate but highly significant monotonic positive relationship between coffee drinking and both serum total and non high density lipoprotein ( HDL ) cholesterol was observed in men ( p less than 0 . 001 ) even when adjusted for the confounding effects of age , body mass index , smoking , alcohol , and dietary fat and cholesterol intake . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Serum lipid and apolipoprotein levels , distribution and composition of high density lipoprotein ( HDL ) subfractions and lecithin : cholesterol acryltransferase activity were analysed in nine normolipidaemic subjects , in whom a hypertriglyceridaemic state was induced by the acute administration of ethanol ( 40 g ) plus fat ( 70 g ) or of fat only . 2 . ^^^ Triglyceride ( TG ) levels increased by 180 % 4 6 h after fat plus ethanol intake , the hypertriglyceridaemic response being inversely correlated with the basal HDL 2 mass ( r = 0 . 82 ) . ^^^ The flotation rates of both HDL 2 and HDL 3 increased , reaching a maximum 6 8 h after ethanol plus fat intake . ^^^ Changes in HDL properties were evident only when ethanol was given concomitantly with fat . 7 . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
When compared to the high saturated fat diet , the AHA Phase 2 diet significantly reduced total , low density lipoprotein ( LDL ) , and high density lipoprotein ( HDL ) cholesterol , apoB , and apoA 1 levels , and improved the LDL / HDL cholesterol ratio , whereas the intermittent saturated fat diet lowered total and LDL cholesterol and apoB levels , and also improved the LDL / HDL cholesterol ratio . ^^^ When compared to the AHA Phase 2 diet , the intermittent saturated fat diet raised total and HDL cholesterol levels . ^^^ Thus , in these normal volunteers , intermittent saturated fat ingestion , in the context of an overall 30 % fat diet and a 25 % fat diet , did not differ with respect to the effect on improving the LDL / HDL cholesterol ratio . . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
High density lipoprotein ( HDL ) is the major plasma lipoprotein found in mice fed normal laboratory chow containing 4 % fat . ^^^ When female mice from some inbred strains , such as C57BL / 6 , are fed a high fat diet ( 1 . 25 % cholesterol , 15 % fat , and 0 . 5 % cholic acid ) , the levels of HDL cholesterol decrease by about 50 % , and lipid staining lesions form in the aorta within 14 weeks . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
For the postmenopausal women , the low fat diet lowered cholesterol and HDL cholesterol levels , but there were not the same associations with the hormones . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
In addition , fasting and postprandial triglyceride levels were increased ( p less than 0 . 001 and p less than 0 . 05 , respectively ) and high density lipoprotein ( HDL ) cholesterol concentrations were reduced ( p less than 0 . 02 ) when patients with NIDDM ate the low fat , high carbohydrate diet . ^^^ Finally , since low density lipoprotein ( LDL ) concentrations did not change with diet , the HDL / LDL cholesterol ratio fell in response to the low fat , high carbohydrate diet . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Apo A 1 levels were not changed by either diet when compared with the SS diet , but Apo A 2 levels of HDL 2 and HDL 3 were significantly decreased by the low fat diets , and there was no P / S effect . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
HDL cholesterol response to the low fat regimen was influenced by the P : S ratio . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Significant negative correlations between HDL and obesity measured by either BMI or percent body fat were observed in both sexes , but the slope of the relationship was steeper in women . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
In summary , dietary fat and cholesterol affect lipid and lipoprotein levels as well as the particle number and chemical composition of both LDL and HDL . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Feeding a high cholesterol and high saturated fat ( HCHF ) diet raised both LDL ( 1 . 5 fold ) and HDL levels ( 1 . 3 fold ) without changing VLDL levels . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
In order to determine whether male and female mice differed in HDL lipid levels or in atherosclerotic response to a high fat diet , we examined 3 inbred strains which differed in susceptibility to atherosclerosis ; C57BL / 6 , BALB / c , and C3H . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
This finding suggests that dietary fat does not account for the interracial difference in CHD , nor does the cause appear to be due to genetic differences in lipid profiles , as there was no significant difference between values for plasma triglycerides , total cholesterol , high density lipoprotein ( HDL ) cholesterol , apo 1 , apo 2 , apo B or cholesterol ester fatty acids in the cord blood of each racial group . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Regional variation in HDL metabolism in human fat cells : effect of cell size . ^^^ We have observed that plasma membranes from abdominal subcutaneous adipocytes have a greater HDL binding capacity than omental fat cell plasma membranes . ^^^ The uptake of HDL by collagenase isolated fat cells was studied by incubating the cells for 2 h at 37 degrees C with 10 micrograms / ml 125I HDL 2 or 125I HDL 3 . ^^^ The cellular 125I HDL uptake was significantly correlated with adipocyte size and fat cell cholesterol content but not with adipocyte cholesterol concentration . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Adding wheat germ to the high fat cholesterol diet significantly increased high density lipoprotein ( HDL ) cholesterol and the HDL serum cholesterol ratio and lowered the very low density lipoprotein ( VLDL ) triglycerides . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Among women : TG level was predicted best by FFM , upper body fat pattern , age , and diabetes ( explaining 30 percent of TG variance ) ; LDL C level was predicted by age only ( explaining 12 percent of variance ) ; and HDL C level was predicted by body build only ( 8 percent ) . ^^^ Among men : TG level was predicted best by central and upper body fat patterns and diabetes ( 31 percent of variance ) ; LDL C and HDL C levels were not significantly predicted by any of the 11 study variables . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
From the results of this long term study it can be concluded that a moderate fat diet with a P / S ratio of 2 can lower total cholesterol effectively without affecting HDL cholesterol . . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Ratios of HDL to LDL were not altered by dietary fat . ^^^ Thus , dietary beef and soy protein isolate had similar effects on cholesterol concentrations in plasma , LDL , HDL and organs , whether pigs consumed soybean oil or beef tallow as a major fat source . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
The lipoprotein metabolic system involves chylomicrons derived from dietary fat , very low density lipoproteins ( VLDL ) derived primarily from the liver , and high density lipoproteins ( HDL ) . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Lowering the intake of fat to decrease serum cholesterol levels has unknown effects on the proportion of cholesterol in low density lipoprotein ( LDL ) and high density lipoprotein ( HDL ) . ^^^ One year after the subjects had returned to a self selected diet , levels of dietary saturated fat and cholesterol and the plasma LDL / HDL ratio remained significantly below prestudy levels . ^^^ This study and others suggest that a low fat , high carbohydrate diet favorably affects the plasma LDL / HDL proportion by decreasing LDL on a percentage basis 2 1 / 2 to three times more than it decreases HDL . . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Changes in the clearance rate of exogenous fat were directly related to changes in HDL cholesterol level and the HDL 2 subfraction . ^^^ Thus , the rise in HDL cholesterol concentrations after prolonged exercise may be a consequence of enhanced fat clearance . . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Subjects with a higher Brocca index showed increase in total and LDL cholesterol , significant reduction in HDL cholesterol , and increased total cholesterol : HDL cholesterol ratio after high fat diet consumption . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
The association between body fat distribution patterns and cardiovascular disease risk variables ( high density lipoprotein ( HDL ) cholesterol , total cholesterol , diastolic and systolic blood pressures , and fasting blood glucose levels ) was sought in a sample of Mexican American adults who were studied during 1981 1983 in Starr County , Texas . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
After adjustment for smoking , percent body fat , and alcohol , plasma estradiol levels correlated negatively with total cholesterol and low density lipoprotein cholesterol , and testosterone levels correlated positively with apolipoprotein B , while SHBG levels correlated positively with HDL 2 mass and apolipoprotein A 1 . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Relation of alcohol , physical activity , dietary fat and smoking to serum HDL and total cholesterol in young Finnish men . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Other blood variables ( HDL 2 C , HDL 3 C , Apo A 1 , and LCAT ) , % fat , and aerobic capacity ( VO2max ) were measured pre , mid , and post experiment . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Plasma HDL were obtained from subjects fed for six successive long periods on diets consisting of one predominant fat : peanut oil , corn oil , olive oil , soybean oil , low erucic acid rapeseed oil or milk fats . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Our findings indicate that moderate changes in dietary CHO and fat content affect HDL levels , composition and apo A 1 metabolism . . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Fat patterning made a more important contribution to the prediction of triglyceride and HDL levels than did the other behavioral variables ( except for caloric balance ) and , in general , eliminated ethnic differences in lipids and lipoproteins . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Low density lipoprotein apoproteins were heterogeneous until 14 days , as they are in the human fetus , and contained , besides apoprotein B , all the main apoproteins , HDL reached concentrations of 400 mg / 100 ml at 3 and 4 weeks of age , above 3 fold higher than those of chow fed adults , but also 1 . 5 fold higher than those of growing pigs fed a 20 % fat diet , thereby showing a high capacity of the very young animal to synthesize HDL and apoprotein AI in particular . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
By the zonal method , HDL 2 accounted for 27 + / 4 % ( mean + / SEM ) of total HDL mass in subjects on the high fat diet as compared to 16 + / 2 % in subjects fed the high carbohydrate diet ; by GGE , the HDL2b values were 27 + / 4 % and 14 + / 1 % , respectively . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Serum total cholesterol , high density lipoprotein ( HDL ) cholesterol , and triglyceride levels were studied in healthy male and female subjects consuming for one week periods a diet of conventional food ( CF ) providing 42 % of energy as fat , principally butter fat , and then in random order nutritionally complete , defined formula diets of moderate ( 32 % ) to very low ( 1 % ) fat content . ^^^ Low ( 9 % ) and very low ( 1 3 % ) fat formulas reduced HDL cholesterol by as much as 40 % , raised the total : HDL cholesterol ratio by about 20 % and raised serum triglyceride levels by as much as 100 % . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Relative to the corn oil ( polyunsaturated fat ) diet , the coconut oil ( saturated fat ) diet significantly increased total serum cholesterol by 43 % ( P less than 0 . 001 ) by increasing non precipitable cholesterol ( HDL C ) 58 % ( P less than 0 . 001 ) and precipitable cholesterol ( VLDL + LDL C ) 35 % ( P less than 0 . 001 ) . ^^^ The type of dietary fat did not affect the particle size range of each of the the HDL or LDL subpopulations . ^^^ The results indicate that dietary fat markedly modulates the distribution of cholesterol between apo A 1 containing ( HDL and F1 . 20 degrees 9 28 ) and apo B containing ( IDL and VLDL ) lipoproteins without altering the presence of subpopulations based on particle size . . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
The effects of fat modification and fibre supplementation ( diets C and D ) were strongly additive a fall serum cholesterol by 24 29 % , in low density lipoprotein ( LDL ) cholesterol by 31 34 % , and in serum triglyceride by 21 26 % ; and the reduction , by diet C , of the ratio of serum cholesterol to high density lipoprotein ( HDL ) cholesterol by 21 % , and that of LDL cholesterol to HDL 2 cholesterol by 26 % . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Dietary fat , HDL , cholesterol , and coronary disease : one interpretation . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
HDL apoE levels were higher , although HDL apoA 1 levels were lower in LF than in high fat fed rats . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Our data indicate that normolipidemic individuals with high HDL 2 levels in the plasma are able to clear alimentary fat at a faster rate than normolipidemic subjects with low HDL 2 levels . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
The effect of fat feeding ( 100 g of cream ) on the apoA 1 isoproteins distribution has been analyzed by two dimensional gel electrophoresis in the chylomicrons , VLDL , LDL , and HDL isolated from the thoracic duct lymph of patients undergoing lymph drainage for immunosuppression , Isoforms apoA I 3 and apoA I 4 are the most abundant apoA 1 isoproteins in plasma lipoproteins as well as in lymph lipoproteins collected in the fasting state . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
The effects of varying polyunsaturated / saturated ( P / S ) fat ratios on the plasma levels of lipids , lipoproteins , and apolipoprotein A 1 were assessed in six normal healthy subjects ( three males , three females ) with a particular focus on the P / S ratio which would offer optimal concentrations of both low ( LDL ) and high density lipoproteins ( HDL ) . ^^^ Compared to the P / S = 0 . 4 diet , mean plasma total cholesterol fell by approximately 6 and 12 % on the P / S = 1 . 0 or P / S = 2 . 0 diets , respectively ; plasma concentrations of LDL cholesterol , HDL cholesterol , and apolipoprotein A 1 were also decreased on the polyunsaturated fat diets . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Levels of high density lipoprotein ( HDL ) cholesterol were however similar in all the three groups , suggesting that dietary fat intake and nutritional status may not significantly influence HDL cholesterol levels . . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Relationship between lipoproteins including HDL subfractions and the intravenous fat tolerance test . ^^^ There is a positive relationship between the HDL cholesterol concentration and the fractional removal rate k 2 of intravenously administered Intralipid , the intravenous fat tolerance test ( IVFTT ) . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Evaluation of data from cross sectional nutrition and health surveys sometimes yields different results for men and women but usually demonstrates positive correlations of HDL cholesterol levels with total energy intake , alcohol consumption , dietary cholesterol and total and animal fat , and negative correlations of HDL with dietary carbohydrates ( simple sugars ) and , in some instances , plant fats . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Measurements before and at the end of the test period showed that the ingestion of GK had no significant effect on the following : intestinal transit time , faecal wet or dry weight , concentrations of faecal fat , total and individual volatile fatty acids , bile acids , and neutral sterols ; breath hydrogen and methane concentrations ; glucose tolerance ; serum cholesterol , HDL cholesterol , triglycerides and phospholipids ; plasma biochemistry ; haematological indices ; urinalysis parameters . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
A significant positive correlation between HDL cholesterol and both plaque forming cells and hemolysin titres was detected in the groups fed animal fat . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
In normolipidemic humans , the concentration of apo A 1 and apo A 2 , as well as phospholipids , increased in the light subfraction of high density lipoproteins ( HDL 2 ) 4 to 7 h after ingestion of a meal containing 1 . 5 g cream fat per kilogram body weight . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
In the present study we investigated whether a changed fat intake would influence the levels of lipoproteins , especially the HDL fraction , in twenty three regularly conditioning men , aged 30 44 years , with a maximal aerobic capacity of 53 . 4 ml / kg 10 min 1 + / 0 . 8 , mean + / SE . ^^^ The data reveal that these large dietary changes did not influence HDL cholesterol concentrations ( 1 . 71 + / 0 . 10 , 1 . 69 + / 0 . 12 , 1 . 59 + / 0 . 13 mmol / l , mean + / SE , during ordinary , fat rich and fat poor diet , respectively ) and only influenced apo A 1 levels to a minor degree after the fat poor diet ( 134 + / 6 . 1 , 134 + / 7 . 1 and 123 + / 4 . 7 arbitrary units , mean values + / SE ) during ordinary , fat rich and fat poor diet , respectively ) . ^^^ These findings show that large variations in the intake of dietary neutral fat only to a minor extent influence the level of HDL cholesterol and apo A 1 in physically active subjects . . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Lipid lowering diets enriched in polyunsaturated fat decrease the serum cholesterol in hyperlipoproteinaemia , usually by reducing both the low density lipoprotein ( LDL ) and high density lipoprotein ( HDL ) cholesterol concentrations . ^^^ The aim of the present study was to investigate whether the effects on LDL could be maintained but those on HDL cholesterol be diminished by reducing the ratio , polyunsaturated : saturated fat ( P : S ) of the diet . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
A negative relationship was evident between the level of total cholesterol and that of HDL and between the latter and the amount of fat consumed . . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
The younger individuals had greater fat to protein ratios in the HDL 1 and HDL 2 subfractions . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
It is concluded that a low fat , high P / S ratio diet lowers LDL and HDL 2 cholesterol in healthy volunteers , but does not influence the level of HDL 3 subfraction . . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
There was a reduction in the hepatic triglyceride lipase activity but no change was seen in serum triglycerides , serum cholesterol , serum LDL , serum HDL , peripheral lipoprotein lipase activity and the intravenous fat tolerance test . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Total parenteral nutrition with fat emulsions obtains good results in the normalization of plasma lipoproteins and fatty acid distribution by influencing the composition of VLDL , LDL , and HDL . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Changes in percent body fat and in HDL cholesterol were correlated ( r = 0 . 47 ) in runners . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Total triglycerides increased modestly ( 15 % ) and high density lipoprotein ( HDL ) cholesterol fell significantly ( 14 % ) on replacement of 40 % fat with 30 % fat . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Monkeys fed polyunsaturated fat had significantly lower plasma cholesterol ( 186 + / 18 vs . 276 + / 31 mg / dl ) and high density lipoprotein ( HDL ) mass concentrations ( 466 + / 28 vs . 518 + / 34 mg / dl ) than did animals fed saturated fat . ^^^ In vivo reinjection studies , using thoracic duct lymph chylomicra labeled with ( 131 ) 1 and HDL labeled with ( 125 ) 1 , were done in order to study the mechanism of plasma HDL lowering by polyunsaturated dietary fat . ^^^ There was a consistent trend toward a higher FCR for HDL apoA 1 or A 2 of polyunsaturated fat fed recipients . ^^^ It was concluded that : ( 1 ) dietary polyunsaturated fat significantly lowered plasma cholesterol , HDL , and apoA 1 concentrations relative to saturated fat ; ( 2 ) the HDL lowering effect of the dietary polyunsaturated fat may be due to the combined effects of decreased apoprotein production by the intestine and increased HDL catabolism ; and ( 3 ) in the blood , chylomicron apoA 1 and A 2 differ in their metabolic fates . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
After oral fat , an initial fall and a subsequent rise in apoCII and CIII in HDL was associated with reciprocal changes in apoC concentrations in very low density lipoproteins . ^^^ We speculate from the data that 1 ) plasma HDL and their apoC concentrations are important determinants of chylomicron clearance and 2 ) transfer of apoCs from HDL to triglyceride rich lipoproteins in the early phase of fat absorption does not result in the total recycling of apoCs from these lipoproteins to HDL during the late phase of alimentary lipemia . . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Fasting plasma triglycerides ( TG ) , HDL cholesterol , total cholesterol ( TC ) , and percent body fat ( % BF ) were measured in women ages 24 58 yr . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
These findings suggest that increasing the concentrations of both dietary cholesterol and total fat can increase the levels of plasma LDL , HDL 2 , and HDLC in fasting normal subjects . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
However , HDL was depressed by the low fat diet in comparison with diets with a higher fat content , whether high or low in polyunsaturates . ^^^ This suggests that `` Western ' ' diets , usually high in fat , elevate both total and HDL cholesterol concentrations in children and young adults . . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Body mass index ( BMI ) , percentage body fat , and serum values for Trig , TC , HDL , and HDL / TC were constant throughout the observation period . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Diet B ( low cholesterol , high polyunsaturated fat ) caused significant decreases in plasma cholesterol , LDL cholesterol and HDL cholesterol of 17 . 0 , 16 . 2 , and 17 . 4 % , respectively , in 12 normal subjects ; and reductions of 11 . 0 , 10 . 8 , and 17 . 1 % , respectively , in 19 hypercholesterolemic subjects . ^^^ Diet C ( low cholesterol , very low fat ) produced significant mean decreases in plasma , LDL , and HDL cholesterol of 26 . 7 , 29 . 9 , and 27 . 9 % , respectively , in 11 normal subjects , and in nine hypercholesterolemic patients of 22 . 6 , 27 . 2 , and 28 . 6 % , respectively . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
We examined the effects of dietary cholesterol ( less than 0 . 01 and 1 . 7 mg / Kcal ) and type of fat ( saturated , coconut oil ; polysaturated , corn oil ) on very low density plus low density lipoprotein ( VLDL + LDL ) and high density lipoprotein ( HDL ) cholesterol in 24 young baboons ( 12 male , 12 female ) Paplo sp . ) in a crossover design experiment . ^^^ There was a significant interaction between cholesterol and type of fat in their effects on VLDL + LDL cholesterol , but not in their effects on HDL cholesterol . ^^^ Saturated fat consistently elevated HDL cholesterol more than did dietary cholesterol . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
A significant interaction of infant diet ( breast vs formula ) with type of fat ( saturated vs unsaturated ) at 4 6 years of age was observed on HDL cholesterol and apolipoprotein A 1 ( apoA 1 ) concentrations . ^^^ That is , animals breast fed as infants had higher HDL cholesterol and apoA 1 concentrations when fed unsaturated fat from weaning to 4 6 years of age than those fed saturated fat ( 77 vs 68 mg / dl ) . ^^^ In contrast , animals fed formulas in infancy followed by a diet containing unsaturated fat had lower HDL cholesterol and apoA 1 concentrations at 4 6 years of age than did those fed saturated fat ( 67 vs 78 mg / dl ) . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
When the relationship between dietary factors and the HDL cholesterol / cholesterol ratio was examined the most important dietary factor appeared to be saturated fat , which was negatively associated with this ratio . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
The relation of HDL 2 to fitness was independent in body fat and basal plasma insulin level ; in addition the relationship between HL and fitness was not accounted for by body fatness . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
It is considered that the diet of pupils ( inter alia , having low fat and high fibre contents ) , associated with the high level of activity which prevails generally , share responsibility for their high HDL cholesterol levels . . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
The disappearance rate of intravenously administered fat emulsion ( which corresponds to the clearance rate of chylomicrons and VLDL ) was diminished in azotaemic patients , showing a significant inverse correlation between HDL cholesterol and disappearance rate in the intravenous FTT . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Most investigators believe that a specific therapy of the hypercholesterolaemia and hypertriglyceridaemia of patients with nephrotic syndrome is not necessary since the disturbances in fat metabolism are associated with an increased levels of HDL cholesterol . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
In boys , the RBW and percentage of body fat were also positively associated with total lipids , VLDL and negatively associated with HDL . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Saturated fat feeding also resulted in th saturation of fatty acids of triglycerides and cholesteryl esters of VLDL and LDL , but had little effect on HDL fatty acids . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Hypertriglyceridaemia is the most common lipid abnormality in patients with renal failure and a long term fat modified diet is , therefore , of limited therapeutic importance in these patients unless there is a low HDL / LDL cholesterol ratio . . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Feeding of the high fat diet was found to increase plasma triglycerides , cholesterol and phospholipids , but also to enlarge the pool of HDL lipoproteins by 46 % and 50 % in the control and cold environment , respectively . ^^^ The HDL pool increased by 43 % in animals fed the control diet and by 47 % in the fat fed . ^^^ The effects of diet and environment were additive and resulted in a 113 % increase in the HDL pool of fat fed rats exposed to 5 degrees C over that of rats fed the low lipid diet at 22 degrees C . ^^^ This was accompanied by a reduction in the size of the HDL pool which was significant ( p less than 0 . 05 ) in the rats fed the high fat diet . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
The effect of the type of dietary fat was that total plasma cholesterol ( TPC ) and HDL cholesterol concentrations were lowest while the safflower oil diet was fed , were significantly higher when butter fat diets were fed , and were highest when the egg yolk lard based diets were fed . ^^^ In addition , a significant effect of the elevated level of dietary cholesterol , independent of the type of dietary fat , was seen : a statistically significant negative correlation between TPC and HDL cholesterol concentrations was induced . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Since diets containing a high P / S ratio have been reported to have detrimental effects on HDL , the effect of a moderately modified fat diet ( P / S ratio 1 . 0 , cholesterol content 250 mg / day ) was investigated in 30 healthy male volunteers , divided into 2 groups . ^^^ We conclude that a moderately modified fat diet supplied from mixed general food is acceptable for longer periods , effectively lowers LDL cholesterol , even in normolipoproteinemic subjects , and has no detrimental effects on HDL . . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Isocaloric changes in dietary carbohydrate and fat cause significant alterations in plasma levels of VLDL and HDL 2 , the two major lipoproteins that transport apoC 3 and apoC 2 . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
A survey of factors that influence HDL levels suggests that the higher AI levels were due to changes in diet , including fat and alcohol consumption . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Life style variables ( perceived fitness , excess body mass , percent fat , lean mass , predicted maximum oxygen intake , cigarette consumption , alcohol consumption , use of contraceptive medication ) have been related to the lipid profile ( serum triglycerides , total cholesterol , HDL and LDL cholesterol ) in a sizeable volunteer population of Toronto office workers . ^^^ Much of the fitness effect is related to body fat , which is positively correlated with triglycerides and ( in the men only ) with total and LDL cholesterol , but is negatively related to HDL cholesterol . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Eighty males ranging in age from 21 to 75 years were examined for maximal aerobic capacity ( VO2max expressed in ml / kg 10 min 1 ) , serum cholesterol ( total , HDL , LDL , and VLDL cholesterol ) , serum triglycerides , body fatness ( % ) and dietary patterns including total and constituent ( protein , fat and carbohydrate ) kilocalories and dietary cholesterol and alcohol intake . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Since Apoprotein A 1 ( apo A 1 ) is partially synthesized in the intestine and is secreted into plasma via chylomicrons , we have tested the effects of the daily distribution of fat intake on the concentration and composition of plasma high density lipoprotein ( HDL ) . ^^^ These results indicate that HDL apo A 1 increases when fat intake is distributed throughout the day ( DL ) , perhaps due to intestinal production of particles with a higher protein / lipid ratio during DL than after a large bolus of oral lipid ( SL ) . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Dietary saturated , monounsaturated and polyunsaturated fat intakes were unrelated to HDL cholesterol levels ; similarly , no association was seen for HDL cholesterol and total calories and total fat . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
HDL cholesterol was positively correlated to lipoprotein lipase ( r=0 . 50 , p < 0 . 05 ) and to the fractional removal rate of exogenous fat ( r=0 . 59 , p < 0 . 01 ) , and negatively to the fasting levels of triglycerides ( r= 0 . 65 , p < 0 . 01 ) . ^^^ LCAT was neither correlated to HDL cholesterol nor to the fat removal rate . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Prudent diets in patients with type 2 and 4 hyperlipoproteinemia had no significant effects on HDL cholesterol within 3 weeks , whereas in normal individuals , a high carbohydrate diet given for 10 days caused significant decreases in HDL cholesterol with concomitant increases in HDL triglycerides as compared to a high fat diet . ^^^ The HDL triglyceride fatty acid composition changed in healthy volunteers during the day , depending on the type of ingested fat . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
HDL cholesterol and intravenous fat tolerance in dialysis patients . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Pigeons ( Sham , LoLo , HiHi ) fed the cholesterol saturated fat diet circulated HDL with greater free and esterified cholesterol mass than Controls . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
HDL cholesterol levels , however , were unaffected by source of fat fed . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Fat distribution was also negatively correlated with HDL 2 cholesterol ( r = . 20 , P < 0 . 05 ) . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Plasma HDL cholesterol concentrations were comparable in animals fed saturated and monounsaturated fat and were significantly higher than in animals fed polyunsaturated fat . ^^^ Thus , the monounsaturated fat group had the lowest LDL / HDL ratio . ^^^ The beneficial effects of the lower LDL and higher HDL in the animals fed monounsaturated fat apparently were offset by the atherogenic shifts in LDL particle composition . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
After adjustment for body fat mass , women generally displayed a more favourable risk profile than men which included higher plasma HDL 2 cholesterol and lower plasma insulin , apolipoprotein B and triglyceride levels ( p < 0 . 01 ) . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Neither type of unsaturated fat significantly changed HDL cholesterol or triglyceride levels relative to the high saturated fat diets . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Although stearic acid ( 18 : 0 ) is typically considered neutral , exaggerated consumption of 18 : 0 rich fat ( cocoa butter ) lowers both LDL and HDL . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
METHODS AND RESULTS : We conducted multivariate genetic analyses to detect the effects of genes and environmental factors on variation in plasma concentrations of HDL C and TG , fat mass ( as percent body weight [ FM % ] , determined by bioelectric impedance ) , and body mass index ( BMI ) . ^^^ Likelihood ratio tests disclosed significant heritabilities ( P < . 001 ) for all traits ( h2HDL C = 0 . 55 , h2TG = 0 . 53 , h2FM % = 0 . 37 , h2BMI = 0 . 44 ) but significant genetic correlations ( P < . 001 ) , indicating pleiotropy , between two trait pairs only : HDL C and TG ( PG = 0 . 52 ) and fat mass and BMI ( PG = 0 . 86 ) . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
In hamsters fed a coconut fat supplemented diet , Ro 16 6532 reduced all lipoproteins , with a stronger effect on VLDL and LDL than on HDL cholesterol . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Animals fed the high fat diet plus lovastatin had significantly lower levels of non high density lipoprotein ( HDL ) cholesterol than those fed the unsupplemented high fat diet . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
When this is replaced by saturated fat , the plasmatic levels of LDL fall while those of HDL remain constant or even increase . ^^^ The substitution of saturated fat by PUFA , n 6 , lowers LDL levels and also HDL levels if these fatty acids are consumed in quantity . ^^^ When saturated fat is replaced by n 3 fatty acids the effect on LDL and HDL are variable , and there is a substantial decrease in VLDL . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
In conclusion , in an NCEP Step 1 diet containing 30 % total fat , with all other known cholesterol influencing dietary factors held constant , the substitution of polyunsaturated fatty acid for monounsaturated fatty acid from 3 % to 14 % resulted in a progressive decline in total cholesterol and less triacylglycerol elevations , without effect on HDL cholesterol . . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
In both species , cholesterol concentrations in whole plasma , LDL , and high density lipoprotein ( HDL ) were 20 30 % lower when polyunsaturated fat was fed , whereas dietary cholesterol increased LDL cholesterol three to fourfold . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Stable B subjects had significantly greater increases in the largest very low density lipoprotein subfraction with the low fat diet than the stable A group , and also had greater decreases in the high density lipoprotein ( HDL ) subclass HDL 3 but smaller reductions in HDL 2 . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
However , adjustment for body weight and body fat distribution weakens the association between SHBG , testosterone and HDL cholesterol . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
In response to dietary fat and cholesterol supplementation only the changes in HDL cholesterol , especially in HDL 2 , differed between the sexes . ^^^ These studies explain much of the variability that individuals show in lipoprotein changes , especially in the more desirable changes in cholesterol transport in HDL 2 , in response to eating saturated fat and cholesterol . . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
A nonsignificant trend toward a greater change in HDL C in women existed after adjustment for baseline percent body fat and estimated METs . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
In 68 men aged 43 . 8 + / 7 . 4 years from a sample of managers of a Prague bank the case history we evaluated , as well as a basic physical examination , a loading test on a bicycle ergometer ( performance evaluated in W / kg body weight or lean body mass ) and ECG ; serum lipids were examined ( total and HDL cholesterol , triacyglycerols ) , the body mass index ( BMI ) , the ratio of depot fat ( by evaluation of 10 skinfolds measured by means of a caliper ) and the distribution of body fat ( indices relating either only the subscapular and tricipital skinfold or all skinfolds on the trunk to all skinfolds on the extremities , and the waist / hip ratio ) . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Substitution of carbohydrates by fat will increase the level of HDL cholesterol but decrease that of fasting serum triglyceride . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
OBJECTIVE : The study was designed to compare , in a homogeneous , normolipidemic population , the postprandial responses of plasma lipids , in particular , high density lipoprotein ( HDL ) constituents , after administration of a polyunsaturated fat and a more saturated fat . ^^^ Similar increases in HDL constituents at 7 10 hours after CO or BT , despite the difference in TG responses , suggests differences in the metabolism of chylomicrons and / or HDL due to the type of fat ingested . . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Rats fed the high cholesterol / high fat diet had lower HDL cholesterol concentration than groups fed the other base diets . ^^^ Fish oil lowered HDL triglycerides only in rats fed the low fat diet without cholesterol . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
We have previously described the ability of polyunsaturated fat diets to lower plasma described the ability of polyunsaturated fat diets to lower plasma high density lipoprotein ( HDL ) cholesterol levels and alter HDL subpopulation distribution in the primate model . ^^^ Animals fed polyunsaturated fat had significantly lower plasma concentrations of HDL cholesterol , total plasma cholesterol , and apolipoprotein A 1 . ^^^ These data demonstrate that differences in dietary fat intake can significantly alter HDL PC concentration and molecular species distribution . ^^^ We also propose that dietary n 3 Poly affects cholesteryl ester metabolism in part via LCAT by lowering PC ( LCAT substrate ) availability , altering the rate of the LCAT reaction , and decreasing HDL cholesterol concentrations ; however , n 6 Poly dietary fat effects on HDL concentration appear to be through some mechanism other than LCAT . . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
If any fat is replaced by carbohydrates , fasting triglyceride values rise and HDL concentrations fall ; effects on LDL depend on the type of fat that is being replaced . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
In Mediterranean diets the major source of dietary fat has traditionally been olive oil , which , compared with saturated and partially hydrogenated fats , reduces low density lipoprotein ( LDL ) cholesterol and , compared with carbohydrates , increases high density lipoprotein ( HDL ) cholesterol . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
We examined the effects of replacing dietary fat with carbohydrates on high density lipoprotein ( HDL ) subclasses as measured by nondenaturing polyacrylamide gradient gel electrophoresis . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
To study dietary fat and cholesterol effects on plasma high density lipoprotein ( HDL ) metabolism and rates of apolipoprotein ( apo ) A 1 catabolism , guinea pigs were fed 15 % ( wt / wt ) lard or corn oil based diets with 0 . 01 % ( basal ) , 0 . 08 % , 0 . 17 % or 0 . 33 % cholesterol . ^^^ Fractional catabolic rates ( FCR ) of injected [ 131I ] apo A 1 were not altered by dietary treatment , either fat saturation or cholesterol , but were inversely correlated with plasma EoHDL cholesterol levels ( r = 0 . 622 ) , suggestive of a regulatory role of turnover rates on HDL cholesterol levels independent of dietary treatment . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Compared with the baseline diet , the low fat , high fiber diet resulted in significant decreases in total cholesterol ( TC ) , low density lipoprotein ( LDL ) cholesterol , and high density lipoprotein ( HDL ) cholesterol concentrations during both the follicular and luteal phases ( TC , 14 % and 16 % ; LDL cholesterol , 14 % and 17 % ; and HDL cholesterol , 15 % and 18 % , respectively ) . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Centralized fat distribution was positively associated with blood pressure and glucose , triglyceride , and apolipoprotein ( apo ) B levels , and negatively associated with high density lipoprotein ( HDL ) cholesterol and apo A 1 levels in this population . ^^^ Body fat distribution had an effect independent of body mass index and accounted for some of the differences in triglyceride , HDL cholesterol , apo A 1 , and apo B concentrations among men , premenopausal women , and postmenopausal women . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
The changes in ApoA 1 and HDL cholesterol were greater in patients whose fat mass increased significantly . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Further , several findings between specific risk parameters smoking , calories from fat , blood pressure , and cholesterol level ( HDL ) were significantly associated with different dimensions of the control profile . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
To study the mechanism of HDL elevation by saturated fat , male rats and male mice were employed as animal models , since they also raise their plasma HDL levels when fed high lipid diets . ^^^ However , the high fat diet increased HDL levels by 20 % in rats and 55 % in mice . ^^^ A combination of saturated fat and cholesterol diet raised plasma HDL levels by 36 and 67 % in rats and mice , respectively . ^^^ Mechanism of HDL elevation by saturated fat was investigated . ^^^ Additional regulation through impaired catabolism of HDL particles by high fat diet feeding may be another pathway for increased HDL levels . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
In response to a diet containing high fat and high cholesterol , HDL cholesterol was doubled in the mutants , but was slightly decreased in the wild type mice . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
In men , the lowest LDL / HDL ratio was achieved with simvastatin on a low fat diet ( 22 % energy ) . ^^^ Gender differences in the effect of simvastatin on HDL were confined to HDL 3 cholesterol , although the drug raised HDL 2 in both sexes on the low fat diet . ^^^ Simvastatin was responsible for an 11 % increase in HDL 3 cholesterol in men particularly when on a low fat diet but did not affect HDL 3 in women . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Total , LDL , and HDL cholesterol , as well as LDL apo B , HDL apo A 1 and HDL total apo C concentrations , were reduced with the mono and polyunsaturated fat diets relative to the saturated fat diet . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
A low fat diet reduced mean body weight by 2 kg without significantly altering blood lipids ( total and HDL cholesterol , triglycerides ) . ^^^ However , its ability to increase HDL cholesterol may be reduced in patients on low fat diets . . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Significant correlations emerged between body mass index and sum of glucose during oral glucose load and HDL 3 triglycerides and also between visceral abdominal fat and triglycerides , apolipoprotein B , sum of insulin during oral glucose load , very low density lipoprotein ( VLDL ) cholesterol , and VLDL and low density lipoprotein ( LDL ) triglycerides . ^^^ Visceral abdominal fat correlated negatively with the ratio of HDL to LDL cholesterol . ^^^ When the subjects were subdivided into four groups according to body mass index ( < or = 26 . 7 , > 26 . 7 ) and median visceral abdominal fat , no significant differences were found in body mass index , whereas significant differences were found for triglycerides , cholesterol , apolipoprotein B , VLDL cholesterol , HDL : LDL cholesterol , and VLDL triglycerides . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
MEASUREMENTS : Fasting concentrations of plasma free fatty acids , serum cholesterol and triglycerides in high density lipoproteins ( HDL ) , low density lipoproteins ( LDL ) and very low density lipoproteins ( VLDL ) in relation to insulin sensitivity index ( M / I ; assessed with the euglycaemic insulin clamp ) , glucose tolerance ( k value ; intravenous glucose tolerance test ) , basal serum hormone concentrations , and body fat distribution ( skinfolds and waist hip ratio ) . ^^^ Stepwise regression analysis for the total population , comparing endocrine , anthropometric and metabolic explanatory variables , showed that the serum levels of HDL cholesterol and triglycerides were mainly correlated with body fat distribution ( both ) and fasting insulin levels ( triglycerides ) , and levels of total and LDL cholesterol with BMI and age . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Our purpose was to elucidate the mechanisms whereby diets high in polyunsaturated fat lower plasma triglycerides and HDL cholesterol concentrations compared with diets high in saturated fat . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
There were significant differences in age , blood pressure , rate of body fat , blood glucose , total cholesterol , HDL cholesterol , and index of arteriosclerosis between above 50 and below 50 in the new APG index . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
After cardiac rehabilitation and exercise training , patients had improvement in total cholesterol , triglycerides , high density lipoprotein ( HDL ) cholesterol levels , low density lipoprotein ( LDL ) cholesterol levels , LDL / HDL ratios , body mass index , percent body fat , and METs . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Women with IGT had more thoracic subcutaneous fat and intra abdominal fat and lower fasting HDL cholesterol than women with normal glucose tolerance , and tended to have higher fasting triglyceride and LDL cholesterol . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Our aims were 1 ) to examine the effects of a high carbohydrate low fat diet on fasting and postprandial plasma lipids , apolipoproteins ( apo ) , and lipoprotein composition in noninsulin dependent diabetes mellitus , and 2 ) to determine whether postprandial shift of apo between triglyceride rich lipoproteins ( TRLP ) and high density lipoproteins ( HDL ) is affected by diet . ^^^ We conclude that 1 ) a high carbohydrate diet results in a decrease in total , LDL , and HDL cholesterol and a trend toward an increase in plasma triglycerides ; 2 ) fasting TRLP and HDL apo composition was similar on a high carbohydrate or a high fat diet ; and 3 ) on both diets , apo CII , CIII , and E transfer from HDL to TRLP postprandially . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
High density lipoprotein ( HDL ) levels were not influenced by fat saturation or cholesterol level ; however , HDL was higher with addition of cholesterol to corn oil versus beef tallow ( P < 0 . 02 ) . ^^^ However , with the exception of HDL levels , dietary fat saturation and cholesterol levels do not interactively influence circulating lipoprotein cholesterol levels and cholesterol synthesis . . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Multiple stepwise regression models were performed in which cardiovascular risk factors ( total , LDL and HDL cholesterol , triglycerides , fasting and postprandial blood glucose , systolic and diastolic blood pressure ) were considered as the dependent variable and age , sex , smoking habits , body mass index ( BMI ) , waist circumference ( WC ) , waist hip ratio ( WHR ) , subscapular / tricipital skinfold ratio ( STR ) and percentage of total body fat ( % BF ) , derived from the sum of four skinfolds , as the independent variables . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Compared with 12 nonischemic controls of comparable age , percent body fat , and VO2max , the 13 men with SI had decreased fasting HDL cholesterol ( [ HDL C ] 41 + / 2 5 50 + / 2 mg / dL , P < . 001 ) and % HDL2b subspecies levels as measured by gradient gel electrophoresis ( 22 + / 2 5 34 + / 3 , P < . 001 ) . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
The level of high density lipoprotein ( HDL ) cholesterol fell by 6 percent ( 95 percent confidence interval , 4 to 8 percent ) during the low fat diet ( P < 0 . 001 ) and rose by 4 percent during treatment with lovastatin ( P < 0 . 001 ) . ^^^ The ratio of LDL to HDL cholesterol and the level of total triglycerides were reduced by lovastatin ( P < 0 . 001 ) , but not by the low fat diet . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
The purpose of this study was to determine the effect of aerobic exercise training ( Ex ) , a low fat diet ( LF , 19 % fat ) , or combined interventions ( LF Ex ) on lipoprotein cholesterol ( LDL , HDL , and VLDL ) and triglyceride ( TG ) concentrations in glucose intolerant subjects while their weight was maintained . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Fish or fish oil with a 40 % fat diet increased total cholesterol , HDL cholesterol , HDL 2 cholesterol , and LDL cholesterol , and reduced triglycerides . ^^^ The 30 % fat diet alone reduced cholesterol , LDL cholesterol , and HDL cholesterol , with triglycerides unchanged . ^^^ Fish with the 30 % fat diet reduced cholesterol , LDL cholesterol , and triglycerides and increased HDL 2 cholesterol . ^^^ Adverse effects of omega 3 fats on total and LDL cholesterol are reversed by a 30 % fat diet , whereas one daily fish meal substantially lowers triglycerides and reverses the fall in HDL cholesterol that is usual with a low fat diet . . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Plasma levels of Lp ( a ) and other parameters , including postheparin lipoprotein lipase ( LPL ) and hepatic lipase ( HL ) activities , triglycerides ( TG ) , total cholesterol ( TC ) , LDL cholesterol ( LDL C ) , and HDL cholesterol ( HDL C ) , as well as % body fat and muscle mass , and maximum aerobic capacity ( VO2max ) were measured to determine possible correlations with Lp ( a ) and to serve as convenient internal standards . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Evidence is provided demonstrating that women are able to increase their HDL cholesterol levels on a nutrition high in saturated and monounsaturated fat . ^^^ This could be explained by a concurrent dietary fat related increase in female sex hormone levels ( e . g . estradiol and estrone ) , hormones which are known to increase HDL cholesterol levels . . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Plasma TG levels were positively associated with both percent body fat ( r = 0 . 50 , p < 0 . 0001 ) and WHR ( r = 0 . 49 , p < 0 . 0001 ) , and negatively with VO2max ( r = 0 . 36 , p < 0 . 0001 ) , whereas plasma HDL C levels were negatively associated with percent body fat ( r = 0 . 50 , p < 0 . 0001 ) and WHR ( r = 0 . 54 , p < 0 . 0001 ) , and positively with VO2max ( r = 0 . 45 , p < 0 . 0001 ) . ^^^ Independent relationships between WHR and both plasma TG ( r = 0 . 30 , p < 0 . 001 ) and HDL C ( r = 0 . 34 , p < 0 . 0001 ) remained after correction for both percent body fat and VO2max . ^^^ Using analysis of covariance , the differences in TG and HDL C between groups remained after adjustment for percent body fat and VO2max . ^^^ These results suggest that in older men , an abdominal distribution of body fat , independent of both percent body fat and VO2max , is associated with elevated TG and low HDL levels , thus increasing the risk for CAD . . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
HDL cholesterol levels in amenorrheic subjects correlated positively with the percent of dietary calories from fat ( r = 0 . 42 , n = 23 , P = 0 . 045 ) but negatively with the percent from protein ( r = 0 . 49 , n = 23 , P = 0 . 017 ) . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Percent body fat , smoking habits , and Type A behavior score were negatively related to physical fitness level , and high density lipoprotein ( HDL ) cholesterol was positively related to physical fitness level . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Higher carbohydrate intake was associated with lower HDL cholesterol and apo A 1 concentrations , whereas higher total fat intake was associated with higher apo A 1 concentrations . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Both fat loads resulted in similar postprandial lipid responses : VLDL and high density lipoprotein ( HDL ) triglycerides reached maximum at 4 h after the meal . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
In the patients , cholesterol concentrations in the low ( LDL ) and high density ( HDL ) lipoprotein fractions were significantly lower than the respective levels in controls , but the ratio of cholesterol to triglyceride levels in both of these lipoprotein fractions decreased with the dietary fat intake . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Patients with chest pain had higher insulin responses to an intravenous glucose challenge , lower insulin sensitivity , lower high density lipoprotein ( HDL ) and subfraction 2 cholesterol , lower apolipoprotein AI , higher triglycerides , greater android fat and higher systolic blood pressure at rest compared with levels in healthy control subjects ( p < 0 . 05 ) . ^^^ Insulin sensitivity correlated positively with HDL ( p < 0 . 05 ) and subfraction 2 ( p < 0 . 001 ) cholesterol and negatively with triglycerides ( p < 0 . 01 ) , android fat proportion ( p < 0 . 01 ) and systolic blood pressure ( p < 0 . 05 ) , whereas insulin response showed converse correlations . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Fat modification without weight loss reduced HDL cholesterol by 11 . 1 % and the HDL / LDL ratio by 7 . 7 % , while weight loss per se led to increases in HDL cholesterol of 12 . 5 % and in the HDL / LDL ratio of 24 . 0 % . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
In a 1 year comparison of fat loss by dieting vs . fat loss by exercise without dieting , both methods were found to be effective in moderately overweight men , and both approaches raised plasma HDL cholesterol . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
For the evaluation of fat metabolism in 45 overhaul workers of a chemical plant producing pesticides , the serum concentration of total cholesterol and its LDL nd HDL fraction ( also HDL 2 and HDL 3 ) , apolipoprotein A and B , phospholipids and triglycerides were estimated . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Total body fat ( as determined by the tritiated water dilution method ) , plasma glucose , insulin , lipoproteins ( triglyceride , cholesterol and HDL and LDL cholesterol ) and free fatty acids ( FFA ) , and glucose disappearance rate ( KG ) and peripheral insulin stimulated glucose uptake ( M ) were obtained . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Selective breeding has produced families of baboons that accumulate large high density lipoproteins ( HDL 1 ) when challenged with a high cholesterol and high fat ( HCHF ) diet . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Thus FHC patients and controls had normal body weight and fat distribution , glucose tolerance , blood pressure , and serum triglyceride and HDL cholesterol concentrations , but were completely separated on plasma LDL cholesterol concentrations ( 6 . 05 + / 0 . 38 5 3 . 27 + / 0 . 15 mmol / L , P < . 0001 ) . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Substitution of complex carbohydrates for saturated fat in the diet showed consistent and significant decreases in total and LDL cholesterol , no decreases in HDL cholesterol , or elevation of total or VLDL TG . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Every three months food records , weight , waist hip ratio ( W : H ) , percent body fat , fasting plasma triglyceride , cholesterol ( C ) , high density lipoprotein cholesterol ( HDL C ) , HDL 2 C , and HDL 3 C ; apolipoprotein B and A 1 , and postheparin lipoprotein lipase ( LPL ) and hepatic triglyceride lipase activities were determined . ^^^ Changes in HDL C and / or HDL 2 C and LPL correlated directly with the changes in dietary fat and inversely with dietary carbohydrate . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
The effect of total parenteral nutrition ( TPN ) containing fat on plasma lipoproteins and apo A 1 rich HDL catabolism was studied in the rat . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Height , body weight , body fat , occupation and coronary heart disease risk factors including physical activity ( PA ) , fitness , blood pressure ( BP ) , serum cholesterol , HDL cholesterol , triglyceride ( TG ) and smoking habits were assessed . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Plasma triglyceride concentration was lower among high fat fish consumers than in other groups , but no differences between groups were observed for concentration of cholesterol , LDL cholesterol , and HDL cholesterol . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
In black women , high density lipoprotein cholesterol was the only measurement adversely affected by abdominal fat ; HDL cholesterol was significantly lower in the black UBO group ( 1 . 14 + / 0 . 05 mM ) compared with the black LBO group ( 1 . 37 + / 0 . 08 mM ) . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Dietary fat increases high density lipoprotein ( HDL ) levels both by increasing the transport rates and decreasing the fractional catabolic rates of HDL cholesterol ester and apolipoprotein ( Apo ) A 1 . ^^^ In humans , diets high in saturated fat and cholesterol raise HDL cholesterol ( HDL C ) levels . ^^^ The mice responded to increased dietary fat by increasing both HDL C and apo A 1 levels , with a greater increase in HDL C levels . ^^^ Turnover studies with doubly labeled HDL showed that dietary fat both increase the transport rate ( TR ) and decreased the fractional catabolic rate of HDL cholesterol ester ( CE ) and apo A 1 , with the largest effect on HDL CE TR . ^^^ The latter suggested that dietary fat increases reverse cholesterol transport through the HDL pathway , perhaps as an adaptation to the metabolic load of a high fat diet . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
A 60 % replacement of the coconut fat in the basal diet by pure oleic acid , respectively , by 0 . 6 % of eicosapentaenoic acid or eicosatrienoic acid significantly decreased the total cholesterol concentration in serum by 21 % ( HDL 28 % ; LDL 15 % ; VLDL 48 % ) , respectively , 19 % ( HDL 12 % ; LDL 42 % ; VLDL +69 % ) or 15 % ( HDL 11 % ; LDL 21 % ) and the total free cholesterol concentration by 22 % ( HDL 27 % ) , respectively , 41 % ( HDL 31 % ; LDL 66 % ) or 23 % ( HDL 21 % ; LDL 31 % ) . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Officers had less body fat , higher aerobic capacity , lower resting heart rates , lower resting diastolic blood pressure , higher HDL , and marginally lower triglycerides . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Lower concentrations of plasma triglycerides , HDL cholesterol , and apoA 1 for polyunsaturated fat fed animals were found only in the postweaning period ( 6 60 months of age ) . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
The fatty acid composition of HDL phospholipid was slightly reflected by the major dietary fat source . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
An increase in serum triglyceride and a decrease in serum HDL cholesterol levels was observed in both groups of rats fed normal chow plus high fat cheese . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Low fat and complex carbohydrate diet along with regular aerobic exercise may help reduce abdominal obesity , improve insulin sensitivity and HDL cholesterol levels . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Fat modified diets therefore may not improve the ratio of LDL to HDL cholesterol . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
The comparison of younger men to middle aged men with comparable levels of abdominal visceral fat and total body fat eliminated the age related differences in plasma triglyceride and in the ratio of plasma cholesterol to HDL cholesterol , whereas the difference in plasma apolipoprotein B levels , although still significant , was largely reduced . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
PAI 1 Ag and activity and TPA Ag were positively correlated with serum triglyceride levels , the abdominal to total body fat ratio ( as assessed by total body dual energy 10 ray absorptiometry ) , fasting blood glucose , and systolic BP and negatively with HDL cholesterol and sex hormone binding globulin . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Feeding the transgenic mice a high fat , high cholesterol diet maintained the mouse apoA 1 concentration at a normal level ( 69 + / 14 mg / dl in line 11 . 1 compared with 71 + / 6 mg / dl in nontransgenic controls ) and prevented the appearance of HDL deficiency . ^^^ Paradoxical HDL elevation by high fat diets has been observed in humans and is reproduced in human apoA 2 overexpressing transgenic mice but not in control mice . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Significant correlations were found between WHR and plasma cholesterol ( TC ) , plasma LDL cholesterol ( LDL c ) and LDL c to the plasma HDL cholesterol ratio ( LDL c / HDL c ) , independent of age , percent body fat , and VO 2 per lean body mass at blood lactate threshold ( LT ) . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Similarly , a direct relationship between dietary fat and HDL cholesterol was limited to this single subgroup of postmenopausal women . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
In obese girls , intraabdominal fat but not BMI or waist to hip ratio was highly correlated with basal insulin ( r = 0 . 55 , P < 0 . 04 ) , triacylglycerols ( r = 0 . 53 , P < 0 . 03 ) , and high density lipoprotein ( HDL ) cholesterol ( r = 0 . 54 , P < 0 . 04 ) . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
The CV of HDL cholesterol was 5 . 3 % during baseline , 4 . 2 % during the high fat diet , and 3 . 2 % during the low fat diet ( P = 0 . 4 , 0 . 19 , respectively ) . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Logistic regression analysis indicated that the prevalence of CHD among American Indians was significantly related to age , diabetes , hypertension , albuminuria , percentage of body fat , smoking , high concentrations of plasma insulin , and low concentrations of HDL cholesterol . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
With the above results the total serum cholesterol , serum triglyceride , HDL and LDL serum cholesterol and nutritional status ( body mass index , percentage of body fat and waist hip / ratio ) were compared . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
When maintained on a low fat diet , HDL isolated from both strain C57BL / 6J ( B 6 ) and C3H / HeJ ( C3H ) mice protect against LDL oxidation in a coculture model of the artery wall . ^^^ However , when maintained on an atherogenic diet high in fat and cholesterol , the HDL isolated from B 6 mice lose the capacity to protect , whereas HDL from C3H mice protect equally well . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Since insulin resistance is at least partially genetically determined , we hypothesized that genes influencing insulin resistance would have pleiotropic effects on a number of other traits , including triglyceride ( TG ) and HDL cholesterol levels , body mass index ( BMI ) and body fat distribution , and blood pressure levels . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
In the hypertriacylglycerolemic group the normal fall in HDL cholesterol after a fat meal was reduced by 87 % ( P = 0 . 02 , fat meal compared with fat and cholesterol meal ) . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
The apoE 2 group ( n = 58 ) carrying E2 / 2 and E3 / 2 phenotypes showed lower age , race and sex adjusted mean values of body mass index ( BMI : weight / height2 ) , percent body fat , fasting plasma insulin and LDL cholesterol , and a higher value of HDL cholesterol than the apoE 3 group ( n = 476 ) carrying the E3 / 3 phenotype ( P < 0 . 01 ) . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Old hens fed prilled fat had lower egg weight , increased egg production , lower plasma high density lipoprotein ( HDL ) cholesterol ( P < 0 . 08 ) , and reduced energy . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Subjects at the third tertile of FPI concentrations were the oldest and heaviest , with prevalent upper body fat distribution , and had enhanced fasting plasma triglyceride and potassium concentrations , lower fasting plasma high density lipoprotein ( HDL ) cholesterol concentration , and a greater number of VPCs versus subjects at the first and second tertiles . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Various blood samples were taken before the test , at hourly intervals up to 8 hours , and 24 hours after ingestion of the fat load for determination of HDL cholesterol , HDL TG , and HDL apolipoprotein ( apo ) A 1 concentrations . ^^^ A reduction in plasma HDL cholesterol concentrations was observed 3 to 8 hours after ingestion of the fat load , and the minimal postprandial HDL cholesterol concentration was , on average , 31 . 7 % ( P = . 04 ) lower than the fasting HDL cholesterol concentration . ^^^ HDL cholesterol had returned to the initial value 24 hours after the fat load . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
For this purpose , the first and fourth quartiles of apo A 1 and HDL cholesterol ( HDL C ) concentrations were compared in relation to body fat distribution , glucose tolerance , and plasma insulin and lipoprotein levels . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
The patients had increased relative weight ( P = 0 . 03 ) and body fat mass ( P < 0 . 001 ) , decreased serum high density lipoprotein ( HDL ) cholesterol ( P < 0 . 001 ) , and a reduced ratio of HDL to total cholesterol ( P = 0 . 01 ) . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
From a total of 12 pairs of young male identical twins who were overfed by an estimated 84 , 000 kcal over a period of 100 days , several pairs ( eight to 11 , depending on variables ) were remeasured for body weight , body composition with the underwater weighing technique , regional fat distribution from skinfolds , girths , computed tomography ( CT ) fat areas in the abdominal region , and fasting plasma glucose , insulin , total cholesterol , high density lipoprotein ( HDL ) cholesterol , and triglycerides 4 months and 5 years after completion of the overfeeding protocol . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
The regression equations predicting the SI the glucose and insulin AUCs , and the triglyceride and HDL cholesterol levels from regional adipose tissue measurements ( VAT , SCAT , or VAT / SCAT ) and from total body fat ( FM or percentage body fat ) had slopes that were not significantly different for black and white women . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
OBJECTIVE : This study investigated whether a low dose of fish oil had the ability to prevent the adverse effects associated with low fat dietary treatment , namely elevated plasma triacylglycerol ( TAG ) and reduced high density lipoprotein ( HDL ) cholesterol concentrations . ^^^ CONCLUSION : This study demonstrated that some of the deleterious effects of a low fat diet , reduced concentrations of the cardioprotective HDL 2 cholesterol fraction and increased fasting plasma TAG concentrations were prevented when a low dose of fish oil was provided with a low fat diet . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
In nonobese patients with primary hypercholesterolemia , pravastatin treatment in combination with an isocaloric , reduced fat diet leads to a marked reduction in LDL cholesterol and triglycerides levels and a normalization of the LDL : HDL ratio without affecting glucose tolerance or insulin sensitivity . . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
In a randomized crossover trial , a diet containing 300 g shrimp / d , which supplied 590 mg dietary cholesterol / d , significantly increased low density lipoprotein ( LDL ) cholesterol by 7 . 1 % ( P = 0 . 014 ) and high density lipoprotein ( HDL ) cholesterol by 12 . 1 % ( P = 0 . 0001 ) when compared with a baseline diet matched for fat content but containing only 107 mg cholesterol / d . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Logistic regression analysis indicated that prevalent CHD was significantly related to age , diabetes , hypertension , albuminuria , percent body fat , smoking , high concentrations of plasma insulin , and low concentrations of high density lipoprotein ( HDL ) cholesterol . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
When the data were analyzed on an individual basis , significant associations were observed between changes in body fat mass and changes in the low density lipoprotein ( LDL ) cholesterol / high density lipoprotein ( HDL ) cholesterol ratio ( r = . 62 , P = . 04 ) or triglyceride ( TG ) levels ( r = . 64 , P = . 03 ) . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Compared with those eating higher fat , subjects eating 16 % fat had lower HDL cholesterol ( 50 + / 3 vs 62 + / 3 mg . dl 1 , P < 0 . 0001 ) and Apolipoprotein A 1 ( 111 + / 6 5 . 134 + / 6 mg / dl , P < 0 . 0005 ) and a higher TC / HDL C ratio ( 4 . 05 + / 0 . 27 vs 3 . 42 + / 0 . 24 , P < 0 . 0005 ) . ^^^ Runners who increased fat intake to 42 % further raised HDL cholesterol ( 64 + / 6 to 69 + / 5 mg . dl 1 , P < 0 . 04 ) without adversely affecting other lipoproteins . ^^^ In conclusion , a 42 % fat diet maintained favorable CHD risk factors in female and male runners whereas a 16 % fat diet lowered Apo A 1 and HDL C and raised the TC / HDL C ratio . . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
RESULTS : Directly after termination of parenteral feeding , the serum levels of triglycerides were similar in all PN groups , while the levels of non high density lipoprotein ( HDL ) cholesterol and non HDL phospholipids were significantly increased in parallel with increased doses of fat . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
At baseline , obese patients were younger ( p < 0 . 0001 ) and had more systemic hypertension ( p < 0 . 01 ) , and diabetes mellitus ( p < 0 . 05 ) and higher percent body fat ( p < 0 . 0001 ) , total cholesterol ( p = 0 . 02 ) , triglycerides ( p < 0 . 0001 ) , fasting glucose ( p = 0 . 04 ) , and low density lipoprotein ( LDL ) high density lipoprotein ( HDL ) cholesterol ( p < 0 . 0001 ) , but had lower HDL cholesterol ( p < 0 . 01 ) and exercise capacity ( p = 0 . 07 ) than patients not classified as obese . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
The trans rich fat significantly elevated total cholesterol and LDL cholesterol relative to the 16 : 0 rich and 18 : 1 rich fats and uniquely depressed HDL cholesterol relative to all of the fats tested . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
On stepwise regression analysis , body mass index accounted for 52 % ( negatively ) of the variance in alpha 1 HDL and for 16 % and 33 % ( positively ) for the variances in alpha 3 and pre beta 1 HDL , respectively . alpha 1 and pre beta 3 HDL increased significantly after low fat , oleic acid rich , or alpha linolenic acid rich diets . ^^^ The profile of alpha HDL particles and also of pre beta HDL particles therefore shifted to smaller species in obese subjects , and this was influenced by dietary fat . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Oil level affected serum total cholesterol , triglycerides and HDL cholesterol , which were significantly greater in mice fed high fat diets . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Low fat , high carbohydrate intake can increase plasma triglyceride ( TG ) and decrease HDL C . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
A low HDL cholesterol level is frequently but not consistently associated with inefficient postprandial fat clearance . ^^^ We studied triglycerides , retinyl palmitate and squalene and apolipoprotein B 48 after a fat loading test in one subject heterozygous for a novel point mutation of apolipoprotein A 1 ( A IFIN , Leu 159 > Arg ) and low HDL cholesterol level without coronary artery disease , and in 16 healthy controls with the same apolipoprotein E phenotype , 3 / 3 , as the proband . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Serum HDL cholesterol values are associated with apoB containing lipoprotein metabolism and triglyceride body fat interrelation in young Japanese men . ^^^ Serum levels of total cholesterol , high density lipoprotein ( HDL ) cholesterol , triglyceride , apolipoprotein ( apo ) AI , ApoB , ApoE and body fat were measured in 226 fasting male Japanese college students aged 18 to 20 years . ^^^ These results suggest that serum levels of HDL cholesterol are associated with metabolism of apoB containing lipoproteins as well as triglyceride body fat interrelationship . . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
At both fat intakes , psyllium resulted in significant reductions in total , low density lipoprotein ( LDL ) , and high density lipoprotein ( HDL ) cholesterol compared with the wheat bran control . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Percent fat , computed tomography intra abdominal adipose tissue ( IAF ) , anthropometrics , Baecke activity questionnaire , and CVD risk ( blood pressure , cholesterol , HDL , HDL 2 , HDL 3 , IDL , LDL , VLDL , and triglycerides ) were evaluated in 137 men 30 71 yr old . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
We examined common polymorphisms in the genes encoding the LDL receptor , lipoprotein lipase , apoAI , apoB , apoAIV and cholesteryl ester transfer protein and related them to changes in LDL and HDL cholesterol after high fat / high cholesterol diets . 2 . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
MEASUREMENTS : ( 1 ) Anthropometry : waist circumference , waist to hip ratio , waist to height ratio , abdominal sagittal and transverse diameters and their ratio . ( 2 ) Dual energy 10 ray absorptiometry : the amount of total and regional abdominal fat . ( 3 ) Metabolic measurements : serum total , VLDL , LDL , HDL cholesterol , triglycerides , fasting and postglucose serum insulin and glucose . ^^^ As to dual energy 10 ray absorptiometry results , the region from the dome of diaphragm to the top of femur ( ' abdominal fat ' ) and the area between the first and the fourth lumbal vertebrae ( ' upper lumbal fat ' ) inversely related to HDL cholesterol and positively to triglycerides . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
RESEARCH DESIGN AND METHODS : In a controlled , 8 week intervention , 55 sedentary NIDDM subjects with serum triglycerides > 1 . 8 mmol / l and / or HDL cholesterol < 1 . 0 mmol / l were randomly assigned to a low fat diet ( 30 % daily energy intake ) with or without one fish meal daily ( 3 . 6 g omega 3 / day ) and further randomized to a moderate ( 55 65 % VO2max ) or light ( heart rate < 100 bpm ) exercise program . ^^^ CONCLUSIONS : A reduced fat diet incorporating one daily fish meal reduces serum triglycerides and increases HDL 2 cholesterol in dyslipidemic NIDDM patients . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
The differences in HDL cholesterol and apo A 1 levels between genotypes persisted during different diets suggesting that the possible benefit is independent of fat and cholesterol intake . . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Compared with the dairy fat diet , stearic acid and trans fatty acids decreased serum total cholesterol concentrations similarly ( by 13 % and 12 % , respectively , P < 0 . 001 ) but the trans fatty acid diet decreased HDL cholesterol ( 17 % ) and apolipoprotein ( apo ) A 1 ( 15 % ) significantly more than did the stearic acid diet ( 11 % and 12 % , respectively ) . ^^^ The trans fatty acid diet increased the ratio of LDL to HDL cholesterol ( 19 % ) and of apo B to apo A 1 ( 16 % ) more than did the dairy fat diet ( P < 0 . 001 ) but the stearic acid diet had no effect . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
A significant interaction between saturated fat intake and apoA 4 phenotype was found for HDL cholesterol ( P < . 0003 ) and LDL / HDL cholesterol ratio ( P < . 003 ) . ^^^ Increased saturated fat intake ( 13 . 6 % versus 8 . 6 % of calories ) was significantly associated with 6 % higher HDL cholesterol and no change ( 0 . 7 % ) in LDL / HDL cholesterol ratio in apoA 4 1 homozygotes and with 19 % lower HDL cholesterol and 37 % higher LDL / HDL cholesterol ratio among carriers of the apoA 4 2 allele . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
The substitution of monounsaturated fat for saturated fat lowers LDL and makes it less susceptible to oxidation without decreasing high density lipoprotein ( HDL ) cholesterol . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
The susceptibility of C57BL / 6 mice has been linked to decreased plasma HDL cholesterol in response to a diet containing fat , cholesterol , and cholic acid . ^^^ Feeding C57BL / 6 mice a diet consisting of fat and cholesterol , but no cholic acid , increased plasma high density lipoprotein ( HDL ) cholesterol . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Incubation of macrophages with bovine serum albumin or HDL reduced expression of CD 36 mRNA in a dose dependent manner . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
The males had both higher waist to hip ratio ( WHR ) , sagittal diameter , blood pressure , fat cell volume , plasma insulin , glucose , and triglyceride and lower HDL cholesterol levels than the females . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
The purpose of this study was to determine which of the fat distribution variables ( arm fat , leg fat , trunk fat , IAF , or SAF ) may have independent relations with cardiovascular ( CVD ) risk factors [ serum triacylglycerol , serum cholesterol , high density lipoprotein ( HDL ) cholesterol , HDL 2 cholesterol , HDL 3 cholesterol , low density lipoprotein ( LDL ) cholesterol , very low density lipoprotein ( VLDL ) cholesterol , VLDL 3 cholesterol , lipoprotein ( a ) , and systolic and diastolic blood pressure ] in women after adjusting for age , menopause status , and other fat distribution variables . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Blood samples were analyzed for serum concentration of total cholesterol ( TC ) , and high density lipoprotein ( HDL ) , blood pressure , body fat and maximal aerobic power ( VO2max ) were determined . ^^^ The ' univariate ' longitudinal analyses showed significantly positive relations : ( 1 ) between the intake of animal protein , saturated fat ( SFA ) , cholesterol ( Cho 1 ) and TC , and HDL ; ( 2 ) between total energy intake ( EN ) and systolic blood pressure , and VO2max . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
The relationship between changes in the measurements between 1 and 4 yr of follow up ( N = 34 ) revealed the following significant ( P < 0 . 05 ) correlations : 1 ) changes in VO2max with changes in percent body fat ( r = 0 . 289 ) and changes in plasma triglycerides ( r = 0 . 354 ) , 2 ) changes in LTPA with changes in percent body fat ( 0 . 361 ) , and 3 ) changes in percent body fat with changes in the total / high density lipoprotein ( HDL ) cholesterol ratio ( 0 . 358 ) , HDL cholesterol ( 0 . 212 ) , and triglycerides ( 0 . 289 ) . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
We conducted a meta analysis to determine the effect of consumption of psyllium enriched cereal products on blood total cholesterol ( TC ) , LDL cholesterol ( LDL C ) and HDL cholesterol ( HDL C ) levels and to estimate the magnitude of the effect among 404 adults with mild to moderate hypercholesterolemia ( TC of 5 . 17 7 . 8 mmol / L ) who consumed a low fat diet . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
OBJECTIVE : To study the impact of physical activity on glycemic control and plasma lipids [ HDL cholesterol ( HDL C ) , HDL C subfractions , triglycerides , lipoprotein ( a ) ] , blood pressure , weight , and abdominal fat and to determine the necessary short term adaptations in diabetes management during intensive endurance training in patients with IDDM . ^^^ CONCLUSIONS : This study shows that increasing physical activity is safe and does not result in more hypoglycemic episodes and that there is a linear dose response between increased physical activity and loss of abdominal fat and a decrease in blood pressure and lipid related cardiovascular risk factors , with a preferential increase in the HDL 3 C subfraction . . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Low fat , high carbohydrate diets lower plasma low density lipoprotein ( LDL ) but also lower high density lipoprotein ( HDL ) concentrations and raise plasma very low density lipoprotein . ^^^ Weight loss with low fat diets is modest and insufficient to offset the fall in HDL . ^^^ In contrast , diets low in saturated fat but high in unsaturated oils improve the ratio of HDL to LDL in plasma and thus reduce the predicted coronary risk . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
In the past 5 y a series of metabolic studies has provided unequivocal evidence that trans fatty acids increase plasma concentrations of low density lipoprotein cholesterol and reduce concentrations of high density lipoprotein ( HDL ) cholesterol relative to the parent natural fat . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Plasma lipid , lipoprotein , and high density lipoprotein ( HDL ) apolipoproteins and subfractions were measured and compared with weight , percent fat , glucose , and insulin level . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
The benefits of a low fat diet combined with aerobic exercise include a reduction in LDL and blood pressure , while maintaining HDL through the HDL 2 subfraction . . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
When mice were challenged with a high fat , high carbohydrate diet , strong correlations between LPL activity and HDL cholesterol were seen in both the presence ( r = 0 . 45 , P = 0 . 03 ) and absence ( r = 0 . 73 , P < 0 . 001 ) of CETP . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
In this study , we have shown a different response of low and high density lipoprotein ( LDL and HDL ) fractions to dietary saturated fat ( coconut oil ) rich in lauric and myristic acids . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
When the data were analyzed by tertiles , increasing visceral fat area was associated with higher plasma triglycerides , lower HDL cholesterol , and a smaller plasma glucose decrement during the SITT . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Thus , CD 36 has been reported to bind oxidized LDL ( OxLDL ) and acetylated LDL ( AcLDL ) , while SR BI also binds native LDL and HDL . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Likelihood ratio tests revealed the presence of significant ( P < . 05 ) cross trait resemblance between body fat ( BMI and SF 6 ) and all lipid traits except CH and also between fat distribution ( TER and TER sf ) and CH / HDL and CH HDL . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
OBJECTIVE : To examine the relationships between the distribution and composition of subfractions of very low density ( VLDL ) , low density ( LDL ) and high density ( HDL ) lipoproteins and central fat deposition as measured by the waist to hip ratio ( WHR ) . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
The nonfat and 15 g fat meals did not generate noticeable postprandial variations except for HDL phospholipids ( P < 0 . 05 ) . ^^^ At the same time , triacylglycerol rich lipoprotein triacylglycerols , esterified cholesterol , LDL free cholesterol , HDL triacylglycerols , phospholipids , and free cholesterol increased whereas LDL and HDL esterified cholesterol decreased when the amount of ingested fat increased . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Human TGRLP ( d < 1 . 006 kg / L ) , LDL ( d = 1 . 006 to 1 . 063 kg / L ) , and HDL ( d = 1 . 063 to 1 . 210 kg / L ) were separated from normal subjects both in fasting and 2 to 3 hours after the ingestion of a meal containing 100 g fat . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
To identify the preferential CE acceptor particles among postprandial TRL subfractions , we investigated the effects of a typical Western meal ( 1200 kcal , 14 % protein ; 38 % carbohydrate ; and 48 % fat , monounsaturated / polyunsaturated ratio 4 : 1 ) on the rates of postprandial CE transfer from HDL to apoB containing lipoproteins in normolipidemic subjects ( n=13 ) . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Review of the literature on effects of the menopause and of estradiol 17 beta provides evidence for the following changes occurring at or after the menopause : increased total cholesterol and triglycerides ; decreased high density lipoprotein ( HDL ) and HDL subfraction 2 ; increased low density lipoprotein , particularly in the small , dense subfraction ; increased lipoprotein ( a ) ; increased insulin resistance ; decreased insulin secretion ; decreased insulin elimination ; increased android fat distribution ; impaired vascular function ; increased factor 7 and fibrinogen , and reduced sex hormone binding globulin . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Genetic analysis revealed a substantial heritability for weight , body mass index , percentage of body fat , lipoprotein ( a ) , high density lipoprotein ( HDL ) and HDL 2 cholesterol , without significant differences between the two groups . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Arterial risk factors that can be routinely identified and monitored , and modified by application of management protocols , include high blood pressure , high serum total and LDL cholesterol , low serum HDL cholesterol and raised serum triglycerides , poor blood glucose control , smoking , high body mass index and body fat distribution . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Significantly higher HDL cholesterol values ; lower triceps , scapula , and iliac subcutaneous fat thickness ; and lower smoking rates were noted in all physically active groups compared with the sedentary group , whereas body mass index did not differ significantly . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
After a high fat challenge , total cholesterol levels increased drastically due to an increase in the non HDL cholesterol as confirmed by FPLC analysis . ^^^ Therefore , the adverse effect of low HDL on atherosclerosis in mice was only evident when LDL cholesterol was markedly elevated by high fat challenge . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
RESULTS : In men , the DHEAS was significantly correlated to age ( r = . 32 ) , TAM ( r = . 27 ) , percent fat ( r = . 30 ) , HDL cholesterol ( r = . 34 ) , TT ( r = . 30 ) , VO2max ( r = . 23 ) , and percent lean body mass ( % LBM ) ( r = . 33 ) . ^^^ In men , after partialling out age , DHEAS was significantly correlated to HDL , % fat , TAM , % LBM , and TT . ^^^ The men in the highest quartile of serum DHEAS levels were different from those in the lowest quartile in terms of age , TT , FT , % fat , TAM , % LBM , HDL , and low density lipoprotein ( LDL ) cholesterol level . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Obesity and , in particular abdominal obesity , seems to determine TG and HDL cholesterol levels : black males are less centrally obese than whites , while total adiposity and central distribution of fat is more predominant in black females compared with white females . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
The fifth quintile by estimated VO2max had significantly lower percentage body fat , higher athletic scores , higher fruit intake , lower total serum cholesterol , and lower ratios of total serum cholesterol to HDL cholesterol than members of the first quintile . ^^^ When the members of the first and fifth quintiles by percentage body fat were compared , the first quintile had significantly lower weight , lower body mass index , higher estimated VO2max , higher athletic scores , lower ratios of total serum cholesterol to HDL cholesterol , and higher fruit , carbohydrate , and fiber intakes . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Human CD 36 is a high affinity receptor for the native lipoproteins HDL , LDL , and VLDL . ^^^ By transient expression of human CD 36 in mammalian and insect cells , we demonstrate that CD 36 is a high affinity receptor for the native lipoproteins HDL , LDL , VLDL , and , as previously reported , for OxLDL and AcLDL . ^^^ Furthermore , at least for HDL , binding to CD 36 does not require the presence of apoE . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
RESULTS : Fasting plasma cholesterol , triglyceride , and high density lipoprotein ( HDL ) cholesterol levels ; HDL subfraction distribution ; dietary energy , fat , and protein content intake ; and height , weight , weight change , and energy expenditure were measured . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
We made a survey of the patients ' risk factors : total cholesterol , high density lipoprotein ( HDL ) cholesterol , triglycerides , glucose , blood pressure , body fat percentage , physical fitness , hereditary factors , smoking habits , and degree of stress . ^^^ In the epilepsy group , however , there was a trend toward higher levels of total cholesterol , higher levels of HDL cholesterol , lower levels of total cholesterol / HDL cholesterol ratio , increased body fat percentage , greater heredity and somewhat greater coronary risk score as compared with the healthy controls , but the differences did not reach statistical significance . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
We studied the effect of a single oral fat load , supplemented with retinyl palmitate ( RP ) , on high density lipoprotein ( HDL ) lipids in six normolipidemic men with coronary artery disease ( CAD ) and in six age and lipid matched controls . ^^^ Following the fat load , control subjects showed no change in HDL total cholesterol ( TC ) or HDL cholesteryl ester ( CE ) and showed an increase in HDL TG . ^^^ In control subjects an increase in HDL phospholipid ( PL ) was apparent between 0 and 8 h after the fat load . ^^^ The effects of the fat load on HDL free cholesterol ( FC ) were similar to the changes in HDL PL . ^^^ The data suggest that differences in the post prandial response to an oral fat load in normolipidemic CAD patients and control subjects are not confined to the clearance of TG rich lipoproteins , but also involve a difference in the uptake of chylomicron surface material by HDL . . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Although substitution of carbohydrates for fat lowers the blood level of low density lipoprotein ( LDL ) cholesterol , it also lowers the level of high density lipoprotein ( HDL ) cholesterol , thereby adversely influencing the risk profile for cardiovascular disease . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
The results indicated that the android pattern of fat distribution , independent of general obesity , was positively correlated with blood pressure , atherogenic indices , fasting and OGTT 2 h plasma glucose , glycosylated hemoglobin ( HbA1c ) , serum concentration of cholesterol , triglyceride , LDL cholesterol and negatively correlated with HDL cholesterol in both genders . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Studies that have used imaging techniques to assess the regional distribution of body fat have shown that an excess of visceral adipose tissue , that is , a high accumulation of fat in the abdominal cavity , was associated with a cluster of metabolic disturbances such as insulin resistance , hyperinsulinemia , glucose intolerance , hypertriglyceridemia , elevated apolipoprotein B ( apoB ) concentrations , small , dense low density lipoprotein ( LDL ) particles , as well as low HDL cholesterol levels . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
LDL particle size and LDL and HDL cholesterol changes with dietary fat and cholesterol in healthy subjects . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
The class B type 1 scavenger receptor , ( SR BI ) , is a member of the CD 36 superfamily of proteins and is a physiologically relevant , high affinity cell surface high density lipoprotein ( HDL ) receptor that mediates selective lipid uptake . ^^^ The abilities of SR BI and CD 36 , both of which are class B scavenger receptors , to bind HDL and mediate cellular uptake of HDL associated lipid when transiently expressed in COS cells were examined . ^^^ Although both mSR BI and human CD 36 ( hCD 36 ) could mediate the binding of HDL in a punctate pattern across the surfaces of cells , only mSR BI efficiently mediated the transfer of lipid to the cells . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
These results suggest that exercising before a fat meal may have a beneficial effect on the triglyceride response and HDL metabolism , which may blunt atherosclerotic process induced by the fat meal . . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
We examined the relation between carbohydrate intake and HDL cholesterol in hypercholesterolemic children consuming fat restricted diets . ^^^ HDL cholesterol was positively correlated with intake of total fat ( r = 0 . 44 , P < 0 . 001 ) and saturated fatty acids ( r = 0 . 43 , P < 0 . 001 ) and inversely correlated with intake of total carbohydrate ( r = 0 . 55 , P < 0 . 001 ) and simple carbohydrate ( r = 0 . 40 , P < 0 . 001 ) , but not with complex carbohydrate ( r = 0 . 02 ) . ^^^ In summary , higher dietary intake of simple carbohydrates was associated with lower HDL cholesterol concentrations in hypercholesterolemic children consuming reduced fat diets . . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
CONCLUSION : When the amount of fat is similar , post prandial responses of TG , apoE , apoB 48 , apoB 100 and HDL cholesterol were comparable after different FTTs . . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Thyroid stimulating hormone , free thyroxine ( FT 4 ) , total T 3 , total cholesterol , LDL cholesterol , high density lipoprotein ( HDL ) cholesterol , triacylglycerols and total fat mass ( determined by dual energy 10 ray absorptiometry scan ) were obtained at baseline and after 3 months treatment with hydrotherapy . 3 . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
CONCLUSIONS : Compared to treatment with pure LCTemulsions , treatment with MCT / LCT emulsions evoked weaker biochemical reactions in terms of lower activity of lipoprotein lipase in fat and heart together with higher serum and HDL triglyceride levels . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
RESULTS : Total caloric intake as well as total fat and carbohydrate increased significantly after smoking cessation in the controls , but there were no dietary changes in the exercise group . high density lipoprotein ( HDL ) C 2 increased ( 7 . 6 mg 10 dL ( 1 ) , P < 0 . 01 ) in the exercise group , whereas the increases in HDL and its subfractions did not attain statistical significance in the contact control group . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
LDL PPD was positively correlated with HDL cholesterol ( R=0 . 20 , P=0 . 002 ) and was negatively correlated with apoB ( R=0 . 34 , P < 0 . 001 ) , triglyceride ( R=0 . 32 , P < 0 . 001 ) . percent body fat ( R=0 . 26 , P < 0 . 001 ) , body mass index ( R=0 . 24 , P < 0 . 001 ) , fat mass ( R=0 . 23 , P=0 . 001 ) , total cholesterol ( R=0 . 20 , P=0 . 002 ) . ^^^ In multiple regression analysis , apoB , triglyceride , HDL cholesterol , apoAI and percent body fat explained 18 % of LDLPPD variability . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
There were significant ( P < 0 . 05 ) univariate correlations between fat distribution and log triglycerides ( r=0 . 27 ) , log HDL cholesterol ( r= 0 . 23 ) , systolic blood pressure ( r=0 . 26 ) , and left ventricular mass ( r=0 . 37 ) . ^^^ Multiple regression analysis showed that the significant independent correlates for triglycerides and HDL cholesterol were age and fat distribution ; for systolic blood pressure , height and fat distribution ; and for left ventricular mass , height , race , sex , and fat distribution . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
In men , energy expenditure in physical activity was significantly associated with HDL cholesterol levels , as well as total fat and monounsaturated fat . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
OBJECTIVE : To determine whether substituting carbohydrate for saturated fat has any adverse effects on serum high density lipoprotein ( HDL ) cholesterol and triglycerides in free living individuals . ^^^ CONCLUSIONS : Replacement of saturated fat with carbohydrate from grains , vegetables , legumes , and fruit reduces total and LDL cholesterol with only a minor effect on HDL cholesterol and triglyceride . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
In controlled trials , low fat , high carbohydrate diets decrease HDL concentrations . ^^^ This finding is supported by epidemiologic studies in which populations eating low fat , high carbohydrate diets were shown to have low HDL concentrations . ^^^ Weight losses with consumption of low fat diets could theoretically counter effects on HDL , but in published trials weight losses have been modest and insufficient to offset the decrease in HDL concentrations induced by carbohydrates . ^^^ Thus , replacement of saturated fat by carbohydrates adversely affects plasma HDL concentrations ; replacement of saturated fat by unsaturated fatty acids deserves consideration as an alternative . . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Metabolic and molecular studies of high and low LDL and HDL cholesterol responses to dietary lipids have suggested that different mechanisms regulate plasma LDL cholesterol on the chow and on the high cholesterol high fat ( HCHF ) diet . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
In the present study , this hypothesis was tested by comparing the selective uptake of HDL CE mediated by mouse SR BI ( mSR BI ) with that mediated by rat CD 36 ( rCD 36 ) , a closely related class B scavenger receptor . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
RESULTS : A central or abdominal distribution of body fat was related to adverse concentrations of triacylglycerol , LDL cholesterol , HDL cholesterol , and insulin ; these associations were independent of race , sex , age , weight , and height . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Taurine treatment lowered serum LDL + VLDL cholesterol by 44 % in mice fed a high fat diet , while it elevated serum HDL cholesterol by 25 % . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
There was an inverse correlation between SR BI expression and apoA 1 and HDL cholesterol levels in transgenic mice fed either mouse chow or a diet high in fat and cholesterol . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Positive associations were also observed in women between femoral fat cell weight and fasting plasma insulin , TG , and CHOL levels and the CHOL / HDL CHOL ratio ( . 29 < or = r < or = . 42 , P < . 05 ) . ^^^ However , only plasma TG concentrations and the CHOL / HDL CHOL ratio were positively correlated with femoral fat cell weight in men ( r = . 30 , P < . 05 ) . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Inhibition of the selective uptake of CE from HDL and native modified LDL by SR B ligands clearly suggests that CLA 1 and / or CD 36 are involved at least partially in this process in HepG 2 cells . . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Dietary restriction of saturated fat and cholesterol decreases HDL ApoA 1 secretion . ^^^ We examined the mechanisms responsible for the decrease in HDL cholesterol ( HDL C ) levels after the consumption of a diet low in total fat , saturated fat , and cholesterol . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
We investigated dietary effects on pleiotropic relationships among 3 HDL cholesterol ( C ) subfractions ( HDL 1 C , HDL 2 C , and HDL 3 C ; levels quantified by gradient gel electrophoresis ) for 942 pedigreed baboons ( Papio hamadryas ) who were fed a basal ( Chow ) diet and a high cholesterol , saturated fat ( HCSF ) challenge diet . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Also , a significantly ( P=0 . 03 ) greater decrease in apoA 1 content of postprandial HDL was recorded after the unused fat meal . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
A control for concomitant association with body fat mass and glucose intolerance performed by partial correlation analyses revealed that , with the exception of the plasma HDL 2 C levels in the apo E 3 homozygotes , most of the significant associations between VO2max ( mL 10 kg ( 1 ) 10 min ( 1 ) ) and plasma lipoprotein lipid levels were mediated by concomitant variation in body fatness and glucose tolerance . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
CD 36 and LIMPII analogous 1 ( CLA 1 ) , a human homolog of the rodent scavenger receptor B 1 ( SR B 1 ) , binds high density lipoprotein ( HDL ) and mediates the selective uptake of HDL cholesterol ester ( CE ) by cultured transfected cells . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Therefore , we investigated the effect of a 4 week intervention program of exercise ( 2 , 200 kcal / wk ) and diet ( 1 , 000 kcal / d : 50 % carbohydrate , 25 % protein , and 25 % fat ; polyunsaturated / saturated fat ratio , 1 . 0 ) on glycemic control and HDL and LDL subfractions in 34 obese patients with non insulin dependent diabetes ( age , 49 + / 9 years ; body mass index [ BMI ] , 33 . 1 + / 5 . 1 kg / m2 ) . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Visceral fat area was the strongest correlate of HDL C ( r = 0 . 75 ; P < 0 . 001 ) and the total / HDL C ratio ( r = 0 . 86 ; P < 0 . 001 ) . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Traditionally , a low fat high carbohydrate diet was used to prevent CHD because it effectively reduces plasma cholesterol concentrations , but this dietary regimen increases plasma TAG concentrations and reduces HDL cholesterol concentrations . ^^^ Thus , there is reason for concern that the adverse effects of low fat high carbohydrate diets on TAG and HDL may counteract or negate the beneficial effect of reducing LDL cholesterol concentrations . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
HDL was transiently reduced on the high carbohydrate diet at weeks 1 , 4 , and 8 , whereas higher fat consumption maintained these levels . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Mean HDL cholesterol was positively associated with high body fat percent . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Compared with the low fat control diet , the test diet decreased total cholesterol ( 6 . 2 % + / 1 . 2 % , P < . 001 ) , low density lipoprotein ( LDL ) cholesterol ( 6 . 7 % + / 1 . 7 % , P < . 001 ) , apolipoprotein B ( 8 . 2 % + / 1 . 2 % , P < . 001 ) , and the ratios of LDL to high density lipoprotein ( HDL ) cholesterol ( 6 . 3 % + / 2 . 0 % , P = . 004 ) and apolipoprotein B to A 1 ( 5 . 4 % + / 1 . 5 % , P = . 001 ) . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Cholesterol , HDL cholesterol , triglycerides , blood pressure , BMI , and body fat distribution were assessed . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
The scavenger receptor class B type 1 ( SR BI ) and its human homologue CLA 1 ( CD 36 and LIMPII Analogous 1 ) have recently been identified to bind HDL and mediate the selective uptake of HDL lipids . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Distribution of waist to hip ratio , other indices of body fat distribution and obesity and associations with HDL cholesterol in children and young adults aged 4 19 years : The Third National Health and Nutrition Examination Survey . ^^^ BACKGROUND : Little data has been published on the association of indices of body fat distribution and HDL cholesterol ( HDL ) , a risk factor for cardiovascular morbidity , in representative samples of total populations of children and adolescents including blacks and Hispanics . ^^^ CONCLUSION : Further research is needed on the association of WHR , other indices of body fat distribution and HDL measured in childhood with subsequent risk of atherosclerosis . . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
No significant differences between both groups under study were found in terms of anthropometric and biochemical parameters ( BMI , % body fat , glycemia , insulin , C peptide , intact proinsulin , total proinsulin cholesterol , HDL , triglycerides , LDL , homeostatic model of insulin secretion and resistance ) . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Specifically , we determined whether visceral fat was associated with fasting insulin , insulin sensitivity ( Si ) , serum triglyceride ( TG ) concentration , or serum HDL cholesterol ( HDL C ) concentration ; whether visceral fat or Si was independently related to lipids ; and whether ethnicity influenced the relationship between visceral fat and risk factors . ^^^ Nonetheless , ethnicity was not independently related to either TG or HDL C ( P = 0 . 075 and 0 . 619 , respectively , after adjusting for total and visceral fat and sex ) . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
One week after the first fat load , plasma non HDL cholesterol ( P < 0 . 02 ) , and triglycerides ( P = 0 . 05 ) were increased , whereas HDL cholesterol was decreased ( P < 0 . 02 ) . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Stearic acid had a HDL C lowering effect compared to milk fat , but did not affect LDL C significantly . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
When the women consuming the high fat diet had ethanol added to their diet , they had 6 % lower plasma cholesterol ( P = 0 . 003 ) , 11 % lower LDL cholesterol ( P = 0 . 001 ) and 3 % higher HDL cholesterol ( P = 0 . 06 ) than when they had an equal amount ( % energy ) of carbohydrate added to their diet . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
LDL cholesterol did not differ from previous values for 20 24 % fat diets in either group , whereas in the change group there were higher concentrations of triacylglycerol and apolipoprotein B ; greater mass of HDL , large LDL 1 , small LDL 3 and LDL 4 , and HDL 3 ; lower concentrations of HDL cholesterol , apolipoprotein A 1 ; and lower mass of large LDL 1 and HDL 2 . ^^^ CONCLUSIONS : There is no apparent lipoprotein benefit of reduction in dietary fat from 20 24 % to 10 % in men with large LDL particles : LDL cholesterol concentration was not reduced , and in a subset of subjects there was a shift to small LDL along with increased triacylglycerol and reduced HDL cholesterol concentrations . . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Measures included anthropometry , fasting glucose , insulin , HbA1c , total and HDL cholesterol , triglycerides , apolipoprotein B , LDL particle size , nonesterified fatty acids ( NEFA ) , sex hormone binding globulin , resting energy expenditure ( REE ) , total and central abdominal fat ( by dual energy 10 ray absorptiometry ) , resting BP , APWV ( by applanation tonometry ) , physical activity , well being , and sexual function . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
The results of a multiple regression analysis revealed that 47 % of the variance in GIR among all study subjects was predicted by AUC 1 , fat L 1 4 , diastolic blood pressure ( dBP ) , HDL , and triglyceride as independent variables . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
In a multiple regression , insulin sensitivity was determined by body fat content and HDL cholesterol level , while the size of the IIa fibers was not included in the model . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Resting supine systolic and diastolic blood pressures decreased significantly by 7 and 3 mm Hg , respectively , and plasma total cholesterol , LDL cholesterol , and HDL cholesterol concentrations all fell ( by 21 . 6 % , 25 . 7 % , and 18 . 0 % , respectively ; all P < 0 . 001 ) on the low fat compared with the high fat diet . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
CONCLUSIONS : Obese subjects ( even upper body obese subjects ) with increased visceral and total body fat , high plasma insulin and triglycerides , and low HDL cholesterol concentrations do not have elevated UAE . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
We investigated the mechanistic basis for this effect in the hamster and sought to determine whether reduced plasma HDL cholesterol concentrations resulting from a high polyunsaturated fat diet are associated with a decrease in reverse cholesterol transport . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Baseline variables were blood pressure , weight , BMI , fat areas by computed tomography , skinfold thicknesses , abdominal circumference , plasma insulin , C peptide , cholesterol , LDL cholesterol , HDL cholesterol , HDL 2 cholesterol , and HDL 3 cholesterol , triglycerides , apoproteins A 1 and B , and diagnosis of diabetes and hypertension . ^^^ Using univariate logistic regression analysis , significant risk factors were intra abdominal fat ( P = 0 . 0090 ) , fasting glucose ( P = 0 . 0002 ) , 2 h glucose ( P = 0 . 0008 ) , fasting HDL cholesterol ( P = 0 . 0086 ) , fasting HDL 2 cholesterol ( P = 0 . 030 ) , fasting HDL 3 cholesterol ( P = 0 . 018 ) , fasting triglycerides ( P = 0 . 013 ) , systolic ( P = 0 . 0007 ) and diastolic blood pressure ( P = 0 . 0002 ) , and presence of diabetes ( P = 0 . 0023 ) . ^^^ Multiple logistic regression models adjusted for BMI and age showed that intra abdominal fat accounted for the effects of HDL cholesterol or triglycerides . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Statistical adjustment for differences in intra abdominal adipose tissue accumulation or total body fat mass also eliminated the associations between SHBG levels and metabolic variables , with the exception of the association between SHBG and HDL cholesterol levels ( r = 0 . 52 , P < 0 . 005 ) . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
MEASUREMENTS : Energy intake by 7 day recall , resting energy expenditure ( REE ) by indirect calorimetry , body composition determined by bioelectrical impedance ; C index , an anthropometric index of abdominal fat distribution , and waist hip ratio ( WHR ) , blood glucose serum leptin concentrations , total cholesterol , high density lipoprotein ( HDL ) cholesterol , triglycerides , uric acid , and insulin concentrations HOMA IRI ( homeostastis model assessment of insulin resistance index ) . ^^^ The relationship of leptin with HOMA IRI was still evident after adjusting for sex but was lost when absolute fat mass was added to the model ; HDL cholesterol and triglycerides appeared to be variables independent of leptin concentrations even when both sex and fat mass were added to the model . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
A simple regression analysis showed that BMI , total body fat mass , subcutaneous fat area and visceral fat area were all associated with serum triglycerides and the atherogenic index , ( total cholesterol HDL cholesterol ) / HDL cholesterol . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Phospholipid flippase , low HDL levels , and intestinal fat absorption : a new look at the ABCs of enterohepatic lipid flux . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Aging is associated with decreased growth hormone ( GH ) secretion and plasma insulin like growth factor 1 ( IGF 1 ) levels , increased total and abdominal fat , total and low density lipoprotein ( LDL ) cholesterol , and triglycerides , and reduced high density lipoprotein ( HDL ) cholesterol . ^^^ Multivariate regression revealed log IAUPGH , but not DEXA total body fat , to be an independent determinant of total ( P < . 001 for women and P = . 01 for men ) and LDL ( P < . 007 and P = . 05 ) cholesterol in both sexes and of HDL cholesterol ( P < . 005 ) and triglycerides ( P < . 03 ) in women . ^^^ Log IAUPGH , but not DEXA abdominal fat , was related to total ( P < . 005 and P < . 03 ) and LDL ( P < . 03 and P = . 05 ) cholesterol in both genders and to HDL in women ( P < . 05 ) . ^^^ Thus , endogenous nocturnal GH secretion predicts total , LDL , and HDL cholesterol levels independently of total or abdominal fat , suggesting that it is an independent cardiometabolic risk factor in healthy elderly people . . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
HDL subpopulation patterns in response to reductions in dietary total and saturated fat intakes in healthy subjects . ^^^ OBJECTIVE : The objective was to investigate the effect of reductions in total and saturated fat intakes on HDL subpopulations . ^^^ RESULTS : HDL ( 2 ) cholesterol concentrations , by differential precipitation , decreased ( P < 0 . 001 ) in a stepwise fashion after the reduction of total and saturated fat : 0 . 58 + / 0 . 21 , 0 . 53 + / 0 . 19 , and 0 . 48 + / 0 . 18 mmol / L with the AAD , Step 1 , and low fat diets , respectively . ^^^ HDL ( 3 ) cholesterol decreased ( P < 0 . 01 ) less : 0 . 76 + / 0 . 13 , 0 . 73 + / 0 . 12 , and 0 . 72 + / 0 . 11 mmol / L with the AAD , Step 1 , and low fat diets , respectively . ^^^ As measured by nondenaturing gradient gel electrophoresis , the larger size HDL ( 2b ) subpopulation decreased with the reduction in dietary fat , and a corresponding relative increase was seen for the smaller sized HDL ( 3a , 3b ) , and ( 3c ) subpopulations ( P < 0 . 01 ) . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Furthermore , modified milk fat maintained initial HDL ( 2 ) cholesterol concentrations , but margarine reduced this variable significantly ( P < 0 . 05 ) . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Monounsaturated fat , percentage body fat , and alcohol intake accounted for approximately 26 % of variance in HDL cholesterol . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
On both regular chow and high fat , high cholesterol diets , expression of CETP in LCAT Tg mice reduced total cholesterol ( 39 % and 13 % , respectively ; p < 0 . 05 ) , reflecting a decrease in HDL cholesterol levels . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
For this reason , exercise may be a means of reducing the hypertriglyceridaemic and HDL lowering effects of low fat ( high carbohydrate ) diets . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
The EURODIAB IDDM Complications Study , a cross sectional , clinic based study examined the fat and cholesterol intakes of European individuals with type 1 diabetes for possible relations to serum lipid levels ( total cholesterol , HDL and LDL cholesterol , fasting triglycerides ) and to the prevalence of cardiovascular disease ( past history or electrocardiogram abnormalities ) . ^^^ For levels of HDL cholesterol and triglycerides no independent associations were observed with fat or cholesterol intake . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Relationship with lipoprotein lipase , HDL , LDL , body fat , and insulin resistance . ^^^ As HDL ( 2 ) can be decreased by hepatic lipase and hepatic lipase is increased in obesity with increasing intra abdominal fat , the participants were divided into sub groups of non obese ( n = 35 ) and obese ( n = 15 ) individuals and the correlation of PLTP with HDL ( 2 ) cholesterol was re examined . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
For example , long term CR reduced body fat and serum triglycerides , and increased a subfraction of HDL cholesterol associated with decreased cardiovascular disease risk . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Diet affected the time course of changes in HDL cholesterol with both high fat diets , resulting in smaller reductions in HDL cholesterol at weeks 1 ( P = 0 . 0004 ) and 4 ( P = 0 . 02 ) ; however , these differences were no longer apparent by 12 wk . ^^^ Changes in HDL cholesterol between diets appear dependent on both the fat content of the diet and the duration of energy restriction . . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Differential response to low fat diet between low and normal HDL cholesterol subjects . ^^^ A low fat diet decreases both low density ( LDL ) and high density lipoproteins ( HDL ) . ^^^ We hypothesized that as subjects with low HDL C already have low HDL concentrations , the major decrease of HDL C will occur in subjects with normal HDL C when a low fat diet is consumed . ^^^ As a result of a low fat diet , low HDL C individuals slightly decreased their HDL C , but substantially decreased their LDL C resulting in a significant improvement in the LDL C / HDL C ratio . ^^^ We also observed significant differences in response to low fat diets in HDL C and alpha ( 1 ) concentrations between low and normal HDL C subjects . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Results indicated long term effects of the intervention on nutrition knowledge and fat avoidance , yet only short term effects on total cholesterol : HDL ratio and systolic blood pressure . . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Significant independent predictors of CVD in those with diabetes included age , albuminuria , LDL cholesterol , HDL cholesterol ( inverse ) , fibrinogen , and percent body fat ( inverse ) . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Decreasing dietary fat saturation lowers HDL cholesterol and increases hepatic HDL binding in hamsters . ^^^ In order to study the mechanism by which increasing unsaturation of dietary fat lowers HDL cholesterol levels , we studied various measures of HDL metabolism in hamsters fed with fats with different degrees of saturation . ^^^ Increasing saturation of dietary fat resulted in increasing concentrations of total plasma cholesterol ( 4 . 29 ( SD 0 . 51 ) , 5 . 30 ( SD 0 . 67 ) and 5 . 58 ( SD 0 . 76 ) mmol / l respectively , n 12 ) and HDL cholesterol ( 3 . 31 ( SD 0 . 50 ) , 3 . 91 ( SD 0 . 12 ) and 3 . 97 ( SD 0 . 43 ) mmol / l ) and these concentrations were significantly higher ( P < 0 . 05 ) in the palm oil and olive oil fed hamsters compared with the maize oil group . ^^^ The affinity of HDL 3 for the binding sites was not affected by the type of dietary fat . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Do stroke prevention patients with increased blood fat protein compounds ( total cholesterol , HDL and LDL cholesterol and triglyceride ) have a different method of coping than patients with normal blood fat . 1159 stroke prevention patients participated in the following stroke risk investigations at this hospital : biographical and risk factor orientated anamnesis , a neurological status investigation , a laboratory investigation , a sonographic investigation and a psychological investigation . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Thus , in healthy premenopausal women , a low fat vegetarian diet led to rapid and sizable reductions in serum total , LDL , and HDL cholesterol concentrations . . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
An inverse correlation ( r = . 241 ) was observed between the increase in HDL cholesterol and change in body fat only in men , and the increase in HDL cholesterol was unrelated to the change in maximal oxygen uptake ( VO2max ) . . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Impaired HDL response to fat in men with coronary artery disease . ^^^ We speculated that individuals with a normal total cholesterol and coronary artery disease have an impaired HDL response to dietary fat . ^^^ The high fat supplement increased HDL cholesterol from 0 . 79 to 0 . 89 mmol / l in the men with coronary artery disease while HDL increased from 0 . 88 to 1 . 05 mmol / l in the control group ( P < 0 . 05 for group difference ) . ^^^ Thus men with premature coronary artery disease and a low HDL cholesterol appear to have an impaired elevation of HDL cholesterol in response to dietary fat , and insulin resistance may underlie this response . . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
SR BI is found in the liver , where its expression is regulated by estrogen , dietary cholesterol and fat , and controls murine plasma HDL cholesterol levels and bile cholesterol secretion . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
For girls , systolic blood pressure was positively related to vitamin C intake ( P = 0 . 042 ) ; HDL cholesterol inversely to carbohydrate intake ( P = 0 . 014 ) , fat intake ( P = 0 . 031 ) , cholesterol intake ( P = 0 . 042 ) and smoking ( P = 0 . 035 ) and positively to energy intake ( P = 0 . 035 ) . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
No significant differences between the high fat diet groups were evident with respect to total cholesterol , LDL , HDL or triglyceride levels . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Significantly more remnant [ 3H ] cholesterol was secreted into the perfusate HDL by livers from rats fed on the olive oil , fish oil and butter fat diets when compared with those from rats fed on the low fat diet or the maize oil diet . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
In contrast , dietary hydrogenated fat / trans fatty acids have been reported have to have little effect or decrease HDL cholesterol levels , the later observation restricted to relatively high intakes of trans fatty acids . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Exercise induced changes in plasma HDL cholesterol were more related to changes in body composition and / or body fat distribution , rather than changes in peak aerobic capacity . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Dietary CA reduced plasma HDL levels by 35 % in NTg and 250 % in apoAI Tg mice , independent of the fat or cholesterol content of the diet . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
A multiple regression model containing gender , subcutaneous fat , fasting glucose , triglycerides , and high density lipoprotein ( HDL ) cholesterol explained 81 % of the variance in leptin levels . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Northern and Western blot analyses revealed the expression of CLA 1 ( CD 36 and LIMPII analogous 1 ) , the human homologue of the rodent HDL receptor SR BI . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
In the present study , we compared the expression and regulation patterns of LDL receptor and CLA 1 ( CD 36 and LIMPII Analogous 1 , an HDL receptor ) genes in adult human adrenocortical tissues to shed more light on the relative contribution of LDL and HDL in human adrenal steroidogenesis . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
BACKGROUND : Low fat diets can increase plasma triacylglycerol and reduce HDL cholesterol . ^^^ HDL cholesterol decreased during both low fat diets . . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
It was undertaken with the aim of investigating obesity indices ( i . e . body mass index , skin fold thickness , waist hip ratio and % fat in the body ) ; lipid profile ( including serum total cholesterol , triglyceride , VLDL , LDL and HDL cholesterol ) levels and platelet adhesiveness in both the groups . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Diets low in saturated fat and cholesterol , which lower HDL levels , do so by decreasing the secretion of apolipoprotein A 1 , with apolipoprotein A 2 kinetics unaffected . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
The electrophoretic mobilities of LDL , VLDL and HDL were increased when compared with the controls , and absorbance at 234 nm and TBARS of LDL , VLDL and HDL in the HTG group and in the high fat diet rabbits were significantly higher than those of the controls ( p < 0 . 01 ) . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
RESULTS : Positive family history of diabetes or impaired fasting glucose and type 2 diabetes in young adults of both races were significantly associated with adverse profiles of measures of obesity and abdominal fat ( body mass index , triceps and subscapular skinfolds , waist circumference , and abdominal height ) , systolic and diastolic blood pressures , serum total cholesterol , triglycerides , VLDL cholesterol , and HDL cholesterol , and indicators of glucose homeostasis ( plasma glucose and insulin and insulin resistance index ) . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
High heritability estimates were also observed for various measures of body size and body fat , left ventricular size , cardiac index , stroke volume , total peripheral resistance , and serum concentrations of LDL and HDL cholesterol and leptin . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
We studied the effects of exercise on high density lipoprotein ( HDL ) cholesteryl ester ( CE ) metabolism in 6 male and 6 female miniature pigs fed a commercial swine diet supplemented with cholesterol and fat . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
The subjective perception of fat wasting and / or accumulation in different sites of the body , which was possible to evaluate in 235 patients on HAART and 73 treatment naive patients , the levels of plasma triglycerides ( TG ) , cholesterol , LDL and high density lipoproteins ( HDL ) cholesterol , LDL / HDL ratio and Lp ( a ) were measured . ^^^ The Lp ( a ) levels correlated to the levels of LDL cholesterol , but not to total cholesterol , HDL cholesterol or TG , and did not differ between patients with and without subjective perception of abnormal fat distribution . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
CONCLUSIONS : Reduction in the intake of total fat and saturated fatty acids reduced serum LDL cholesterol and HDL 2 cholesterol concentrations irrespective of the relative proportions of MUFA and PUFA in the diets . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Alcohol consumption ranging from 0 . 1 to > 28 units week ( 1 ) was directly correlated with intakes of B vitamins , total energy and fat , with blood concentrations ( independent of intake ) of lycopene , high density lipoprotein ( HDL ) cholesterol , plasma pyridoxal phosphate and retinol , and with blood pressure and grip strength . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
However , compared with abdominally obese white individuals , abdominally obese black individuals have been characterized by higher plasma HDL cholesterol levels , suggesting that the impact of abdominal fat accumulation on the lipoprotein lipid profile may differ among ethnic groups . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
After mice consumed an atherogenic diet for 1 or 3 days , switching the mice to a low fat chow diet for 3 days resulted in a return to baseline levels of lipid hydroperoxides but only a small return toward baseline for HDL cholesterol , with no significant increase in apoA 1 mass or PON activity and mass . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
BACKGROUND : Low fat diets increase plasma triacylglycerol and decrease HDL cholesterol concentrations , thereby potentially adversely affecting cardiovascular disease ( CVD ) risk . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
These data suggest that the modulation of serum PON 1 activity by dietary fat may be mediated via the effect of the specific fatty acids on the synthesis and secretion of VHDL , the subfraction of HDL that transports the majority of PON 1 in the blood . . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Regular exercise decreased BMI , percentage body fat , HbA1c , serum TNF alpha , TNF RI and TNF RII and increased HDL cholesterol levels . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
The liver weight , fat and TG in the liver and serum concentrations of TG , NEFA , high density lipoprotein ( HDL ) and AST increased significantly ( P < 0 . 05 ) , while the level of very low density lipoprotein ( VLDL ) decreased ( P < 0 . 05 ) at the end of the withdrawal period . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
These data indicate that intakes of fat below about 25 en % and carbohydrate intake above approximately 60 en % yield no further LDL C lowering in HC and CHL male subjects and can be counterproductive to triglyceride , HDL C , and apo B levels . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
The subsequent low fat diet increased triglycerides ( +63 % ) , VLDL cholesterol ( +19 % ) , apoC 3 ( +23 % ) , apoC 3 LpB ( +44 % ) apoC 3 nonLpB ( +17 % ) , apoE ( +29 % ) and nonHDL E ( +43 % ) , and decreased HDL cholesterol ( 12 % ) , LPL ( 3 % ) , and LCAT ( 3 % ) . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
CONCLUSION : Black obese women demonstrate a higher degree of insulin resistance , despite less visceral fat and a higher HDL : total cholesterol ratio . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
To examine the genetic bases of these differences , we studied HDL lipid levels in an intercross between strain CAST and the common laboratory strain B 6 on a low fat , chow diet as well as a high fat , atherogenic diet . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
METHODS : The prevalence of high blood pressure , obesity , total cholesterol , high density lipoprotein ( HDL ) cholesterol , low density lipoprotein ( LDL ) cholesterol , sedentarism , family history of premature CHD , saturated fat intake , diabetes mellitus , and cigarette smoking was determined in 328 adolescents , ages 12 18 years ( 167 males , 161 females ) , randomly selected from San Jos ' s urban and rural high schools . ^^^ CONCLUSIONS : The prevalence of CHD risk factors among Costa Rican adolescents is high ; particularly of saturated fat intake , sedentarism and low HDL C levels . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Higher saturated fat intake was associated with higher VLDL cholesterol ( +29 % ) and lower HDL cholesterol ( 22 % ) in APOE 2 carriers , while the opposite association was observed in APOE 4 carriers ( 31 % for VLDL cholesterol and +10 % for HDL cholesterol ) . ^^^ These data suggest that the APOE 2 allele could modulate the effect of habitual saturated fat on VLDL cholesterol and HDL cholesterol in a population with an average habitual total fat intake of less than 30 % . . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
In the present study , the effects of IFNgamma on macrophage binding and uptake of fluorochrome labeled high density lipoprotein ( HDL ) were investigated by flow cytometry and by measuring the amount of the type B scavenger receptors CD 36 and scavenger receptor type B ( SR BI ) by Northern blot analysis . ^^^ Furthermore , 15d PGJ 2 increased the expression of SR BI and CD 36 message and SR BI protein which was reflected in an increase in HDL binding and uptake . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
CONCLUSION : Reductions in both dietary fat and energy may modify LDL cholesterol by lowering cholesterol biosynthesis ; however , the increase in HDL cholesterol and the suppression of triacylglycerol concentrations and LDL : HDL suggests that favorable plasma lipid profiles were also achieved through energy restriction alone . . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Although the hyperTG low HDL cholesterol dyslipidemia has been associated with an impaired clearance of dietary fat , the contribution of the small , dense LDL phenotype as an independent predictor of postprandial triglyceride ( TG ) clearance remains uncertain . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
CONCLUSIONS : NFG patients who had IGT or DGT had more intra abdominal fat and total adiposity ; higher insulin , C peptide , and triglyceride levels ; lower HDL cholesterol levels ; and higher BPs than those with NGT . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
CD 36 , a member of the type B scavenger receptor family , will bind a variety of nonlipoprotein and lipoprotein ligands including high density lipoprotein ( HDL ) . ^^^ The decrease in HDL binding was consistent with a significant reduction in CD 36 message levels . ^^^ A similar reduction in HDL binding and CD 36 message was also observed with the immunosuppressive glucocorticoid dexamethasone . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Troglitazone inhibits atherosclerosis in apolipoprotein E knockout mice : pleiotropic effects on CD 36 expression and HDL . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
The unadjusted correlation coefficients between the body fat measures , R ( 2 ) , were largest for fasting insulin and triglyceride and smaller for high density lipoprotein ( HDL ) cholesterol and blood pressure . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Relative to saturated fatty acids , trans fatty acids / hydrogenated fat enriched diets have been reported to increase low density lipoprotein ( LDL ) cholesterol levels and either decrease or have no effect on high density lipoprotein ( HDL ) cholesterol levels . ^^^ To better understand the effect of trans fatty acids / hydrogenated fat on HDL cholesterol levels and metabolism , 36 subjects ( female , n = 18 ; male , n = 18 ) were provided with each of three diets containing , as the major sources of fat , vegetable oil based semiliquid margarine , traditional stick margarine , or butter for 35 day periods . ^^^ There was virtually no effect of dietary fat on HDL 3 cholesterol levels . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
In contrast , CD 36 , a closely related class B scavenger receptor , has none of these activities despite binding HDL with high affinity . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
The reduction of dietary saturated fat with partial replacement of unsaturated fat brings about changes in total cholesterol , HDL and LDL cholesterol that are associated with a lower cardiovascular risk . . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Although there were relatively weak associations between dietary factors and both HDL subclasses ( r = 0 . 01 0 . 26 ) in men and women according to bivariate analyses , multiple regression models showed that total fat , saturated fat , and cholesterol intakes were significantly correlated with HDL cholesterol and both Lp A 1 and Lp A 1 : A 2 in men , but not in women . ^^^ CONCLUSION : Our data suggest that body adiposity and dietary fat consumption affect 2 major HDL subclasses differently depending on subject sex and menopausal status . . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Insulin sensitivity was inversely correlated with increases in blood pressure , triglycerides , subcutaneous fat , the percentage of total body fat , and Tanner stage , but it was not correlated with LDL and HDL . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
We determined total testosterone ( T ) , sex hormone binding globulin ( SHBG ) , free androgen index ( FAI ) , and estradiol ( E 2 ) and studied their relationship to body fat mass ( BF ) , blood pressure ( BP ) , aortic compliance , left ventricular mass ( LVM ) , and plasma lipids ( total cholesterol , high density lipoprotein [ HDL ] , low density lipoprotein [ LDL ] , very low density lipoprotein [ VLDL ] , and triglycerides ) . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
CD 36 does not play a direct role in HDL or LDL metabolism . ^^^ CD 36 and scavenger receptor class B , type 1 ( SR BI ) are both class B scavenger receptors that recognize a broad variety of ligands , including oxidized low density lipoprotein ( oxLDL ) , HDL , anionic phospholipids , and apoptotic cells . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
The associations with alcohol intake remained statistically significant and unaltered after adjustment for established IHD risk factors : HDL cholesterol , body mass index , systolic blood pressure , family history , education , physical activity and risk factors significantly related with IHD : fruit and vegetables consumption , type of fat used in cooking , bread consumption . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
METHODS : We measured total % body fat and body fat distribution ( reflected as centrality index ) by dual energy 10 ray absorptiometry , and plasma glucose , glycosylated haemoglobin , blood pressure , total cholesterol , triglyceride , high density lipoprotein ( HDL ) cholesterol and atherogenic index ( total cholesterol / HDL cholesterol ) . ^^^ After adjustment for age and total % body fat , men still had higher diastolic blood pressure , triglyceride levels and atherogenic indices , but lower HDL cholesterol levels than women . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Total cholesterol was reduced by 20 mg / dl ( 0 . 52 mmol / L ) , triglycerides by a mean of 40 mg / dl ( 0 . 45 mmol / L ) , and HDL cholesterol was increased by 5 mg / dl ( 0 . 13 mmol / L ) by restriction of fat intake or restriction of the intake of saturated fat and dietary cholesterol . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Dietary vitamin E and % energy from fat had positive effects , whereas plasma plasminogen activator inhibitor 1 , fibrinogen , body weight and serum ferritin had negative effects on HDL and total to HDL cholesterol . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Even though we do not yet dispose of sensitive enough methods to study the evolution of fat in coronary arteries , the high resolution images obtained in carotid or aortic plaques by magnetic resonance allow us to visualize the effect produced by statin therapy or by other protective maneuvers such as the reduction of LDL levels or the increase of HDL levels . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
The ponies fed the high fat diet had higher plasma HDL CE concentrations ( 1 . 08+ / 0 . 15 vs . 0 . 84+ / 0 . 11 mmol / l , mean+ / S . ^^^ The transport rates of HDL CE were not significantly different between ponies fed high fat ( 0 . 029+ / 0 . 008 mmol HDL CE / h per l plasma ) and those fed low fat diets ( 0 . 024+ / 0 . 004 ) . ^^^ HDL CE were transferred to low density lipoproteins ( LDL ) and we calculated that the percentage of LDL CE derived from HDL was 0 . 69+ / 0 . 13 in the ponies fed the low fat diet and 0 . 53+ / 0 . 05 in the ponies fed the high fat diet ( P < 0 . 05 ) . ^^^ The results of these in vivo studies suggest that in ponies , similarly as reported in rats and pigs , HDL CE can be transferred to LDL despite the absence of plasma CETP activity , and that the magnitude of this transfer is related to the levels of HDL CE as induced by the amount of fat in the diet . . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Dietary n 3 polyunsaturated fat increases the fractional catabolic rate of medium sized HDL particles in African green monkeys . ^^^ The purpose of the present study was to determine whether the reduction in concentration of medium HDL in African green monkeys consuming n 3 polyunsaturated versus saturated fat diets resulted from decreased in vivo production or increased catabolism . ^^^ We found a significant reduction of apoA 1 concentration in medium HDL in the animals fed n 3 polyunsaturated fat ( 31 . 2 + / 0 . 7 mg / dl ) compared with animals fed saturated fat ( 85 . 4 + / 11 . 9 mg / dl ; P = 0 . 002 ) . ^^^ The production rates of apoA 1 in small , medium , and large HDL were similar in both diet groups ; however , there was a significant increase in the fractional catabolic rate of apoA 1 in medium HDL in the animals fed n 3 polyunsaturated fat ( 2 . 188 + / 0 . 501 pools / day ) compared with animals fed saturated fat ( 0 . 714 + / 0 . 191 pools / day ; P = 0 . 02 ) . ^^^ We conclude that n 3 polyunsaturated fat reduces HDL cholesterol concentration by increasing the fractional catabolic rate of medium sized HDL particles in African green monkeys . . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
BACKGROUND : The aim of this study is to describe trends in plasma total and high density lipoprotein ( HDL ) cholesterol in The Netherlands between 1993 and 1997 and to examine whether these trends in cholesterol could be explained by changes in body mass index , smoking , alcohol intake , use of cholesterol lowering medication , intake of saturated fat , trans fatty acids and dietary cholesterol . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Changes in leg press strength , leg power , thigh and quadriceps muscle volumes , hemoglobin , and IGF 1 were positively correlated with testosterone concentrations , whereas changes in fat mass and plasma high density lipoprotein ( HDL ) cholesterol were negatively correlated . ^^^ We conclude that changes in circulating testosterone concentrations , induced by GnRH agonist and testosterone administration , are associated with testosterone dose and concentration dependent changes in fat free mass , muscle size , strength and power , fat mass , hemoglobin , HDL cholesterol , and IGF 1 levels , in conformity with a single linear dose response relationship . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
RESULTS : Among parameters related to insulin resistance , there were no differences in body mass index ( BMI ) , HDL cholesterol , total cholesterol , triglycerides , insulin and insulin resistance index ( HOMA IR ) , or blood pressure between 91 normal subjects ( 45 male and 46 female ) randomly selected from the 780 Pro 90 homozygotes and the 51 ( 29 male and 22 females ) CD 36 deficient subjects ( Ser 90 homozygote and Pro90Ser heterozygote ) . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
This appears to be driven by increased hepatic expression of enzymes of fat catabolism ( carnitine palmitoyltransferase 1 , acyl CoA oxidase , and uncoupling protein 2 ) and their coordinating transcription factor , peroxisome proliferator activated receptor alpha ( PPARalpha ) . 11beta HSD 1 ( / ) mice also have increased HDL cholesterol , with elevated liver mRNA and serum levels of apolipoprotein AI . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
The serum lipoprotein high density lipoprotein ( HDL ) , which is a ligand of scavenger receptors such as scavenger receptor class B type 1 ( SR BI ) and cluster determinant 36 ( CD 36 ) , can act as a donor particle for intestinal lipid uptake into the brush border membrane ( BBM ) . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
The association of CAG repeat with high density lipoprotein ( HDL ) cholesterol was independent of body fat content and serum levels of free T , which both had significant negative correlations with HDL cholesterol . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Eight major CHD factors were identified and criteria used for classifying them as high risk were as follows : high blood pressure ( SBP : over 160 mmHg or DBP : over 95 mmHg ) ; total blood cholesterol ( over 6 . 2 mmol / L ) or high density lipoprotein ( HDL ) under 0 . 9 mmol / L ; cigarette smoking ; overweight ( BMI over 27 . 5 , or percent body fat over 25 for men and 30 for women ) ; exercise habit ( no exercise or exercise less than once per week ) ; alcohol consumption ( over 6 drinks or 90 ml ethanol per week ) ; diabetes mellitus ; and family history ( one or both parents died of CHD before the age of 60 years ) . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Dietary fat saturation affects apolipoprotein AII levels and HDL composition in postmenopausal women . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
No significant differences in HDL C response were observed across quartiles by sex , race , age , or increase in VO ( 2 ) max with training ; however , weak positive associations were observed with age adjusted education level and with reduction in abdominal fat and increase in VO ( 2 ) max at the ventilatory threshold following training . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
The improvements of LDL , HDL , total cholesterol , apolipoprotein B concentrations , and LDL / HDL cholesterol ratio during the daily consumption of a phytosterol ester enriched margarine were most marked in those subjects with a high dietary intake of cholesterol , energy , total fat , and saturated fatty acids and with high baseline cholesterol absorption . . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
RESULTS : LBW was significantly associated with increased fasting insulin concentration and visceral fat mass , decreased acute insulin response , beta cell function , and HDL cholesterol among African American children . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
We therefore investigated the effect of dietary polyunsaturated fat and vitamin E on the kinetics of HDL oxidation . ^^^ The polyunsaturated fat diet increased the mean HDL ( 2 ) lag time from 45 . 8+ / 12 . 5 to 83 . 3+ / 11 . 6 min with no change in oxidation rate . ^^^ We conclude that under conditions of controlled dietary fat intake , a high polyunsaturated fat intake does not increase the oxidation susceptibility of HDL subfractions , and that in this setting , vitamin E supplementation reduces the oxidation susceptibility of HDL ( 2 ) . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Calcium scores were positively correlated with intra abdominal adiposity , age , total cholesterol / high density lipoprotein ( HDL ) ratio , low density lipoprotein , triglycerides , blood pressure , and HOMA beta cell function and inversely correlated with HDL and peripheral fat . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Increased abdominal fat was associated with higher total cholesterol : HDL cholesterol , higher triglyceride concentration and increased diastolic blood pressure . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
However , when men and women were matched for HDL particle size and compared for their metabolic profile , it was found that both genders were characterized by similar plasma lipoprotein lipid profile despite the fact that women were characterized by higher levels of total body fat but lower waist girth than men . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Increased intra abdominal fat may lower HDL levels by increasing the fractional catabolic rate of Lp A 1 in postmenopausal women . ^^^ We conclude that intra abdominal fat may lower HDL levels by increasing the FCR of Lp A 1 , suggesting a mechanism by which central adiposity may be proatherogenic . . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
METHODS : Weight , body mass index ( BMI ) , total fat mass ( FM ) ( bioelectrical impedance ) , serum IGF 1 and fasting lipid profile ( total cholesterol , triglyceride , HDL cholesterol , LDL cholesterol ) were measured . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
We fed 634 baboons three diets to assess the separate effects of increasing dietary fat and cholesterol intakes on three independent measures of HDL phenotype : concentrations of HDL cholesterol and apoAI , and size distributions of HDL cholesterol . ^^^ Increasing dietary fat significantly increased concentrations of HDL cholesterol and apoAI ( both , P < 0 . 0001 ) , but did not affect HDL particle sizes , whereas increasing dietary cholesterol increased HDL cholesterol ( P < 0 . 0001 ) concentrations and HDL particle sizes ( P=0 . 08 ) , but did not affect apoAI concentrations . ^^^ However , genes exerted a smaller effect on HDL response to changes of dietary fat and of dietary cholesterol . ^^^ Therefore , dietary fat and cholesterol alter HDL levels and characteristics , but the dietary responses are not strongly mediated by additive genetic effects . . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
In multivariate regression models , trunk fat mass was associated with unfavorable levels of INS ( AUC ) , INS ( AUC ) xGLU ( AUC ) , TG , and HDL C , whereas leg fat mass was favorably associated with each of these variables . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
HDL decreased expression of macrophage CD 36 and aP 2 in a dose dependent manner . ^^^ HDL stimulated mitogen activated protein ( MAP ) kinase activity , and inhibition of CD 36 expression was blocked by co incubation with a MAP kinase inhibitor . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Univariate regression analysis showed that insulin resistance was positively correlated with subcutaneous ( r = . 544 , P < . 001 ) and visceral ( r = . 408 , P = . 001 ) fat areas , BMI ( r = . 324 , P = . 009 ) , HbA ( 1c ) ( r = . 254 , P = . 001 ) , serum triglycerides ( r = . 419 , P < . 001 ) , and serum LDL cholesterol ( r = . 290 , P = . 019 ) levels and was negatively correlated with serum HDL cholesterol level ( r = . 254 , P = . 041 ) . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
The following CVD risk factors were considered : lipoprotein levels ( total serum cholesterol ( TC ) , high density lipoprotein cholesterol ( HDL ) , the TC : HDL ratio , systolic and diastolic blood pressure , and indicators for body fatness and body fat distribution ( sum of four skinfolds , waist to hip ratio , waist circumference ) . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
We estimated HDL ( 1 ) cholesterol concentrations by gradient gel electrophoresis of serum samples obtained from 634 pedigreed baboons fed with three diets differing in levels of fat and cholesterol . ^^^ Segregation analyses yielded significant evidence that a single major gene plus polygenes affected HDL ( 1 ) on a high fat low cholesterol diet . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
There were no significant differences in BMI , percentage body fat , waist to hip ratio ( WHR ) , systolic blood pressure , diastolic blood pressure and concentrations of fasting plasma glucose , fasting serum insulin , serum low density lipoprotein ( LDL ) cholesterol , serum high density lipoprotein ( HDL ) cholesterol , serum triglyceride , and serum free fatty acids , according to ADRB 2 gene polymorphisms at codons 16 and 27 . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
The value of every indicator in fat metabolism of the cases who took quinestrol compound for 5 years was markedly higher than in the controls ( p0 . 001 in cholesterol , p0 . 05 in B LP , p0 . 01 in HDL ) . ^^^ Estrogen was associated with an increase of CL , HDL CL , and a decrease of LDL CL , while progesterone has little effect on the level of blood fat . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
OBJECTIVE : We describe changes in triacylglycerol , total cholesterol , HDL cholesterol , LDL cholesterol , insulin sensitivity ( S ( 1 ) ) , visceral fat , and subcutaneous abdominal adipose tissue ( SAAT ) with weight loss in premenopausal , overweight [ body mass index ( in kg / m ( 2 ) ) : 27 30 ] , African American ( n = 19 ) and white ( n = 18 ) women . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
HDL cholesterol was significantly lower with the almond diets ( P = 0 . 002 ) ; however , no significant effect of fat source on LDL : HDL was observed . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
POLY fat fed rabbits without alpha tocopherol supplementation had plasma HDL cholesterol concentrations that were less than half that of rabbits fed other fats , P < or = 0 . 0001 . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
The novel properties of a mutated receptor ( Q402R / Q418R , normal LDL binding but loss of most HDL binding ) were reproduced in the assay , as was the ability of the SR BI homologue CD 36 to bind HDL but not mediate efficient lipid uptake . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Experiments in CLA 1 ( CD 36 and LIMPII analogous 1 , the human homologue of scavenger receptor class B type 1 ) deficient HEK 293 cells demonstrated that EDL alone has the ability to stimulate HDL CE selective uptake independently of CLA 1 . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
CONCLUSIONS : These data indicate that short term weight loss resulting from reducing percentage energy from fat , increasing physical activity and vitamin / mineral supplements including folic acid has a favorable effect on regional body composition and total and LDL cholesterol with minimal effects on HDL cholesterol , triacylglycerols , homocysteine and insulin and the effects are greater in men compared to women . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Unexpectedly , t10c12 CLA increased insulin resistance ( 19 % ; P < 0 . 01 ) and glycemia ( 4 % ; P < 0 . 001 ) and reduced HDL cholesterol ( 4 % ; P < 0 . 01 ) compared with placebo , whereas body fat , sagittal abdominal diameter , and weight decreased versus baseline , but the difference was not significantly different from placebo . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
OBJECTIVE : To demonstrate relationships between plasma high density lipoprotein ( HDL ) cholesterol and fat expansions in the fat redistribution syndrome . ^^^ DESIGN : Patients who had significant buffalo humps or intra abdominal fat ( IAF ) expansions were identified and their HDL levels were measured . ^^^ Some patients answered a self administered questionnaire concerning self perceived fat expansions , and their responses were related to their HDL levels . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
The present day total physical activity had significant negative association with total cholesterol , ratio of total cholesterol to HDL cholesterol , LDL cholesterol , triglycerides , resting systolic blood pressure when controlling for the effects of age , body mass index and body fat percentages . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
To study whether HDL levels correlate with the ABCA 1 expression , wild type ( WT ) and the apoAI transgenic ( A 1 Tg ) mice were fed high fat ( HF ) diet with or without cholic acid ( CA ) for 3 weeks . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Recently , we found that replacement of saturated fat by trans fat in a dietary controlled study with 32 men and women decreased serum high density lipoprotein ( HDL ) cholesterol and impaired endothelial function , suggesting that trans fats have stronger adverse effects than saturated fats . ^^^ Thus , replacement of dietary saturated fat by trans fat not only decreased serum HDL cholesterol and impaired endothelial function , but also decreased the activity of serum paraoxonase . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
BACKGROUND : Gene nutrient interactions affecting high density lipoprotein cholesterol ( HDL C ) concentrations may contribute to the interindividual variability of the cardiovascular disease risk associated with dietary fat intake . ^^^ METHODS AND RESULTS : We have examined interaction effects between the 514 ( C / T ) LIPC polymorphism , dietary fat , and HDL related measures in 1020 men and 1110 women participating in the Framingham Study . ^^^ Thus , the T allele was associated with significantly greater HDL C concentrations only in subjects consuming < 30 % of energy from fat ( P < 0 . 001 ) . ^^^ When total fat intake was > or =30 % of energy , mean HDL C concentrations were lowest among those with the TT genotype , and no differences were observed between CC and CT individuals . ^^^ CONCLUSIONS : Dietary fat intake modifies the effect of the 514 ( C / T ) polymorphism on HDL C concentrations and subclasses . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
The pre exercise concentration of triacylglycerols was significantly lower on the high compared to the low fat diet ( mean + / s . d . 0 . 17 + / 0 . 06 and 0 . 23 + / 0 . 08 mmol / l , respectively ) , whereas the concentrations of cholesterol ( 3 . 00 + / 0 . 47 and 2 . 11 + / 0 . 49 mmol / l , respectively ) , HDL cholesterol ( 1 . 80 + / 0 . 18 and 1 . 35 + / 0 . 27 mmol / l , respectively ) and phospholipids ( 2 . 30 + / 0 . 11 and 1 . 72 + / 0 . 20 mmol / l , respectively ) were significantly higher . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
However , the total cholesterol : HDL cholesterol ratio was higher in treated mice ( P < 0 . 05 ) and HDL cholesterol was lower in HODE treated mice that were fed the low fat diet ( P < 0 . 05 ) . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
The effect of conjugated linoleic acid ( CLA ) on blood lipids [ total cholesterol , high density lipoprotein ( HDL ) , low density lipoprotein ( LDL ) and triacylglycerols ( TAG ) ] and the fatty acid distribution of the lipoprotein fractions , backfat , muscle fat , and liver lipids were examined in an experiment with two groups of 40 pigs [ Pietrain 10 ( Landrace 10 Large White ) ] each . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Adiponectin was significantly correlated with triglycerides ( r = 0 . 40 ) , abdominal visceral fat ( r = 0 . 35 ) , extremity fat ( r = 0 . 37 ) , insulin resistance ( HOMA IR ) ( r = 0 . 28 ) , nucleoside reverse transcriptase inhibitor ( NRTI ) use ( r = 0 . 32 ) , and high density lipoprotein ( HDL ) ( r = 0 . 41 ) using bivariate analysis ( all P < 0 . 01 ) . ^^^ This study indicates that adiponectin is inversely correlated with abdominal visceral fat mass , serum triglycerides , and insulin resistance and is directly correlated with HDL and extremity fat in a sample of HIV infected patients treated with HAART . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Comparison of SR BI with a related class B scavenger receptor , CD 36 , showed a greater uptake and a more rapid and extensive hydrolysis of HDL CE when delivered by SR BI . ^^^ These data indicate that SR BI , but not CD 36 , can efficiently direct HDL CE to a neutral CE hydrolytic pathway . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
After controlling for HRT status , % body fat was correlated with total cholesterol ( r = 0 . 43 , p = 0 . 001 ) , LDL C ( r = 0 . 38 , p = 0 . 003 ) , HDL C ( r = 0 . 29 , p = 0 . 025 ) , HDL 2 C ( r = 0 , 26 , p = 0 . 07 ) and TG levels ( r = 0 . 40 , p = 0 . 002 ) . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Increasing intra abdominal fat ( IAF ) area , quantified by computed tomography scan and decreasing S ( 1 ) , were important determinants of an atherogenic profile , marked by increased triglycerides , LDL cholesterol , and apolipoprotein B and decreased HDL cholesterol and LDL buoyancy ( Rf ) . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
The serum LDL / HDL cholesterol ratio is influenced more favorably by exchanging saturated with unsaturated fat than by reducing saturated fat in the diet of women . ^^^ We conclude that , to influence the LDL / HDL cholesterol ratio , changing the proportions of dietary fatty acids may be more important than restricting the percentage of total or saturated fat energy , at least when derived mainly from lauric and myristic acids , both of which increase HDL cholesterol . . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
OBJECTIVE : CD 36 has been proposed as a fatty acid translocase and a receptor for HDL and oxidized LDL . ^^^ Regardless of diabetes , HDL cholesterol concentrations in the CD 36 deficient patients were significantly higher than in the control subjects . ^^^ Lipid abnormalities in CD 36 deficiency may partly depend on the presence of diabetes , and increased levels of triglyceride and HDL cholesterol may be due to impaired binding of fatty acids and HDL to CD 36 and subsequent clearance . . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
When carbohydrates are used to replace saturated fats , in a low fat diet , LDL and HDL decrease similarly , and the ratio is not improved ; triglycerides increase as well when carbohydrate increases , except when low glycemic index foods are used . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Liver fat content ( spectroscopy ) , serum insulin , C peptide and triglyceride concentrations were significantly higher , and HDL cholesterol concentration lower in the HAART+LD+ than the HAART+LD group . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
The study provides extensive information on selected anthropometrical and biochemical parameters , especially on those , which are generally used as risk indices for the origin and development of cardiovascular disease ( CVD ) : body mass index ( BMI ) , body fat percentage ( b . fat ) , waist circumference ( waist ) , serum concentrations of total cholesterol ( Tchol ) , HDL and LDL cholesterol ( HDL chol , LDL chol ) , triacylglyceroles ( TAG ) and the atherogenic index ( AI ) . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Exogenous androgens induce both apparently beneficial and deleterious effects on cardiovascular risk factors by decreasing serum levels of HDL C , plasminogen activator type 1 ( apparently deleterious ) , lipoprotein ( a ) , fibrinogen , insulin , leptin , and visceral fat mass ( apparently beneficial ) in men as well as women . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
In women , fasting serum ferritin concentrations correlated significantly with age , body mass index ( BMI ) , amount of body fat , fasting plasma glucose , insulin , cholesterol , triglyceride concentrations , glucose response to an oral glucose load , and homeostasis model assessment ( HOMA ) of insulin resistance but not with blood pressure , high density lipoprotein ( HDL ) cholesterol levels and insulin response to oral glucose . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
In the present study the effects of dietary fat with defined fatty acids on lecithin : cholesterol acyltransferase ( LCAT ) and apoA 1 , the two components of HDL that play a major role in reverse cholesterol transport ( RCT ) , were examined . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
FINDINGS : A model including age , sex , duration of HIV infection , HIV disease stage , waist to hip ratio , anion gap , serum HDL cholesterol concentration , trunk to peripheral fat ratio , percentage leg fat , and intra abdominal to extra abdominal fat ratio had 79 % ( 95 % CI 70 85 ) sensitivity and 80 % ( 95 % CI 71 87 ) specificity for diagnosis of lipodystrophy . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Nineteen nonsmoking , healthy men ( n = 11 ) and women ( n = 8 ) not receiving lipid altering medications completed dietary surveys , and had percent body fat determinations , and fasting blood drawn for measurements of plasma lipids , lipoproteins , apolipoprotein A 1 ( Apo A 1 ) , and absolute and percent prebeta 1 HDL . ^^^ Mean + / SD values were determined for age , percent body fat , dietary calories , dietary cholesterol , dietary fat , and plasma lipids , lipoproteins , Apo A 1 , and absolute and percent prebeta 1 HDL using 1 way analysis of variance ( ANOVA ) . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
No differences were observed in relation to energy , fat , protein and carbohydrate daily intakes , total cholesterol , HDL , LDL , uric acid , and serum creatinine levels . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
DESIGN : We performed a meta analysis of 60 selected trials and calculated the effects of the amount and type of fat on total : HDL cholesterol and on other lipids . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
With respect to plasma lipoprotein profiles , relatively consistent evidence indicates that under isoweight conditions , decreasing the total fat content of the diet causes an increase in triglyceride and decrease in high density lipoprotein ( HDL ) cholesterol levels . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
High insulin levels were related to greater percentage body fat , dietary carbohydrate and fat intake , lower high density lipoprotein ( HDL ) cholesterol ( in men ) , higher total cholesterol ( in women ) , and a trend toward higher triglycerides . ^^^ Cardiovascular reactivity findings were unchanged after statistical adjustment for total and HDL cholesterol , triglycerides , percentage body fat , dietary carbohydrates , and fat . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
RESULTS : Daily calcium intake was negatively correlated with plasma LDL cholesterol , total cholesterol , and total : HDL cholesterol in women and men after adjustment for variations in body fat mass and waist circumference ( P < 0 . 05 ) . ^^^ In women , a significantly greater ratio of total to HDL cholesterol ( P < 0 . 05 ) was observed in group A than in group C after correction for body fat mass and waist circumference . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
The mean HDL level correlated negatively with visceral fat and preperitoneal fat thickness . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
MEASUREMENTS : Four measurements of fat : body mass index ( BMI , kg / m ( 2 ) ) , body fat percentage measured using a dual energy 10 ray absorptiometry ( DEXA ) scanner , waist / hip circumference ratio ( WHR ) , and intra abdominal adipose tissue area measured using computed tomography ( CT ) scanning , and eight metabolic risk factors : systolic and diastolic blood pressure , HbA ( 1c ) percentage , fasting concentrations of capillary whole blood glucose , high density lipoprotein ( HDL ) cholesterol , serum triglyceride , plasma plasminogen activator inhibitor 1 ( PAI 1 ) , and urinary albumin : creatinine excretion ratio . ^^^ In multiple regression analyses of the four fat variables , only intra abdominal adipose tissue area significantly predicted the levels of six metabolic risk factors : systolic blood pressure , diastolic blood pressure , fasting concentrations of capillary whole blood glucose , serum HDL cholesterol , serum triglyceride , and PAI 1 . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
The T111I mutation in the EL gene modulates the impact of dietary fat on the HDL profile in women . ^^^ The objective of the present study was to examine the impact of the T111I missense mutation in exon 3 of the endothelial lipase ( EL ) gene on HDL and its potential interaction effect with dietary fat . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Replacing 40 % of dietary animal fat with vegetable oil is associated with lower HDL cholesterol and higher cholesterol ester transfer protein in cynomolgus monkeys fed sufficient linoleic acid . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Exogenous androgens , on the other hand , induce both apparently beneficial and deleterious effects on cardiovascular risk factors by decreasing serum levels of HDL C , PAI 1 ( apparently deleterious ) , Lp ( a ) , fibrinogen , insulin , leptin and visceral fat mass ( apparently beneficial ) in men as well as women . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Recent studies using prescribed diets with a difference of < / = 15 % of energy in total fat between low fat and high MUFA diets show similar effects on glycemic profiles but still favor MUFA diets for effects on triacylglycerols and HDL cholesterol . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
An isoenergetic very low carbohydrate diet improves serum HDL cholesterol and triacylglycerol concentrations , the total cholesterol to HDL cholesterol ratio and postprandial pipemic responses compared with a low fat diet in normal weight , normolipidemic women . ^^^ Compared with the low fat diet , the very low carbohydrate diet increased ( P < or= 0 . 05 ) fasting serum total cholesterol ( 16 % ) , LDL cholesterol ( LDL C ) ( 15 % ) and HDL C ( 33 % ) and decreased serum triacylglycerols ( 30 % ) , the total cholesterol to HDL ratio ( 13 % ) and the area under the 8 h postprandial triacylglycerol curve ( 31 % ) . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
In Experiment 1 , rats fed all types of oxidized fats had higher concentrations of HDL cholesterol and lower ratios between plasma and HDL cholesterol than rats fed the diet containing the fresh fat . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Analyses were restricted to Mexican American men aged 40 74 years with data on glycated hemoglobin ( % ) , body mass index ( BMI ) , body fat distribution , HDL cholesterol , fasting serum insulin , serum triglycerides and serum tHcy concentrations . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Long term low fat diet consumption with or without olestra does not decrease HDL cholesterol . . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Both intra abdominal fat and adiponectin contributed independently to triglycerides , HDL cholesterol and Rf . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
INTERPRETATION : There is indication that HDL cholesterol also plays a role in the complex interaction of fat intake , metabolism and the manifestation of atopy in adults . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
In antiretroviral ( ARV ) naive patients enrolled in the Fat Redistribution and Metabolic Substudy ( FRAMS ) of the Atlantic Study , the NVP containing regimen increased total cholesterol , high density lipoprotein ( HDL ) cholesterol concentration and particle size and apolipoprotein A 1 ( apo A 1 ) levels at 24 weeks . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
OBJECTIVE : To determine the effect in children with intractable seizures of a high fat ketogenic diet on plasma levels of the major apolipoprotein B ( apoB ) containing lipoproteins , low density lipoprotein ( LDL ) and very LDL ( VLDL ) ; and the major apolipoprotein A 1 ( apoA 1 ) containing lipoprotein , high density lipoprotein ( HDL ) . ^^^ RESULTS : At 6 months , the high fat ketogenic diet significantly increased the mean plasma levels of total ( 58 mg / dL [ 1 . 50 mmol / L ] ) , LDL ( 50 mg / dL [ 1 . 30 mmol / L ] ) , VLDL ( 8 mg / dL [ 0 . 21 mmol / L ] ) , and non HDL cholesterol ( 63 mg / dL [ 1 . 63 mmol / L ] ) ( P < . 001 vs baseline for each ) ; triglycerides ( 58 mg / dL [ 0 . 66 mmol / L ] ) ( P < . 001 ) ; and total apoB ( 49 mg / dL ) ( P < . 001 ) . ^^^ CONCLUSIONS : A high fat ketogenic diet produced significant increases in the atherogenic apoB containing lipoproteins and a decrease in the antiatherogenic HDL cholesterol . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Ghrelin was also inversely related to systolic and diastolic blood pressure ( r= . 29 and r= 0 . 34 , respectively , P < . 01 ) and positively to high density lipoprotein ( HDL ) cholesterol ( 0 . 33 , P < . 01 ) , and low density lipoprotein ( LDL ) particle size ( 0 . 34 , P < . 001 ) , but these associations did not remain after adjustment for body fat . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
With this in mind , we designed a cross over double blind placebo controlled study of 12 men aged 59 . 0 + / 4 . 8 years , who received either 50 mg / 24 h DHEA or placebo for 3 months to assess the influence of DHEA on the content and distribution of fat tissue and serum insulin , glucose , total cholesterol , low density lipoprotein ( LDL ) cholesterol and high density lipoprotein ( HDL ) cholesterol levels , as well as testosterone , estradiol , DHEA sulfate ( S ) , prostate specific antigen ( PSA ) concentrations and indexes of insulin sensitivity and resistance . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Adiponectin was inversely correlated with percent body fat , waist circumference , HOMA IR , and triglyceride and positively correlated with HDL ( r = |0 . 30| |0 . 44| , all P < 0 . 0001 ) . ^^^ In multivariate linear regression analysis in nondiabetic subjects , HDL and percent body fat were significantly related to adiponectin variation among both men and women ( R ( 2 ) = 28 29 % ) . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
In the IG , lower back pain , body fat , and blood pressure were all reduced , while the self reported quality of life , endurance exercise capacity and HDL cholesterol were increased . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
In spite of an adequate total fat intake ( 25 en % ) , the relatively low intake of PUFAs in association with a high carbohydrate diet ( 65 en % ) , appear to be resulting in similar metabolic outcomes to those of very low fat diets ( VLFD , < 15 en % from fat ) , as reflected by high triglycerides and low HDL levels . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
MEASUREMENTS : Body composition and fat distribution ( by bioelectrical impedance analysis and anthropometry ) , systolic and diastolic blood pressure , plasma glucose , total and HDL cholesterol , triglycerides , insulin and insulin resistance by HOMAir , various weight cycling indices . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Three messages can be summarized from these experiments ; ( 1 ) endocytic uptake of OxLDL and AGE proteins by macrophages or macrophage derived cells is mainly mediated by SR A and CD 36 , which is an important step for foam cell formation in the early stage of atherosclerosis , ( 2 ) selective uptake of cholesteryl esters of high density lipoprotein ( HDL ) mediated by SR BI is inhibited by AGE proteins , suggesting a potential pathological role of AGE in a HDL mediated reverse cholesterol transport system , ( 3 ) a novel scavenger receptor is involved in hepatic clearance of plasma OxLDL and AGE proteins . . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Peak aerobic capacity ( VO ( 2max ) / kg ) was predicted by body fat distribution , insulin sensitivity index , and high density lipoprotein ( HDL ) and low density lipoprotein ( LDL ) cholesterol ( p < 0 . 001 ) . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
The reduced fat diet lowered total cholesterol ( P < 0 . 01 ) , LDL cholesterol ( P < or =0 . 05 ) , total cholesterol : HDL ratio ( P < or =0 . 05 ) , body weight ( P < 0 . 01 ) and systolic blood pressure ( P < or =0 . 05 ) initially and diastolic blood pressure ( P < 0 . 01 ) long term . ^^^ It was concluded that a reduced fat ad libitum diet has short term benefits for cholesterol , body weight and systolic blood pressure and long term benefits for diastolic blood pressure without significantly effecting HDL cholesterol and triglycerides despite participants regaining their lost weight . . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
RESULTS : The presence of CAD was associated with current , past or passive smoking , a history of diabetes and high blood pressure , a positive family risk factors in this study ; levels were below history of CAD , body fat percentage , waist hip ratio ( WHR ) , low apolipoprotein A 1 or low HDL , lipoprotein ( a ) , glucose , insulin , insulin resistance , C reactive protein ( CRP ) , total cholesterol to HDL ratio ( TC / HDL ) and creatinine on univariate conditional logistic regression analysis . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Plasma triacylglycerol and HDL cholesterol concentrations confirm self reported changes in carbohydrate and fat intakes in women in a diet intervention trial . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Hamsters fed diets high in saturated fat have increased cholesterol accumulation and cytokine production in the aortic arch compared with cholesterol fed hamsters with moderately elevated plasma non HDL cholesterol concentrations . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Previous studies in weight stable persons showed that a moderate fat diet results in a more favorable lipid and lipoprotein profile ( ie , lower serum triacylglycerol and higher HDL cholesterol ) than does a low fat diet . ^^^ Compared with baseline , HDL cholesterol was unchanged , whereas triacylglycerol and the ratios of total and non HDL cholesterol to HDL cholesterol were lower at the end of the weight maintenance period in the moderate fat diet group . ^^^ Despite similar weight loss , triacylglycerol rebounded , HDL cholesterol decreased , and the ratios of total and non HDL cholesterol to HDL cholesterol did not change during the 10 wk interval in the low fat diet group . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
CONCLUSIONS : Within the context of a diet high in dairy fat ( 50 g / day ) , replacing cows ' milk fat with sheep ' s milk fat leads to a small reduction in plasma cholesterol concentration , but no change in the ratio of LDL to HDL cholesterol . . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
High consumption of dietary linolenic acid was associated with young age ; high intakes of energy , fat , carbohydrates , fruit , vegetables , and fish ; low HDL cholesterol ; current smoking ; and frequent consumption of creamy salad dressing . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Most of these relationships ( triglycerides , HDL cholesterol , LDL / HDL cholesterol ratio in women , and all measured lipids in men ) remained statistically significant ( P values ranging from 0 . 000 to 0 . 03 ) when the BMD values were adjusted also for anthropometric measures ( body weight , height , fat mass ) . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Compared with the 50 % fat diet , subjects consuming the 19 % fat diet had significantly lower HDL cholesterol ( HDL C ) ( 54 + / 3 vs . 63 + / 3 mg . dL ( 1 ) , p < 0 . 05 ) and apolipoprotein A 1 ( ApoA 1 ) ( 118 + / 4 vs . 127 + / 3 mg / dL , p < 0 . 05 ) . ^^^ Changing the levels of fat intake did not affect % body fat , heart rate , blood pressure , blood triglycerides , total cholesterol ( TC ) , LDL cholesterol , apolipoprotein B ( ApoB ) , TC / HDL C and ApoA1 / ApoB ratios . ^^^ CONCLUSION : A low fat diet ( 19 % ) may not provide sufficient calories , essential fatty acids , and some micronutrients ( especially vitamin E and zinc ) for healthy untrained individuals , and it also lowered ApoA 1 and HDL C . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
The short term hypoenergetic low fat diet was more effective at lowering serum LDL C , but the very low carbohydrate diet was more effective at improving characteristics of the metabolic syndrome as shown by a decrease in fasting serum TAG , the TAG / HDL C ratio , postprandial lipemia , serum glucose , an increase in LDL particle size , and also greater weight loss ( P < 0 . 05 ) . . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Patients also underwent a study protocol including measurements of BMI , waist to hip ratio ( WHR ) , resting energy expenditure ( REE ) , energy intake , fat mass ( FM ) and free fat mass ( FFM ) , total cholesterol ( TCH ) , high density lipoprotein ( HDL ) cholesterol , triacylglyceroles ( TG ) , leptin levels , basal glucose , immunoreactive insulin ( IRI ) , glycated haemoglobin ( HbA1c ) , insulin sensitivity and thyroid hormones . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
The following parameters were examined at baseline , 10 wk , and 36 wk ( cohort 1 only ) : Weight , height , percentage of ideal body weight ( % IBW ) , relative body fat ( % fat ) , fat free body ( FFB ) mass , estimated VO ( 2 ) max mL / kg min ( BW ) [ adjusted for body weight ] ) , blood chemistries , lipid profiles ( total cholesterol [ TC ] , triglycerides [ TG ] , low density lipoprotein [ LDL ] , high density lipoprotein [ HDL ] , and insulin like growth factor 1 [ IGF 1 ] ) . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Protein and lipid components of blood serum high density lipoproteins ( HDL ) responsible for their functional activity were studied before and after fat load in subjects with normal body mass and various types of obesity . ^^^ Fat load caused changes of HDL composition in all study groups . ^^^ Contrary to subjects with normal body mass and gluteo femoral obesity fat load induced changes of HDL components in persons with abdominal obesity were not associated with augmented acceptor capacity of HDL what could be considered as proatherogenic effect . . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
METHODS : In the Third National Health and Nutrition Examination Survey , adolescents aged 12 to 16 years ( n = 941 ) had parental medical history ascertained and glycated hemoglobin , systolic blood pressure , body mass index ( BMI ) , body fat distribution , HDL cholesterol , and serum tHcy concentrations were measured . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Similarly , CD 36 and FATP 1 expression correlated with acquired differences in HDL cholesterol and non esterified fatty acid concentrations respectively . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
In analyses controlling for genetic influences in monozygotic twins , within pair differences in CRP were associated with within pair differences in total body fat ( r=0 . 39 , P < 0 . 001 ) , CAF ( r=0 . 34 , P=0 . 002 ) , diastolic blood pressure ( r=0 . 24 , P=0 . 03 ) , apolipoprotein AI ( r= 0 . 33 , P=0 . 01 ) , HDL cholesterol ( r= 0 . 42 , P=0 . 001 ) , and triglycerides ( r=0 . 35 , P=0 . 007 ) . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Test fat `` F ' ' contained 5 g / 100 g long chain ( n 3 ) fatty acids matched by oleic acid in test fat `` O . ' ' Plasma total triacylglycerol ( TAG ) , VLDL TAG , cholesterol in VLDL , and intermediate density lipoproteins ( IDL ) were lower ( P < 0 . 05 ) , whereas apolipoprotein ( apo ) B of the large LDL 2 ( d = 1031 1042 g / L ) subclass , and cholesterol of HDL ( 2b ) subclass , were higher after intake of F than O fat ( P < 0 . 05 ) . ^^^ In conclusion , a solid dietary fat containing ( n 3 ) PUFA decreased plasma TAG , VLDL , and IDL cholesterol , and redistributed lipoprotein subclasses in LDL and HDL , with a higher concentration of the larger and less atherogenic subfractions . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
In a multiple regression analysis including all variables that showed significant univariate associations with adiponectin , associations of adiponectin with HDL cholesterol ( beta = 0 . 079 , P = . 0009 ) , percent body fat ( beta = 0 . 165 , P = . 002 ) , and serum leptin ( beta = 0 . 291 , P = . 01 ) were statistically significant . ^^^ HDL cholesterol ( beta = 0 . 077 , P = . 001 ) , percent body fat ( beta = 0 . 078 , P = . 03 ) , and LDL size ( beta = 0 . 092 , P = . 03 ) emerged as significant and independent determinants of adiponectin after HOMA IR , fasting glucose , triglycerides , and systolic blood pressure ( BP ) were taken into account . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
The aim of this study was to assess the influence of bioflavonoids from the radix of Scurellaria baicalensis on the level of lipids , via the determination of the concentrations of triglycerides , total cholesterol and high density lipoprotein ( HDL ) cholesterol in the plasma of laboratory rats fed high fat and high cholesterol diets , and via the calculation of their atherogenic index . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Among obese individuals , those who accumulate fat predominantly in the abdominal area are more likely to present several metabolic perturbations of the metabolic syndrome , such as increased plasma triacylglycerol and apolipoprotein B concentrations , an elevated ratio of total cholesterol to HDL cholesterol , reduced plasma HDL cholesterol concentrations , and small , dense LDL particles . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Although scavenger receptor BI and CD 36 bind many of the same ligands , these two receptors have very specific lipid transport functions : CD 36 facilitates the uptake of long chain fatty acids and SR BI mediates the transport of cholesterol and cholesteryl ester from HDL particles . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
The anti obesity effect of PM F 2 OB on rats fed a high fat diet was investigated through analyses of changes in body weight , kidney fat weight , and blood biochemicals including cholesterol , free fatty acid , BUN , creatinine , HDL , LDL , phospholipids , SGOT , SGPT , total lipids , and triglycerides . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Men and women with similar amounts of intra abdominal and liver fat do not exhibit sex differences in markers of insulin resistance ( serum insulin , triglycerides , HDL cholesterol and adiponectin ) . . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
At the same time , all childrens ' serum triglyceride ( TG ) , total cholesterol ( TC ) , high density lipoprotein cholesterol ( HDL C ) , low density lipoprotein cholesterol ( LDL C ) , height and weight were measured , and their body mass index ( BMI ) and fat percent ( % fat ) were calculated . ^^^ The concentration of serum TG and the BMI and % fat of the A / A genotype obesity children were higher than those of the G / G genotype ones ( P < 0 . 01 ) but the level of serum HDL of the A / A children were lower than that of the G / G children ( P < 0 . 01 ) . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
To evaluate such an effect of MP , we analyzed whether the plasma levels of low density lipoprotein ( LDL ) cholesterol , high density lipoprotein ( HDL ) cholesterol , and body weight change after rats were fed on high fat diet with MP for 8 weeks . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
After adjustment for body fat mass , plasma adiponectin remained lower in pGDM ( P < 0 . 004 ) and correlated positively with S ( 1 ) ( P < 0 . 003 ) and HDL cholesterol ( P < 0 . 0001 ) but negatively with plasma glucose ( 2 h oral glucose tolerance test [ OGTT ] ) ( P < 0 . 0001 ) , leptin ( P < 0 . 01 ) , CRP ( P < 0 . 007 ) , and PAI 1 ( P < 0 . 0001 ) . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
These abnormalities may be consequent on a global metabolic effect of insulin resistance , partly mediated by depressed plasma adiponectin levels , that collectively increases the flux of fatty acids from adipose tissue to the liver , the accumulation of fat in the liver and skeletal muscle , the hepatic secretion of VLDL triacylglycerols and the remodelling of both LDL ( low density lipoprotein ) and HDL particles in the circulation . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Our data indicate that within the context of a diet restricted in fat and cholesterol , a higher fish content favorably affects VLDL and HDL subspecies . . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
METHODS AND RESULTS : The kinetics of apoA 1 within high density lipoprotein ( HDL ) , apoB 48 and apoB 100 within triglyceride rich lipoproteins , and apoB 100 within intermediate density lipoprotein and low density lipoprotein ( LDL ) were examined with a primed constant infusion of [ 5 , 5 , 5 ( 2 ) H ( 3 ) ] leucine in the fed state ( hourly feeding ) in 23 subjects after consumption of a 36 % total fat diet . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
CONCLUSIONS : Addition of cholesterol to a high fat diet increased plasma SAA levels and atherosclerosis independent of an adverse effect on plasma lipoproteins , consistent with the hypothesis that SAA may promote atherosclerosis directly by mediating retention of SAA enriched HDL to vascular proteoglycans . . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Including walnuts in a low fat / modified fat diet improves HDL cholesterol to total cholesterol ratios in patients with type 2 diabetes . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Extent of intra abdominal fat had significant linear relations with six metabolic coronary risk factors : systolic and diastolic blood pressure , fasting blood concentrations of glucose , high density lipoprotein ( HDL ) cholesterol , triglyceride , and plasminogen activator inhibitor 1 . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
CONCLUSION : There is a significant decrease of T . cho , TG , LDL C and non HDL C levels with no significant increase of HDL C in the intervention group with the fat modified diet . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
A scavenger receptor of the B class ( SR BI ) / human homolog of SR BI , CD 36 , and LIMPII analogous 1 ( CLA 1 ) facilitates the cellular uptake of cholesterol from HDL and thus augments cell growth . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
OBJECTIVE : To establish a new drug screening model based on transcriptional regulation of human high density lipoprotein ( HDL ) receptor gene CD 36 and LIMPII analogous 1 ( CLA 1 ) for discovering up regulator of this receptor . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
In particular , visceral fat accumulation is usually accompanied by insulin resistance or type 2 diabetes mellitus , hypertension , hypertriglyceridemia , high uremic acid levels , low high density lipoprotein ( HDL ) cholesterol to define a variously named syndrome or metabolic syndrome . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
The very favorable effects of very low fat , whole food , quasi vegan diets on LDL cholesterol , insulin sensitivity , and body weight appear to more than compensate for this decrease in HDL ; it is notable that HDL levels tend to be quite low in Third World cultures at minimal risk for coronary disease . ^^^ On the other hand , this decrease in HDL may be of more significance in the context of omnivore diets only moderately low in fat , as suggested by the fact that diets higher in unsaturated fats emerge as more protective in Western prospective epidemiology . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Filipinas were younger ( 64 . 4 versus 66 . 7 years ) , had higher triglyceride levels ( 155 versus 135 mg / dL ) , had a higher ratio of total cholesterol to HDL cholesterol ( 4 . 3 versus 3 . 5 ) , more frequently used statins ( 31 % versus 19 % ) , and had more visceral fat ( 69 . 4 versus 62 . 1 cm 3 ) and lower HDL cholesterol levels ( 54 versus 66 mg / dL ) than whites . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Human scavenger receptor class B type 1 ( SR BI ; CD 36 and lysosomal integral membrane protein 2 analogous 1 [ CLA 1 ] ) plays a central role in HDL mediated native and oxidized cholesteryl ester uptake . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Adiponectin plasma level correlated negatively ( p < 0 . 05 ) with BMI , waist , percentage of total fat , fasting insulin resistance index ( FIRI ) , total cholesterol and triglycerides , and positively with quantitative insulin sensitivity check index ( QUICKI ) , HDL cholesterol , total testosterone , and total testosterone / estradiol ratio . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
CONCLUSION : The fat modified milk seems to have positive effects on the LDL / HDL ratio and the LP ( a ) concentrations , both of which have been established as risk factors for coronary heart disease . . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
OBJECTIVE : It is unknown whether a low fat diet , which may elevate triglycerides and lower high density lipoprotein ( HDL ) cholesterol , harms the endothelium . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
In addition , bodyweight , body mass index , subcutaneous fat thickness , total cholesterol , high density lipoprotein ( HDL ) cholesterol , and triglyceride were measured . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
RESULTS : For a given level of waist circumference , visceral fat , or subcutaneous fat , the high CRF group had lower triglyceride levels ( P < 0 . 05 ) and higher HDL cholesterol levels than the low or moderate CRF groups . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Mean levels of body mass index ( BMI ) , total cholesterol , LDL cholesterol , HDL cholesterol , daily percent calories from fat and saturated fat , daily servings of fruits and vegetables , and daily fiber intake were examined across three physical activity levels and two fitness categories . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Fasting triglycerides , total cholesterol , and LDL cholesterol as well as HDL cholesterol levels in high fat diet treated rats and hamster were determined . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Age , sex , smoking status , weight , height , waist circumference , blood pressure , antihypertensive treatment , total cholesterol , HDL cholesterol , triglycerides , and glucose concentrations , in addition to changes in body fat distribution were measured in 31 HIV infected patients with no antiretroviral therapy , 35 HIV infected patients treated with protease inhibitor sparing regimens , and 153 HIV infected patients treated with protease inhibitor containing regimens . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
RESULTS : Controlling for trunk fat revealed a favorable effect of leg fat on INS 0 , INS ( AUC ) , INS ( AUC ) 10 GLU ( AUC ) , TG , and HDL . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Plasma PAI 1 , t PA , and glucose as well as serum C peptide , insulin , total cholesterol , triglyceride , and HDL and LDL cholesterol levels were measured at 0 , 2 , 4 , and 6 h after the fat load . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
CONCLUSIONS : These results collectively indicate that plasma HDL cholesterol levels and visceral fat masses are independently associated with plasma adiponectin concentrations . . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
BP 2 shared many of the effects of E 2 by suppressing LH , cholesterol , LDL , HDL and the size of a small estrogen regulated fat depot in the lower hindleg . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
BACKGROUND : Normal chow ( low fat ) fed mice deficient in both the HDL receptor SR BI and apolipoprotein E ( SR BI / apoE dKO ) provide a distinctive model of coronary heart disease ( CHD ) . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
In the stepwise regression model significant independent correlates for systolic BP were CRP , FB , VCAM 1 , HOMA IR , LDL cholesterol and fat mass , whereas CRP , IL 6 , ICAM 1 , FB , LDL and HDL cholesterol were the determinants of diastolic BP in children with obesity related hypertension . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
High fat diet fed rats showed significant increased levels of plasma and tissue total cholesterol , triglycerides , free fatty acids , phospholipids , plasma LDL cholesterol and decreased level of plasma HDL cholesterol . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
On the other hand , HDL exposure reduced intracellular cholesterol content to 70 % , and caused an increase in the expression of CD 36 ( 78 % ) , SR A ( 51 % ) and CLA 1 ( 136 % ) . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Scavenger receptor class B type 1 ( SR BI ) , a CD 36 family member , plays a key role in high density lipoprotein ( HDL ) metabolism , reverse cholesterol transport , and whole body cholesterol homeostasis , and is shown to be involved in the development of atherosclerosis in mice . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Body weight decreased by 1 . 2 kg ( P < 0 . 001 ) , waist circumference by 2 . 8 cm ( P < 0 . 001 ) , percent body fat by 1 . 4 % ( P < 0 . 001 ) , and the homeostasis model assessment index of insulin resistance by 0 . 31 U ( P < 0 . 01 ) ; HDL cholesterol increased by 0 . 032 mmol / L ( 1 ) ( P < 0 . 05 ) . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
The former also had significantly higher values for body mass index ( BMI ) , visceral fat , diastolic blood pressure , HOMA insulin resistance score , plasma insulin ( both fasting and after glucose load ) , triglycerides , liver enzymes , and lower high density lipoprotein ( HDL ) cholesterol concentration . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Regression analysis of Ramadan HDL cholesterol levels indicated positive association with pulse rate and fat intake and negative association with systolic blood pressure and weight loss . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
MEASUREMENTS : Measurements included age , the fat ( FMI ) and fat free mass ( FFMI ) components of BMI , high density lipoprotein ( HDL C ) , low density lipoprotein ( LDL C ) , triglycerides ( TG ) , total cholesterol ( TC ) , fasting glucose and insulin , physical activity , alcohol use and smoking , and women ' s menopausal status and estrogen use . ^^^ CONCLUSIONS : ( 1 ) Age is an important independent predictor for LDL C and TC in men , and TC in women , but it is not as influential as body composition and lifestyle on HDL C and TG in men and women , and LDL C in women . ( 2 ) Increasing FMI is the major contributor to elevated TC , LDL C and TG levels , and decreased HDL C levels in men and women . ( 3 ) FFMI significantly influences HDL and TG levels in both sexes . ( 4 ) Maintaining a lower BMI via a reduced fat component may be more beneficial in lowering CVD risks than other factors . . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
The total body fat mass and serum concentration of total cholesterol , HDL cholesterol , and triglyceride ( TG ) differ between standard diet fed female inbred mouse strains MRL / MpJ ( MRL ) and SJL / J ( SJL ) by 38 120 % ( P < 0 . 01 ) . ^^^ In summary , linkage analysis in MRL 10 SJL F 2 mice disclosed novel loci affecting TG , HDL , and fat mass , a measure of obesity . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Influence of dietary carbohydrate and fat on LDL and HDL particle distributions . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Most consistent are greater changes in high density lipoprotein ( HDL ) , HDL 2 , and apolipoprotein A 1 levels in women compared with men with high carbohydrate or high fat feeding . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
OBJECTIVE : To develop a new high throughput screening model for human high density lipoprotein ( HDL ) receptor ( CD 36 and LIMPII analogous 1 , CLA 1 ) agonists using CLA 1 expressing insect cells . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
A low saturated fat , low cholesterol diet decreases plasma CETP activity and pre beta HDL formation but does not affect cellular cholesterol efflux to plasma from type 1 diabetic patients . ^^^ The aim of this study was to evaluate the effect of a low saturated fat , low cholesterol diet on plasma lipopoproteins , pre beta high density lipoprotein ( HDL ) formation , lecithin : cholesterol acyltransferase ( LCAT ) , cholesteryl ester transfer protein ( CETP ) and phospholipid transfer protein ( PLTP ) activities , as well as on the ability of plasma to stimulate cellular cholesterol efflux . ^^^ Reduction in dietary saturated fat and cholesterol intake does not adversely affect cellular cholesterol efflux to plasma from type 1 diabetic patients , despite a drop in pre beta HDL formation . . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
There were no differences in serum cholesterol , HDL , or triglyceride levels due to fat substitute diet . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Significantly greater amounts of intra abdominal fat ( p=0 . 045 ) measured by computed tomography were found in the men with phenotype B while fasting insulin ( p=0 . 070 ) and triglycerides ( p=0 . 051 ) tended to be higher . free fatty acids ( r=0 . 677 ) , LDL density ( relative flotation rate , r= 0 . 803 ) , and plasma HDL cholesterol ( r= 0 . 717 ) . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
One hundred forty six healthy male subjects 30 71 years were evaluated for IAF and subcutaneous fat ( computed tomography scan at 4th lumbar vertebra ) , height , body weight , % fat , various anthropometric measures , blood cholesterol ( CHOL ) , HDL cholesterol ( HDL ) , systolic blood pressure ( SBP ) , and diastolic blood pressure ( DBP ) . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
We hypothesize that saturation of the subcutaneous fat depot is the primary event in the pathophysiology of insulin resistance in the majority of patients and postulate that this seminal event may lead to the development of hypertension , hypertriglyceridemia and depressed HDL levels ( i . e . , the metabolic syndrome ) . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Both diets lead to improvements in risk factors for coronary heart disease , the low carbohydrate diet leading to a greater decrease in serum triglycerides and increase in HDL cholesterol compared to the low fat diet . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Among the central mechanisms mediating the effect of physical activity are ( a ) increased insulin sensitivity , ( b ) a non insulin dependent glucose uptake , which causes lower insulin release , ( c ) an improved ratio between HDL and LDL cholesterol because of increased activity of lipoprotein lipase , and d ) improved function of other metabolic hormones and enzymes for fat metabolism . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Changes in trunk fat were positively correlated with medium VLDL ( r=0 . 474 , P < 0 . 0 ) and small LDL ( r=0 . 405 , P < 0 . 05 ) and negatively correlated with large HDL ( r= 0 . 556 , P < 0 . 01 ) . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Total cholesterol ( r=0 . 134 , p < 0 . 05 ) , LDL ( r=0 . 140 , p < 0 . 05 ) , HDL ( r= 0 . 181 , p < 0 . 001 ) , total cholesterol to HDL ratio ( r=0 . 240 , p < 0 . 001 ) and triglyceride ( r=0 . 300 , p < 0 . 001 ) concentrations had the strongest correlation to percent of total body fat in the trunk in women . ^^^ Total cholesterol ( r= 0 . 151 , p < 0 . 05 ) , total cholesterol to HDL ratio ( r=0 . 216 , p < 0 . 001 ) , and triglyceride ( r=0 . 227 , p < 0 . 001 ) concentrations had the strongest correlation to percent of total body fat located in the trunk among men . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
The entry of cholesterol contained within high density lipoprotein ( HDL ) into adrenocortical cells is mediated by a human homologue of SR BI , CD 36 , and LIMPII Analogous 1 ( CLA 1 ) and thus augmenting their growth . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
The Step 2 diet response showed significant positive correlations between changes in both LDL cholesterol and the ratio of total to HDL cholesterol and baseline percentage body fat , body mass index , and insulin . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
RESULTS : Markers of total body fat / fat distribution ( waist circumference , BMI and WHR ) , inflammation ( IL 6 , CRP and TNF alpha R 2 ) , metabolism ( fasting insulin , HDL , LDL and triglycerides ) and BP ( systolic and diastolic ) correlated with FMD . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NAFLD ( defined as IHF content > 5 % wet weight ) was found in 16 individuals ( 30 % ) in association with higher ALT ( P < 0 . 006 ) , Hb A ( 1c ) ( P = 0 . 021 ) , trunk fat content ( P < 0 . 03 ) , and lower HDL cholesterol ( P < 0 . 05 ) . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
RESULTS : The 26 % carbohydrate , low saturated fat diet reduced triacylglycerol , apolipoprotein B , small LDL mass , and total : HDL cholesterol and increased LDL peak diameter . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
The magnitude of the association with CHD is considerably stronger than for saturated fat , and is stronger than predicted by the effects of TFA on LDL and HDL cholesterol . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
FABP 2 promoter haplotypes or genotype combinations defined by the promoter and Ala54Thr polymorphism were not associated with BMI , body fat , leptin , HbA ( 1c ) , total cholesterol or HDL . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Dietary carbohydrate tends to increase plasma triglyceride when it displaces fat , accompanied by a decrease in HDL cholesterol concentrations . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Insulin sensitivity ( assessed by homeostasis model assessment 2 modeling ) , androgen , and HDL cholesterol levels were significantly decreased , whereas total fat mass and LDL cholesterol , triglyceride , CRP , leptin , and fructosamine levels were significantly increased in untreated Klinefelter ' s syndrome patients . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Differences in measures of glucose and HDL intravascular processing attributable to dietary fat were small . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
High intakes of total and saturated fat were associated with reduced HDL cholesterol concentrations in men with birth weights < or =3 . 2 kg ( 7 lb ) but not in men with higher birth weights . ^^^ Similar effects on the HDL to LDL cholesterol ratio were observed ( P for interaction = 0 . 02 for total fat and 0 . 01 for saturated fat ) . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Regardless of fat content in the diet , the doses of hydroxycut used significantly decreased fasting serum concentrations of cholesterol , triacylglycerol ( TAG ) , low density lipoprotein ( LDL ) cholesterol , total apolipoprotein B ( apo B ) , and LDL / high density lipoprotein ( HDL ) cholesterol ratio . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
RESULTS : The correlation analysis showed that HOMA IR was positively correlated with percent body fat ( r = 0 . 32 , P < 0 . 05 ) , BMI ( r = 0 . 46 , P < 0 . 01 ) , serum triglyceride ( TG ) ( r =0 . 29 , P < 0 . 01 ) , and mean arterial pressure ( r =0 . 25 , P < 0 . 05 ) , but not significantly correlated with GFR , age , cholesterol , HDL , uric acid and 24 hr urinary protein . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
CONCLUSIONS : Consumption of a saturated fat reduces the anti inflammatory potential of HDL and impairs arterial endothelial function . ^^^ In contrast , the anti inflammatory activity of HDL improves after consumption of polyunsaturated fat . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
In the obese group , plasma adiponectin concentrations showed a strong positive association with concentrations of HDL cholesterol ( P < 0 . 0001 ) and negative associations with LDL cholesterol , triglycerides , high sensitivity C reactive protein , interleukin 6 , apolipoprotein B ( 100 ) , soluble E selectin , soluble vascular cellular adhesion molecule 1 , plasminogen activator inhibitor 1 , leukocyte count , and liver and intramyocellular fat ( all P < 0 . 03 ) . ^^^ In the lean group , adiponectin showed a less strong association with HDL cholesterol ( P = 0 . 005 ) and liver fat ( P = 0 . 03 ) and no significant associations with the other variables ( all P > 0 . 10 ) . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
The main outcome measure was the correlations between plasma adiponectin and adiposity variables ( the body mass index , the sum of 4 skinfolds , waist circumference [ WC ] , and percent body fat [ bioimpedance ] ) , blood pressure , plasma glucose , triglycerides , high density lipoprotein ( HDL ) cholesterol and insulin . ^^^ These results suggest that , in apparently healthy children , adiponectin is related to the level of HDL cholesterol independently of fat mass . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
We investigated the correlation between fasting serum insulin level , FPG , leptin or adiponectin , and body mass index ( BMI ) , fat mass ( FM ) , triglycerides ( TGs ) , high density lipoprotein ( HDL ) cholesterol , or preheparin serum lipoprotein lipase ( LPL ) as parameters of insulin resistance . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
Trunk to limb fat ratio decreased significantly in both ( P < 0 . 001 ) compared with PL , as did total cholesterol and non high density lipoprotein ( HDL ) cholesterol ( 4 . 5 % and 7 . 5 % in DD , 4 . 3 % and 6 . 2 % in AD ) . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
The candidate genes were selected based on their functions , including insulin resistance ( APM 1 , CD 36 , HSD11B1 ) , oxidative stress ( CYBA , GPX 1 , GSTMs ) , steroid hormone ( ESR 1 , ESR 2 , HSD11B2 ) , renal functions ( PTGS 2 , KLK 1 , NPHS 1 , NPHS 2 , SGK , SLC12A1 , PTGES ) , and others related to cardiovascular physiology ( GJA 4 , NOS 1 , NTRK 3 , P2RX4 , SPP 1 , ALDH 2 ) . ^^^
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA
Interacting proteins: P28845 and P16671	Pubmed	SVM Score :0.0
NA